Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michael R. Dufault"'
Autor:
Ross C. Gruber, Gregory S. Wirak, Anna S. Blazier, Lan Lee, Michael R. Dufault, Nellwyn Hagan, Nathalie Chretien, Michael LaMorte, Timothy R. Hammond, Agnes Cheong, Sean K. Ryan, Andrew Macklin, Mindy Zhang, Nilesh Pande, Evis Havari, Timothy J. Turner, Anthony Chomyk, Emilie Christie, Bruce D. Trapp, Dimitry Ofengeim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Neuroinflammation in the central nervous system (CNS), driven largely by resident phagocytes, has been proposed as a significant contributor to disability accumulation in multiple sclerosis (MS) but has not been addressed therapeutically. Br
Externí odkaz:
https://doaj.org/article/7240258f9fe44a898fcf295ec6f91164
Publikováno v:
Molecular Genetics and Metabolism. 138:107526
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c139b8bb3ef77159853fa0416dc1a666
https://doi.org/10.1016/j.ymgme.2023.107526
https://doi.org/10.1016/j.ymgme.2023.107526
Autor:
Kelly Keefe, Tanya Koellner, Michael R. Dufault, S. Pablo Sardi, Mindy Zhang, Robin J. Ziegler, Allyson Anding, Alexander Brezzani, Bridge Hunter, Kaitlyn Baranowski, Kelly George
Publikováno v:
Molecular Genetics and Metabolism. 132:S15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64e11c20d31c2d1d20480efa9ecfdb42
https://doi.org/10.1016/j.ymgme.2020.12.012
https://doi.org/10.1016/j.ymgme.2020.12.012
Autor:
Joseph Gans, Rajashree McLaren, Yide Jiang, Kara Carter, Beverly A. Teicher, Stephen L. Madden, Michael Booker, Yinyin Huang, Tatiana Gladysheva, Beirong Liang, Mark A. Goldberg, Paul T. Mason, Mindy Zhang, Hans-Peter Biemann, James Lillie, Lilly Chai, Katherine W. Klinger, Ann Byrne, Michael R. Dufault
Publikováno v:
Experimental Cell Research. 316:258-271
The PSMD14 (POH1, also known as Rpn11/MPR1/S13/CepP1) protein within the 19S complex (19S cap; PA700) is responsible for substrate deubiquitination during proteasomal degradation. The role of PSMD14 in cell proliferation and senescence was explored u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571576d936cfa44aaacbf7a53d027a86
https://doi.org/10.1016/j.yexcr.2009.08.018
https://doi.org/10.1016/j.yexcr.2009.08.018
Autor:
Cecile Rouleau, Michelle Callahan, Brenden Lucey, Xiaoming Zhang, Stephen L. Madden, Brian P. Cook, Beverly A. Teicher, Michael R. Dufault, Viatcheslav R. Akmaev, John Laterra, Thia St. Martin, Jennifer Walter-Yohrling, Wen Zhang, Kevin A. Walter, Clarence J. Wang, Yide Jiang, Mariana Nacht, Bruce L. Roberts, Katherine W. Klinger, William Weber, Eleanor B. Carson-Walter, Xiaohong Cao, Radu V. Stan
Publikováno v:
The American Journal of Pathology. 165:601-608
Malignant gliomas are uniformly lethal tumors whose morbidity is mediated in large part by the angiogenic response of the brain to the invading tumor. This profound angiogenic response leads to aggressive tumor invasion and destruction of surrounding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f653721d21ccfc02e6e805d4dda5cb73
https://doi.org/10.1016/s0002-9440(10)63324-x
https://doi.org/10.1016/s0002-9440(10)63324-x
Autor:
Siegfried Scherneck, Katrin Bandick, Alfons Meindl, Michael R. Dufault, Kerstin Rhiem, Christine Hüttner, Celia von Lindern, Caroline Nestle-Krämling, Rita K. Schmutzler, Astrid Golla, Beate Betz, W. Hofmann, Barbara Wappenschmidt, Peter Dall, Marion Kiechle, Walter Jonat, Michael Untch, Dieter Niederacher, Norbert Arnold, Andrea Pietschmann
