Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Michael R. Horsman"'
Autor:
Anne Marit Rykkelid, Priyanshu Manojkumar Sinha, Charlemagne Asonganyi Folefac, Michael R. Horsman, Brita Singers Sørensen, Tine Merete Søland, Olaf Joseph Franciscus Schreurs, Eirik Malinen, Nina Frederike J. Edin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Combining radiation therapy with immunotherapy is a strategy to improve both treatments. The purpose of this study was to compare responses for two syngeneic head and neck cancer (HNC) tumor models in mice following X-ray or proton irradiati
Externí odkaz:
https://doaj.org/article/022de18d025b4177aa9111a2bd052858
Autor:
Anne Marit Rykkelid, Priyanshu Manojkumar Sinha, Charlemagne Asonganyi Folefac, Michael R. Horsman, Brita Singers Sørensen, Tine Merete Søland, Olaf Joseph Franciscus Schreurs, Eirik Malinen, Nina Frederike J. Edin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/93e47516c77c475b8f314a06977f07ac
Publikováno v:
International Journal of Hyperthermia, Vol 38, Iss 1, Pp 105-110 (2021)
Introduction The combination of hyperthermia with low LET (linear energy transfer) radiation may have similar anti-tumor effects as high LET radiation alone. This pre-clinical study determined the optimal heating temperature and time interval between
Externí odkaz:
https://doaj.org/article/71c11d46959542128e0be49e8e9e4513
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-10 (2020)
Abstract Background In vitro experiments using radiolabeled molecules is fundamental for Positron emission tomography (PET) or single photon emission computed tomography (SPECT) tracer development and various metabolic assays, but no consensus on app
Externí odkaz:
https://doaj.org/article/32d93bf9bfdd4094ac476230d327d76a
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Tumor hypoxia is a common feature of the microenvironment in solid tumors, primarily due to an inadequate, and heterogeneous vascular network. It is associated with resistance to radiotherapy and results in a poorer clinical outcome. The presence of
Externí odkaz:
https://doaj.org/article/d031700dff69464da6a30b3c1ad061b8
Publikováno v:
Pharmaceutics, Vol 4, Iss 4, Pp 563-589 (2012)
Antivascular treatments can either be antiangiogenic or targeting established tumour vasculature. These treatments affect the tumour microvasculature and microenvironment but may not change clinical measures like tumour volume and growth. In research
Externí odkaz:
https://doaj.org/article/de8ddbd803cb462ebedb858209f6ca38
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 2, Pp 108-112 (2007)
Combretastatin-A4 disodium phosphate (CA4DP) is a vascular-disruptive agent that causes an abrupt decrease in tumor blood flow. The direct actions of CA4DP include increases in vascular permeability and destabilization of the endothelial cytoskeleton
Externí odkaz:
https://doaj.org/article/1f65a1a91d1e4a2c9dbc4e864b536e6a
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 4, Iss 3, Pp 263-267 (2002)
The potential of noninvasive laser Doppler flowmetry (LDF) and near infrared spectroscopy (NIRS) to detect acute effects of different vascular-modifying agents on perfusion and blood volume in tumors was evaluated. C3H mouse mammary carcinomas (∼20
Externí odkaz:
https://doaj.org/article/26a4fb34b5824b7eb3080073da012cf5
Autor:
Morten Busk, Peter P Eggertsen, Jens Overgaard, Michael R Horsman, Thomas Tørring, Kristian M Jacobsen, Thomas B Poulsen
Hypoxia-activated pro-drugs like TH-302 have failed clinically, possible due to variable activity of drug-activating reductases. Here we compared TH-302 and the natural product BE-43547, that targets hypoxic cells independently of reductases. Tumor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65a49c47bc6cd225d3638ec610a4ca20
https://doi.org/10.21203/rs.3.rs-2755525/v1
https://doi.org/10.21203/rs.3.rs-2755525/v1
Autor:
Pernille Byrialsen Elming, Morten Busk, Thomas Rea Wittenborn, Johan Bussink, Michael R. Horsman, Simon Lønbro
Publikováno v:
Elming, P B, Busk, M, Wittenborn, T R, Bussink, J, Horsman, M R & Lønbro, S 2023, ' The effect of single bout and prolonged aerobic exercise on tumor hypoxia in mice ', Journal of applied physiology (Bethesda, Md. : 1985), vol. 134, no. 3, pp. 692-702 . https://doi.org/10.1152/japplphysiol.00561.2022
Journal of Applied Physiology, 134, 3, pp. 692-702
Journal of Applied Physiology, 134, 692-702
Journal of Applied Physiology, 134, 3, pp. 692-702
Journal of Applied Physiology, 134, 692-702
Item does not contain fulltext The objectives of this study were to investigate 1) the effect of acute aerobic exercise on tumor hypoxia and blood perfusion, 2) the impact of exercise intensity, 3) the duration of the effect, and 4) the effect of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa11ec2695fb4d1ba916fe773511e236
https://pure.au.dk/portal/da/publications/the-effect-of-single-bout-and-prolonged-aerobic-exercise-on-tumor-hypoxia-in-mice(a96bde8e-ce38-40ae-87d5-d963088e473f).html
https://pure.au.dk/portal/da/publications/the-effect-of-single-bout-and-prolonged-aerobic-exercise-on-tumor-hypoxia-in-mice(a96bde8e-ce38-40ae-87d5-d963088e473f).html