Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Michael R. Landauer"'
Autor:
Michal Barshishat-Kupper, Elizabeth A. McCart, James G. Freedy, Ashlee J. Tipton, Vitaly Nagy, Sung-Yop Kim, Michael R. Landauer, Gregory P. Mueller, Regina M. Day
Publikováno v:
Proteomes, Vol 3, Iss 3, Pp 249-265 (2015)
Damage to normal lung tissue is a limiting factor when ionizing radiation is used in clinical applications. In addition, radiation pneumonitis and fibrosis are a major cause of mortality following accidental radiation exposure in humans. Although cli
Externí odkaz:
https://doaj.org/article/ddead878dff945efb568cb7b017775ac
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122258 (2015)
We reported that microRNA-30c (miR-30c) plays a key role in radiation-induced human cell damage through an apoptotic pathway. Herein we further evaluated radiation-induced miR-30 expression and mechanisms of delta-tocotrienol (DT3), a radiation count
Externí odkaz:
https://doaj.org/article/7993b844ba9043078716cd0015b4878d
Publikováno v:
Journal of Radiation Research. 60:308-317
There are no FDA-approved drugs that can be administered prior to ionizing radiation exposure to prevent hematopoietic–acute radiation syndrome (H-ARS). A suspension of synthetic genistein nanoparticles was previously shown to be an effective radio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eaca055a330a23f8ba64ad8e74c8f7f
https://doi.org/10.1093/jrr/rrz014
https://doi.org/10.1093/jrr/rrz014
Autor:
Margaret F. Keil, Joanna Westerfield, Michael R. Landauer, Ashley L. Russell, Lawren Wooten, T. John Wu, Robert J. Handa, Darwin O. Larco, Danette F. Cruthirds, Jamie Grimes, Michael J. Weiser
Publikováno v:
Hormone and Metabolic Research. 49:457-465
17β-Estradiol is known to regulate energy metabolism and body weight. Ovariectomy results in body weight gain while estradiol administration results in a reversal of weight gain. Isoflavones, found in rodent chow, can mimic estrogenic effects making
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5f5f763f79f738c2b5435effcaae75
https://doi.org/10.1055/s-0043-108250
https://doi.org/10.1055/s-0043-108250
Autor:
Sung-Yop Kim, Kelley M Dickson, Eric D. Lombardini, Ronald Allan M Panganiban, Rajesh L. Thangapazham, Rihab A Mansur, Michael R. Landauer, Vitaly Nagy, Elizabeth A McCart, Reed Selwyn, Steven R. Mog, Regina M. Day, Thomas N. Darling
Publikováno v:
Journal of Radiation Research
Accidental high-dose radiation exposures can lead to multi-organ injuries, including radiation dermatitis. The types of cellular damage leading to radiation dermatitis are not completely understood. To identify the cellular mechanisms that underlie r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8f842fd4bcdfbfe3399a3c79a3e924
https://doi.org/10.1093/jrr/rrx008
https://doi.org/10.1093/jrr/rrx008
Autor:
Michael J. Weiser, Ashley L. Russell, Lawren Wooten, Danette F. Cruthirds, Jamie Grimes, T. John Wu, Michael R. Landauer, Darwin O. Larco, Joanna Westerfield, Robert J. Handa, Margaret F. Keil
Publikováno v:
Neuroscience letters. 640
Phytoestrogens are plant derived, non-steroidal compounds naturally found in rodent chows that potentially have endocrine-disrupting effects. Isoflavones, the most common phytoestrogens, have a similar structure and molecular weight to 17β-estradiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c5004bf715da13595e0f9cc7e317d5
https://pubmed.ncbi.nlm.nih.gov/28077306
https://pubmed.ncbi.nlm.nih.gov/28077306
Autor:
Dadin Fu, Mang Xiao, Thomas B. Elliott, Vilmar Villa, Cam T. Ha, Mark H. Whitnall, Michael R. Landauer, Sanchita P. Ghosh, Xiang Hong Li, David L. Bolduc
Publikováno v:
Radiation Research. 180:649-657
We recently demonstrated that natural delta-tocotrienol (DT3) significantly enhanced survival in total-body irradiated (TBI) mice, and protected mouse bone marrow cells from radiation-induced damage through Erk activation-associated mTOR survival pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16ac8baf5bcd12e363115b81dfed606
https://doi.org/10.1667/rr13398.1
https://doi.org/10.1667/rr13398.1
Autor:
Ronald Allan M Panganiban, Michal Barshishat-Kupper, Regina M. Day, Thomas A. Davis, Ashlee J. Tipton, Elizabeth A McCart, Ognoon Mungunsukh, Michael R. Landauer
Publikováno v:
Experimental Hematology. 39:293-304
Objective. Our laboratory reported that the angiotensin converting enzyme inhibitor captopril improves erythroid recovery from total body irradiation (TBI) in mice when administered after irradiation. However, captopril administered before TBI attenu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26402d7da27b7603533839a192e5a3c
https://doi.org/10.1016/j.exphem.2010.12.002
https://doi.org/10.1016/j.exphem.2010.12.002
Autor:
Thomas A. Davis, Steven R. Mog, Michael R. Landauer, Mihret F. Amare, Regina M. Day, Michal Barshishat-Kupper, Stephen R. Zins
Publikováno v:
Experimental Hematology. 38:270-281
Objective Angiotensin II (Ang II), a potent vasoconstrictor, affects the growth and development of hematopoietic cells. Mixed findings have been reported for the effects of angiotensin-converting enzyme (ACE) inhibitors on radiation-induced injury to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2881a2a197e736f5a2906b00f3d7f87b
https://doi.org/10.1016/j.exphem.2010.01.004
https://doi.org/10.1016/j.exphem.2010.01.004
Publikováno v:
International Immunopharmacology. 9:1401-1410
The development of an effective pharmacological countermeasure is needed to reduce the morbidity and mortality in military and civilian populations associated with possible exposure to ionizing radiation. We previously demonstrated that a single subc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2f096033a5024bb27bb701db204393
https://doi.org/10.1016/j.intimp.2009.08.012
https://doi.org/10.1016/j.intimp.2009.08.012