Publikováno v:
International Journal of Cancer. 110:320-325
To establish the importance of CHEK2 mutations for familial breast cancer incidence in the German population, we have screened all 14 of the coding exons in 516 families negative for mutations in both the BRCA1 and BRCA2 genes. We found 12 distinct v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f84983ef5439bc44a0a5e7e060317946
https://doi.org/10.1002/ijc.20073
https://doi.org/10.1002/ijc.20073
Autor:
J. George Gibbings, Sawsan Khuri, Brian P. Cook, Stephen L. Madden, Jim M. Dunwell, Michael R. Dufault, Chris J. Turnbull
Publikováno v:
Plant Biotechnology Journal. 1:271-285
We have compiled two comprehensive gene expression profiles from mature leaf and immature seed tissue of rice (Oryza sativa ssp. japonica cultivar Nipponbare) using Serial Analysis of Gene Expression (SAGE) technology. Analysis revealed a total of 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b35d4db6a8470c62ee2b29680093353
https://doi.org/10.1046/j.1467-7652.2003.00026.x
https://doi.org/10.1046/j.1467-7652.2003.00026.x
Autor:
Joshua Pacheco, Wei-Lien Chuang, James Lillie, Stephen L. Madden, Diane Copeland, Kara Carter, Beverly A. Teicher, Seng H. Cheng, Yide A. Jiang, Mark A. Goldberg, Ann Byrne, Yibin Xiang, Rajashree McLaren, Lilly Chai, Mindy Zhang, Michael R. Dufault, John P. Leonard, Michael J. Vasconcelles, Yinyin Huang, Xiaokui Zhang, Katherine W. Klinger, Shruti Madhiwalla
Publikováno v:
International journal of oncology. 38(3)
Glucosylceramide synthase (GCS) is a key enzyme engaged in the biosynthesis of glycosphingolipids and in regulating ceramide metabolism. Studies exploring alterations in GCS activity suggest that the glycolase may have a role in chemosensitizing tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8db1b71a1f62003c5cc04fe6e11e9d9
https://pubmed.ncbi.nlm.nih.gov/21186402
https://pubmed.ncbi.nlm.nih.gov/21186402
Autor:
J George, Gibbings, Brian P, Cook, Michael R, Dufault, Stephen L, Madden, Sawsan, Khuri, Chris J, Turnbull, Jim M, Dunwell
Publikováno v:
Plant biotechnology journal. 1(4)
We have compiled two comprehensive gene expression profiles from mature leaf and immature seed tissue of rice (Oryza sativa ssp. japonica cultivar Nipponbare) using Serial Analysis of Gene Expression (SAGE) technology. Analysis revealed a total of 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::589d36670cc0ac9dd423a1ae894bcea6
https://pubmed.ncbi.nlm.nih.gov/17163904
https://pubmed.ncbi.nlm.nih.gov/17163904
Autor:
Stephen L. Madden, Michael R. Dufault, Sharon D. Morgenbesser, Viatcheslav R. Akmaev, Rajashree McLaren, Paula J. Kaplan-Lefko, Brenda Richards, Katherine W. Klinger, Clarence J. Wang, Brian P. Cook, Xiahong Cao, Mindy Zhang, Beverly A. Teicher, Scott F. Winter, Norman M. Greenberg, Nora D. Mineva, Barbara A. Foster
Publikováno v:
The Prostate. 67(1)
BACKGROUND A major focus of prostate cancer research has been to identify genes that are deregulated during tumor progression, potentially providing diagnostic markers and therapeutic targets. METHODS We have employed serial analysis of gene expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912f2a133cb46bbaade89c0c88425fa1
https://pubmed.ncbi.nlm.nih.gov/17013881
https://pubmed.ncbi.nlm.nih.gov/17013881