Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Michael R. Lassen"'
Autor:
Fisseha Tesfaye, Michael R. Lassen, John Strony, Renée M Swaim, Jeffrey I. Weitz, Gary Peters, Gary E. Raskob, Lee Michael, Peter M DiBattiste, Charles W. Francis, Annelise Segers, Takeshi Fuji, Robin S. Roberts
Publikováno v:
Journal of Thrombosis and Haemostasis
BACKGROUND JNJ-9375 is an antibody against exosite 1 on thrombin, inhibits substrate binding but not catalytic activity. OBJECTIVE To examine the possibility that JNJ-9375 attenuates thrombosis without affecting hemostasis, we compared the efficacy a
Autor:
Jeffrey I. Weitz, Kenneth W. Mahaffey, Annelise Segers, Walter Ageno, Robin Roberts, John Strony, Elaine M. Hylek, Michael R. Lassen, David Gailani, Ravi S Notani, Gary E. Raskob, Axiomatic-Tkr Investigators
Publikováno v:
N Engl J Med
BACKGROUND: Factor XIa inhibitors for the prevention and treatment of venous and arterial thromboembolism may be more effective and result in less bleeding than conventional anticoagulants. Additional data are needed regarding the efficacy and safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94db605dba8c04157988c9a6f61c61ee
https://europepmc.org/articles/PMC9540352/
https://europepmc.org/articles/PMC9540352/
Autor:
Michael R. Lassen, Scott D. Berkowitz, Bastian Becker, Jeffrey I. Weitz, Rupert Bauersachs, Gary E. Raskob, Maria C. S. Freitas, Carola Metzig
Publikováno v:
JAMA
Importance The efficacy of factor XIa inhibition for thromboprophylaxis is unknown. Osocimab is a long-acting, fully human monoclonal antibody that inhibits factor XIa. Objective To compare different doses of osocimab with enoxaparin and apixaban for
Autor:
Steffen Thiel, Anette Tarp Hansen, Christine Lodberg Hvas, Anne-Mette Hvas, Michael R. Lassen, Anita Sylvest Andersen, Julie Brogaard Larsen
Publikováno v:
Larsen, J B, Andersen, A S, Hvas, C L, Thiel, S, Lassen, M R, Hvas, A-M & Hansen, A T 2019, ' Lectin pathway proteins of the complement system in normotensive pregnancy and preeclampsia ', American Journal of Reproductive Immunology
, vol. 81, no. 4, e13092, pp. 1-11 . https://doi.org/10.1111/aji.13092
Larsen, J B, Andersen, A S, Hvas, C L, Thiel, S, Lassen, M R, Hvas, A-M & Hansen, A T 2019, ' Lectin pathway proteins of the complement system in normotensive pregnancy and pre-eclampsia ', American Journal of Reproductive Immunology Online, vol. 81, no. 4, e13092, pp. e13092 . https://doi.org/10.1111/aji.13092
, vol. 81, no. 4, e13092, pp. 1-11 . https://doi.org/10.1111/aji.13092
Larsen, J B, Andersen, A S, Hvas, C L, Thiel, S, Lassen, M R, Hvas, A-M & Hansen, A T 2019, ' Lectin pathway proteins of the complement system in normotensive pregnancy and pre-eclampsia ', American Journal of Reproductive Immunology Online, vol. 81, no. 4, e13092, pp. e13092 . https://doi.org/10.1111/aji.13092
PROBLEM: The lectin pathway of the complement system may be involved in the pathogenesis of preeclampsia. We aimed to investigate changes in serum concentrations of a broad range of lectin pathway proteins during normal pregnancy and their associatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603e2cab57775bc8f4e6e291ba619b8f
