Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Michael R. Ma"'
Autor:
Perry S. Choi, MD, Amit Sharir, BS, Yoshikazu Ono, MD, Masafumi Shibata, MD, Alexander D. Kaiser, PhD, Yellappa Palagani, PhD, Alison L. Marsden, PhD, Michael R. Ma, MD
Publikováno v:
JTCVS Open, Vol 22, Iss , Pp 395-404 (2024)
Objective: The study objective was to investigate the effect of free-edge length on valve performance in bicuspidization repair of congenitally diseased aortic valves. Methods: In addition to a constructed unicuspid aortic valve disease model, 3 repr
Externí odkaz:
https://doaj.org/article/c1be7404d01545efadb38b2f194354dd
Autor:
Peter Kip, Thijs J. Sluiter, Michael R. MacArthur, Ming Tao, Nicky Kruit, Sarah J. Mitchell, Jonathan Jung, Sander Kooijman, Josh Gorham, Jonathan G. Seidman, Paul H. A. Quax, Julius L. Decano, Masanori Aikawa, C. Keith Ozaki, James R. Mitchell, Margreet R. de Vries
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Short-term preoperative methionine restriction (MetR) is a promising translatable strategy to mitigate surgical injury response. However, its application to improve post-interventional vascular remodeling remains underexplored. Here we find
Externí odkaz:
https://doaj.org/article/8f299f54c6294dc69d98482c052be4d7
Autor:
Amelia Y. Bryan, E. Brandon Strong, Sumanth Kidambi, Shane Gilligan-Steinberg, Ross Bennett-Kennett, James Y. Lee, Annabel Imbrie-Moore, Stephen C. Moye, Sebastian Hendrickx-Rodriguez, Hanjay Wang, Reinhold H. Dauskardt, Y. Joseph Woo, Michael R. Ma
Publikováno v:
World Journal for Pediatric and Congenital Heart Surgery. 13:166-174
Background Neo-aortic pulmonary autografts often experience root dilation and valve regurgitation over time. This study seeks to understand the biomechanical differences between aortic and neo-aortic pulmonary roots using a heart simulator. Methods P
Autor:
Sumanth Kidambi, Stephen C. Moye, James Lee, Teaghan H. Cowles, E. Brandon Strong, Rob Wilkerson, Michael J. Paulsen, Y. Joseph Woo, Michael R. Ma
Publikováno v:
Seminars in thoracic and cardiovascular surgery.
We sought to understand how leaflet forces change in response to annular dilation and leaflet tethering (LT) in single ventricle physiology. Explanted fetal bovine tricuspid valves were sutured onto image-derived annuli and ventricular mounts. Contro
Autor:
Natalie S. Lui, F. Christopher Holsinger, Michael R. Ma, Jeffrey R. Janus, Karthik Balakrishnan
Publikováno v:
JTCVS techniques. 16
Slide tracheoplasty is the standard technique to repair congenital long-segment tracheal stenosis. This operation most commonly requires median sternotomy, which has drawbacks in young children. We hypothesized that a transcervical approach without s
Autor:
Jas Virk, Jasmin Gill, Fatemeh Fekrmandi, Austin Iovoli, Mark Farrugia, Ayham Al-Afif, Kimberly Wooten, Vishal Gupta, Ryan McSpadden, Moni A. Kuriakose, Michael R. Markiewicz, Wesley L. Hicks, Sung Jun Ma, Anurag K. Singh
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background The National Comprehensive Cancer Network (NCCN) guideline recommends consideration of weekly cisplatin as an alternative option for patients with head and neck cancer undergoing definitive chemoradiation. However, in a recent pha
Externí odkaz:
https://doaj.org/article/de9e2bea3e504f46b2b182d8f4c6b429
Autor:
Ozlem Altintas, Michael R. MacArthur
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
The function of General Control Nonderepressible 2 (GCN2), an evolutionary-conserved component of the integrated stress response (ISR), has been well-documented across organisms from yeast to mammals. Recently GCN2 has also gained attention for its r
Externí odkaz:
https://doaj.org/article/bc0f1257d52f496ab9d6289b074e5a10
Publikováno v:
Frontiers in Chemical Biology, Vol 3 (2024)
Maintaining cellular redox homeostasis is critical for cell viability and growth, with disruptions implicated in cellular responses to chemicals and drugs. This study investigates the interactions between acylfulvenes (AFs), a class of DNA alkylating
Externí odkaz:
https://doaj.org/article/b0fa27b5694e463abfed807a66329e43
Autor:
Thomas Agius, Raffaella Emsley, Arnaud Lyon, Michael R. MacArthur, Kevin Kiesworo, Anna Faivre, Louis Stavart, Martine Lambelet, David Legouis, Sophie de Seigneux, Déla Golshayan, Francois Lazeyras, Heidi Yeh, James F. Markmann, Korkut Uygun, Alejandro Ocampo, Sarah J. Mitchell, Florent Allagnat, Sébastien Déglise, Alban Longchamp
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Dietary restriction promotes resistance to surgical stress in multiple organisms. Counterintuitively, current medical protocols recommend short-term carbohydrate-rich drinks (carbohydrate loading) prior to surgery, part of a multimodal perio
Externí odkaz:
https://doaj.org/article/ffeaabec74c8436cb692b16a68581716
Autor:
Gabriele A. Fontana, Michael R. MacArthur, Nadezhda Rotankova, Michela Di Filippo, Hans-Dietmar Beer, Hailey L. Gahlon
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Cancer-associated fibroblasts (CAFs) are components of the tumor microenvironment and represent appealing therapeutic targets for translational studies. Conventional protein-based biomarkers for CAFs have been reported to be limited in their
Externí odkaz:
https://doaj.org/article/ca62f4fffb3c48d1959e69907344cee2