Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Michael R. Drew"'
Autor:
Michael R. Williamson, Stephanie P. Le, Ronald L. Franzen, Nicole A. Donlan, Jill L. Rosow, Mathilda S. Nicot-Cartsonis, Alexis Cervantes, Benjamin Deneen, Andrew K. Dunn, Theresa A. Jones, Michael R. Drew
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Stroke enhances proliferation of neural precursor cells within the subventricular zone (SVZ) and induces ectopic migration of newborn cells towards the site of injury. Here, we characterize the identity of cells arising from the SVZ after st
Externí odkaz:
https://doaj.org/article/e35e75126ba74ef187efe215487b2323
Autor:
Iku Tsutsui-Kimura, Hiroyuki Takiue, Keitaro Yoshida, Ming Xu, Ryutaro Yano, Hiroyuki Ohta, Hiroshi Nishida, Youcef Bouchekioua, Hideyuki Okano, Motokazu Uchigashima, Masahiko Watanabe, Norio Takata, Michael R. Drew, Hiromi Sano, Masaru Mimura, Kenji F. Tanaka
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
D2 receptor-expressing medium spiny neurons (D2-MSNs) are thought to suppress goal-directed behaviours. Here authors ablate D2-MSNs specifically in the ventrolateral striatum, and find that surprisingly, it leads to a reduction in goal-directed motiv
Externí odkaz:
https://doaj.org/article/db122104311e48c9b21cce00826f3e10
Autor:
Sarah A. Wolfe, Emily R. Workman, Chelcie F. Heaney, Farr Niere, Sanjeev Namjoshi, Luisa P. Cacheaux, Sean P. Farris, Michael R. Drew, Boris V. Zemelman, R. Adron Harris, Kimberly F. Raab-Graham
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Alcohol is thought to lead to neuroadaptive changes, although the underlying molecular mechanisms are unclear. Here, the authors find ethanol treatment alters GABAB-receptor expression via fragile-X mental retardation protein in mice, leading to anti
Externí odkaz:
https://doaj.org/article/e5cec5c74cef40f9abc05988792bd8e3
Publikováno v:
Comparative Cognition & Behavior Reviews, Vol 5, Pp 1-22 (2010)
Externí odkaz:
https://doaj.org/article/ce89aa4964734034bd3547474a2d0153
Autor:
Kylie A. Huckleberry, Gary A. Kane, Rita eMathis, Sarah eCook, Jon E. Clutton, Michael R. Drew
Publikováno v:
Frontiers in Systems Neuroscience, Vol 9 (2015)
Thousands of neurons are born each day in the dentate gyrus (DG), but many of these cells die before reaching maturity. Both death and survival of adult-born neurons are regulated by neuronal activity in DG. The immediate-early gene (IEG) zif268 is a
Externí odkaz:
https://doaj.org/article/66165eaa222544828be8b140d56a4396
Autor:
Michael R. Williamson, Stephanie P. Le, Ronald L. Franzen, Nicole A. Donlan, Jill L. Rosow, Andrew K. Dunn, Theresa A. Jones, Michael R. Drew
Stroke enhances proliferation of neural precursor cells within the subventricular zone (SVZ) and induces ectopic migration of newborn cells towards the site of injury. Here we characterize the identity of cells arising from the SVZ after stroke and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4bcf32946bd939650592682dbfed7cf
https://doi.org/10.1101/2022.06.14.496078
https://doi.org/10.1101/2022.06.14.496078
Publikováno v:
Neuropsychopharmacology
Chronic stress is a risk factor for a variety of psychiatric disorders, including depression. Although impairments to motivated behavior are a major symptom of clinical depression, little is known about the circuit mechanisms through which stress imp
Autor:
Michael R. Drew, Cathleen Joy A. Fuertes, Michael R. Williamson, Ronald L. Franzen, Andrew K. Dunn, Theresa A. Jones
Publikováno v:
J Neurosci
Stroke causes remodeling of vasculature surrounding the infarct, but whether and how vascular remodeling contributes to recovery are unclear. We established an approach to monitor and compare changes in vascular structure and blood flow with high spa
Publikováno v:
Nature Neuroscience. 22:770-777
The ability to sustain goal-directed action is essential for success in many domains, but little is known about the corresponding neural substrates. Using fiber photometry to monitor population neural activity, we demonstrate that engagement in susta
Publikováno v:
Stroke. 52
Astrocytes and blood vessels interact closely in the neurovascular unit. After stroke, reactive astrocytes surrounding the infarct undergo structural and functional changes. Simultaneously, considerable plasticity of vascular structure occurs, includ