https://vbn.aau.dk/ws/files/294525388/Larsen_et_al_2019_American_Journal_of_Reproductive_Immunology.pdf
https://vbn.aau.dk/ws/files/294525388/Larsen_et_al_2019_American_Journal_of_Reproductive_Immunology.pdf
Autor:
Alexander G.G. Turpie, Lorenzo G. Mantovani, Verena Haupt, Michael R. Lassen, Sylvia Haas, Reinhold Kreutz, Kai Vogtländer, Gerlind Holberg
Publikováno v:
Vascular Health and Risk Management, Vol 2016, Iss Issue 1, Pp 209-218 (2016)
Vascular Health and Risk Management
Vascular Health and Risk Management
Sylvia Haas,1 Gerlind Holberg,2 Reinhold Kreutz,3 Michael Rud Lassen,4 Lorenzo Mantovani,5 Verena Haupt,6 Kai Vogtländer,7 Alexander GG Turpie8 1Formerly Technical University of Munich, 2Bayer HealthCare AG, 3Institut für Klinische Pharmakologie un
Autor:
Tor Erik Gudmundsen, Ola E. Dahl, Ingebjørg Seljeflot, Trine Lauritzen, Michael R. Lassen, Lars C. Borris, Anniken Haslund, Fredrik Wexels, Are Hugo Pripp
Publikováno v:
Thrombosis Research. 134:68-71
Introduction We have recently reported that increased levels of urine prothrombin fragment 1 + 2 reflected radiologically verified deep vein thrombosis. In this study we evaluated whether urine prothrombin fragment 1 + 2 was associated with pulmonary
Autor:
Takeshi Fuji, Charles Francis, Robin S. Roberts, Jeffrey I. Weitz, Michael R. Lassen, Maureen Johnson, Gary Peters, Gary E. Raskob, Juliane Bernholz, Annelise Segers, John Strony, Michael Lee, Renee Swaim
Publikováno v:
Journal of the American College of Cardiology. 73:2047
JNJ9375 is a monoclonal antibody against exosite-1 on thrombin. JNJ9375 inhibits thrombin binding to its substrates but not its catalytic activity. Consequently, JNJ9375 may attenuate thrombosis without affecting hemostasis. To test this hypothesis,
Autor:
Ingebjørg Seljeflot, Ferencz Laszlo, Anniken Haslund, Tor Erik Gudmundsen, Ola E. Dahl, Lars C. Borris, Are Hugo Pripp, Michael R. Lassen, Fredrik Wexels
Publikováno v:
Thrombosis Research. 131:560-563
The appearance of prothrombin fragment 1 + 2 (F1 + 2) in urine has been associated with postoperative hypercoagulability and thromboembolism. We wanted to assess if F1 + 2 was released in urine (uF1 + 2) in patients with procoagulant disorders, and i
Autor:
Dalei Chen, Gary E. Raskob, Luz Margarita Ramirez, Alexander Gallus, Lu Wang, Graham F. Pineo, Michael R. Lassen, Eduardo Ramacciotti
Publikováno v:
Journal of Thrombosis and Haemostasis. 11:444-451
Summary. Background: New oral anticoagulants for thromboprophylaxis after hip or knee arthroplasty have been given as fixed-dose regimens. Objective: To evaluate the consistency of the antithrombotic efficacy and bleeding risk of apixaban 2.5 mg twic
Autor:
Sylvia Haas, Alexander G.G. Turpie, Michael R. Lassen, Reinhold Kreutz, Lorenzo G. Mantovani, André C Schmidt, Waheed Jamal
Publikováno v:
Vascular Health and Risk Management, Vol 2012, Iss default, Pp 363-370 (2012)
Vascular Health and Risk Management
Vascular Health and Risk Management
Alexander GG Turpie,1 André C Schmidt,2 Reinhold Kreutz,3 Michael R Lassen,4 Waheed Jama,1,2 Lorenzo Mantovani,5 Sylvia Haas61Department of Medicine, Hamilton Health Sciences, General Division, Ontario, Canada; 2Bayer Healthcare Pharmaceuticals, Glo