Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Michael R. Flynn"'
Autor:
Eun Young Lee, Richard B. Mailman, Guangwei Du, Michael Goldenberg, Mechelle M. Lewis, Michael R. Flynn, Young Seoub Hong, Lan Kong, Xuemei Huang
Publikováno v:
Parkinsonism Relat Disord
Introduction Manganese (Mn)-induced parkinsonism involves motor symptoms similar to those observed in Parkinson's disease (PD). Previous literature suggests that chronic Mn- exposure may increase PD risk, although Mn-induced clinical syndromes are co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38fb10c1c122fb9cc0a660f0aac1ae0a
https://pubmed.ncbi.nlm.nih.gov/33691274
https://pubmed.ncbi.nlm.nih.gov/33691274
Autor:
Lan Kong, Eun Young Lee, Jeff D. Yanosky, Richard B. Mailman, Mechelle M. Lewis, Michael R. Flynn, Guangwei Du, Xuemei Huang
Publikováno v:
Toxicological Sciences. 168:486-496
Chronic high-level manganese (Mn)-induced neurotoxicity has been associated with Mn accumulation in the basal ganglia and higher risk for developing parkinsonism. Recent studies in Mn-exposed animals revealed Mn accumulation in the hippocampus, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8461a89f41e7dc557af0f1155987d46
https://doi.org/10.1093/toxsci/kfz011
https://doi.org/10.1093/toxsci/kfz011
Publikováno v:
NeuroToxicology. 64:50-59
Although an essential nutrient, manganese (Mn) can be toxic at high doses. There is, however, uncertainty regarding the effects of chronic low-level Mn-exposure. This review provides an overview of Mn-related brain and functional changes based on stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da472af50ab06dbdbb86de8b60635c6
https://doi.org/10.1016/j.neuro.2017.06.011
https://doi.org/10.1016/j.neuro.2017.06.011
Autor:
Richard B. Mailman, Eun Young Lee, Amy H. Herring, Guangwei Du, Rebecca C. Fry, Scott Van Buren, Eric Van Buren, Lan Kong, Xuemei Huang, Michael R. Flynn, Mechelle M. Lewis
Publikováno v:
NeuroToxicology. 57:39-44
Objectives We demonstrated recently that the T1 relaxation rate (R1) captured short-term Mn exposure in welders with chronic, relatively low exposure levels in a cross-sectional study. In the current study, we used a longitudinal design to examine wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6644d3e997b340640e4a3f30c4ecc486
https://doi.org/10.1016/j.neuro.2016.08.012
https://doi.org/10.1016/j.neuro.2016.08.012
Autor:
James R. Connor, Guangwei Du, Mechelle M. Lewis, Lan Kong, Amanda M. Snyder, Richard B. Mailman, Eun Young Lee, Scott Van Buren, Eric Van Buren, Amy H. Herring, Rebecca C. Fry, Qing X. Yang, Xuemei Huang, Michael R. Flynn, Yunqing Li
Publikováno v:
Toxicological Sciences. 150:369-377
Welding has been associated with neurobehavioral disorders. Welding fumes contain several metals including copper (Cu), manganese (Mn), and iron (Fe) that may interact to influence welding-related neurotoxicity. Although welding-related airborne Fe l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d066efd7ceff987a82622fd630c26969
https://doi.org/10.1093/toxsci/kfw003
https://doi.org/10.1093/toxsci/kfw003
Autor:
Lan Kong, Guangwei Du, Eun Young Lee, Daymond Wagner, Paul J. Eslinger, Xuemei Huang, Michael R. Flynn, Richard B. Mailman, Mechelle M. Lewis
Objectives Welding fumes contain several metals including manganese (Mn) and iron (Fe) that may affect the nervous system. Previous studies of potential welding-related neurotoxicity have focused primarily on Mn exposure. The current study examined n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a5fb9b6e1c3e1b440fe8078e7bcf3c
Autor:
Michael R. Flynn, Scott Van Buren, Eric Van Buren, Amy H. Herring, Mechelle M. Lewis, Guangwei Du, Eun Young Lee, Richard B. Mailman, Lan Kong, Xuemei Huang
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 153(1)
Introduction Welding fumes contain several metals including manganese (Mn), iron (Fe), and copper (Cu) that at high exposure may co-influence welding-related neurotoxicity. The relationship between brain accumulation of these metals and neuropatholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e65533e919a903fe1087229d64b06aa
https://pubmed.ncbi.nlm.nih.gov/27466214
https://pubmed.ncbi.nlm.nih.gov/27466214
Autor:
Michael R. Flynn
Publikováno v:
Communications in Statistics - Theory and Methods. 39:3635-3644
This article presents a constrained maximization of the Shapiro Wilk W statistic for estimating parameters of the Johnson S B distribution. The gradient of the W statistic with respect to the minimum and range parameters is used within a quasi-Newton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::999aa5819edc47c8d97205a41bedf84d
https://doi.org/10.1080/03610920903308463
https://doi.org/10.1080/03610920903308463
Publikováno v:
Journal of Occupational and Environmental Hygiene. 7:607-615
Studies of exposure to the lung carcinogen hexavalent chromium (CrVI) from welding tasks are limited, especially within the construction industry where overexposure may be common. In addition, despite the OSHA requirement that the use of engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a43663e2f829b96fa8e7558cde2a5c5
https://doi.org/10.1080/15459624.2010.510105
https://doi.org/10.1080/15459624.2010.510105
Autor:
Michael R. Flynn, Pam Susi
Publikováno v:
Stochastic Environmental Research and Risk Assessment. 24:377-388
Workers are often exposed to mixtures of airborne contaminants which may complicate health studies, risk assessments, and epidemiological investigations. In situations where these mixed exposures are correlated, multivariate probability distributions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7454b0a1a7b35d99c11d51f11e50d63
https://doi.org/10.1007/s00477-009-0327-x
https://doi.org/10.1007/s00477-009-0327-x