Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Michael R. Hoane"'
Autor:
Gail D Anderson, Todd ePeterson, Cole eVonder Haar, Fred M Farin, Theo K Bammler, Eric D Kantor, James W MacDonald, Michael R Hoane
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
The goal of this study was to compare the effects of two inflammatory modulators, erythropoietin (EPO) and anakinra, on functional recovery and brain gene expression following a cortical contusion impact (CCI) injury. Dosage regimens were designed to
Externí odkaz:
https://doaj.org/article/3931ca2075a3481bb1fd78e88d6e487d
Autor:
Michael E. Young, Michael R. Hoane
Publikováno v:
Learn Behav
Young, Clark, Goffus, and Hoane (Learning and Motivation, 40(2), 160–177, 2009) documented significant advantages of linear and nonlinear mixed-effects modeling in the analysis of Morris water maze data. However, they also noted a caution regarding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9853c87cb977e203739999de71f2eb5
https://pubmed.ncbi.nlm.nih.gov/33619694
https://pubmed.ncbi.nlm.nih.gov/33619694
Publikováno v:
Brain Research. 1640:114-129
With the numerous failures of pharmaceuticals to treat traumatic brain injury in humans, more researchers have become interested in combination therapies. This is largely due to the multimodal nature of damage from injury, which causes excitotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58d98f823b0890a5fde0227a53cb678
https://doi.org/10.1016/j.brainres.2015.12.030
https://doi.org/10.1016/j.brainres.2015.12.030
Publikováno v:
Behavioural brain research. 364
Age is a consistent predictor of outcome following traumatic brain injury (TBI). Although children and adolescents have the highest rate of hospitalizations and long-term disabilities, few preclinical studies have attempted to model and treat TBI in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93edff49d572663db921ac5a40f99a9a
https://pubmed.ncbi.nlm.nih.gov/30771366
https://pubmed.ncbi.nlm.nih.gov/30771366
Autor:
Todd C. Peterson, Theo K. Bammler, James W. MacDonald, Eric D. Kantor, Cole Vonder Haar, Gail D. Anderson, Fred M. Farin, Michael R. Hoane
Publikováno v:
The AAPS Journal. 17:1255-1267
In contrast to considerable data demonstrating a decrease in cytochrome P450 (CYP) activity in inflammation and infection, clinically, traumatic brain injury (TBI) results in an increase in CYP and UDP glucuronosyltransferase (UGT) activity. The obje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce47fcadf520ef4c49818c3c2bec1b2
https://doi.org/10.1208/s12248-015-9792-y
https://doi.org/10.1208/s12248-015-9792-y
Autor:
Gail D. Anderson, Eric D. Kantor, James W. MacDonald, Fred M. Farin, Michael R. Hoane, Keith S. McConomy, Todd C. Peterson, Theo K. Bammler
Publikováno v:
Journal of Neurotrauma. 32:765-779
Neuroprotection, recovery of function, and gene expression were evaluated in an animal model of traumatic brain injury (TBI) after a combination treatment of nicotinamide (NAM) and progesterone (Prog). Animals received a cortical contusion injury ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4341b2f32f5ce56acdfd036b6365fe5d
https://doi.org/10.1089/neu.2014.3530
https://doi.org/10.1089/neu.2014.3530
Autor:
Jennica M. Young, Michael R. Hoane
Publikováno v:
Brain research bulletin. 139
After sustaining a traumatic brain injury (TBI), a person’s ability to make daily decisions can be affected. Simple tasks such as, deciding what to wear are no longer effortless choices, but are instead difficult decisions. This study explored the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991a68613c1a73b2826aecbb7d8771ff
https://pubmed.ncbi.nlm.nih.gov/29501800
https://pubmed.ncbi.nlm.nih.gov/29501800
Autor:
Sarah Peruzzaro, Jeffrey S. Smith, Michael R. Hoane, Jonathan Gallagher, Sarah Fluharty, Jacob Dunkerson, David B. Mudd
Publikováno v:
Restorative Neurology and Neuroscience. 31:431-450
Purpose The effectiveness of embryonic stem cell (eSC) therapy has been explored in many models of neurological disease and several research groups have shown that eSC treatment leads to improved outcomes in pre-clinical models of traumatic brain inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f00982f270a41c4aa96dcdbc772b545
https://doi.org/10.3233/rnn-120299
https://doi.org/10.3233/rnn-120299
Publikováno v:
Journal of Neurotrauma. 29:2505-2512
Traumatic brain injury (TBI) results in a multitude of deficits following injury. Some of the most pervasive in humans are the changes that affect frontally-mediated cognitive functioning, such as decision making. The assessment of decision-making be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d399e82557714e3b948ef53d588b67
https://doi.org/10.1089/neu.2012.2388
https://doi.org/10.1089/neu.2012.2388
Publikováno v:
Restorative Neurology and Neuroscience. 30:291-302
Purpose Traumatic brain injury (TBI) is a major health concern today and effective treatments must be developed in order to combat the numerous TBIs that occur each year. Multiple b-vitamins have been shown to have neuroprotective effects, however, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8840e920480bc03e8c903c29c2a924
https://doi.org/10.3233/rnn-2012-110196
https://doi.org/10.3233/rnn-2012-110196