Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Michael R. Lamprecht"'
Publikováno v:
BioTechniques, Vol 42, Iss 1, Pp 71-75 (2007)
Careful visual examination of biological samples is quite powerful, but many visual analysis tasks done in the laboratory are repetitive, tedious, and subjective. Here we describe the use of the open-source software, CellProfiler™, to automatically
Externí odkaz:
https://doaj.org/article/590c3f652a8d4422926dcca88b1e1495
Autor:
Michael R. Lamprecht, Barclay Morrison
Publikováno v:
Journal of Neurotrauma. 32:1361-1368
Combination therapies are a promising therapeutic option for traumatic brain injury (TBI) owing to the clinical failure of monotherapy treatments, such as progesterone. Organotypic hippocampal slice cultures (OHSCs) from Sprague-Dawley rats were subj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc08605ae2da282b9a579a5b8258ced8
https://doi.org/10.1089/neu.2015.3912
https://doi.org/10.1089/neu.2015.3912
Publikováno v:
Scientific Reports
Brain is an immensely complex system displaying dynamic and heterogeneous metabolic activities. Visualizing cellular metabolism of nucleic acids, proteins, and lipids in brain with chemical specificity has been a long-standing challenge. Recent devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656b001328ed3b84b191623cd1f00672
https://doi.org/10.1038/srep39660
https://doi.org/10.1038/srep39660
Autor:
Jennifer L Hammers, Benjamin S. Elkin, John F. Crary, Barclay Morrison, Jimmy W. Huh, Michael R. Lamprecht, Kartik Kesavabhotla, Ramesh Raghupathi
Publikováno v:
Journal of neurotrauma. 34(1)
The utility of in vitro models of traumatic brain injury (TBI) depends on their ability to recapitulate the in vivo TBI cascade. In this study, we used a genome-wide approach to compare changes in gene expression at several time points post-injury in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f268398781af361bd3126eb362b2a685
https://pubmed.ncbi.nlm.nih.gov/26919808
https://pubmed.ncbi.nlm.nih.gov/26919808
Publikováno v:
BioTechniques. 42:71-75
Careful visual examination of biological samples is quite powerful, but many visual analysis tasks done in the laboratory are repetitive, tedious, and subjective. Here we describe the use of the open-source software, CellProfiler™, to automatically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3b22634a46b58e1344040db77a4ce2
https://doi.org/10.2144/000112257
https://doi.org/10.2144/000112257
Autor:
Barclay Morrison, Michael R. Lamprecht
Publikováno v:
Brain research. 1563
In this study, we investigated the role of GPR30 in 17β-estradiol- (E2) mediated neuroprotection after an ischemic injury in an organotypic hippocampal slice culture (OHSC) model. We report that after oxygen–glucose deprivation (OGD), a physiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043ad51cd78970b5e3507f7fcdf29067
https://pubmed.ncbi.nlm.nih.gov/24704272
https://pubmed.ncbi.nlm.nih.gov/24704272
Autor:
Rachid Skouta, Caroline E Gleason, Barclay Morrison, Brent R. Stockwell, Wan Seok Yang, Eleina M. Zaitsev, Scott J. Dixon, Michael R. Lamprecht, Andras J. Bauer, Darpan N Patel, Kathryn M. Lemberg, Alexandra M. Cantley
Publikováno v:
Cell. 149(5)
SummaryNonapoptotic forms of cell death may facilitate the selective elimination of some tumor cells or be activated in specific pathological states. The oncogenic RAS-selective lethal small molecule erastin triggers a unique iron-dependent form of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4033817311eb224cb2c47dfa304e3d0
https://pubmed.ncbi.nlm.nih.gov/26350095
https://pubmed.ncbi.nlm.nih.gov/26350095
Publikováno v:
AIP Conference Proceedings.
Among current modalities, ultrasound uniquely offers both millisecond and millimeter accuracy in noninvasively stimulating brain tissue. In addition, by sweeping the ultrasound beam within the refractory period of the neuronal tissue, ultrasonic neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0149a760e8112d86320d8e17e755fbca
https://doi.org/10.1063/1.4757344
https://doi.org/10.1063/1.4757344
Autor:
David M. Sabatini, Anne E. Carpenter, Carson C. Thoreen, David A. Guertin, Siraj M. Ali, Katherine L. Madden, Robert A. Lindquist, Michael R. Lamprecht, Adam Papallo, Peggy P. Hsu, Kathleen A. Ottina, Shomit Sengupta, Thouis R. Jones, Yoav D. Shaul, Douglas B. Wheeler
Publikováno v:
Cold Spring Harbor Laboratory Press
The evolutionarily conserved target of rapamycin complex 1 (TORC1) controls cell growth in response to nutrient availability and growth factors. TORC1 signaling is hyperactive in cancer, and regulators of TORC1 signaling may represent therapeutic tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8a4cf4de0eb3a16d0146240f06adb3
http://hdl.handle.net/1721.1/74542
http://hdl.handle.net/1721.1/74542
Publikováno v:
Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference (NEBEC).
Vertically aligned carbon nanofiber (VACNF) electrode arrays were tested for their potential application in recording neuro-chemical activity. Because the electrodes are carbon-based, these arrays have potential advantages over metal electrodes and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f5f270525844d6f1e9a20a62e9b318a
https://doi.org/10.1109/nebc.2010.5458154
https://doi.org/10.1109/nebc.2010.5458154