Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael R. Dent"'
Lipid membranes are crucial for cellular integrity and regulation, and tight control of their structural and mechanical properties is vital to ensure that they function properly. Fluorescent probes sensitive to the mem-brane’s microenvironment are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50105bc7f90de56488bc672e5873ae8c
https://doi.org/10.26434/chemrxiv-2023-nz4bt-v2
https://doi.org/10.26434/chemrxiv-2023-nz4bt-v2
Lipid membranes are crucial for cellular metabolism, and their correct function has been linked to a tight regulation of their structural and mechanical properties, such as viscosity. Fluorescent probes sensitive to the membrane’s environ- are bein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5704d7105a52718eae5f392947fb01d9
https://doi.org/10.26434/chemrxiv-2023-nz4bt
https://doi.org/10.26434/chemrxiv-2023-nz4bt
Autor:
Alexander J. Thompson, Marina K. Kuimova, Jan Michiels, Michael R. Dent, Johan Hofkens, Nicholas J. Brooks, Jacek T. Mika
Publikováno v:
Biophysical Journal. 111(7):1528-1540
The viscosity is a highly important parameter within the cell membrane, affecting the diffusion of small molecules and, hence, controlling the rates of intracellular reactions. There is significant interest in the direct, quantitative assessment of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c6cd639afd6959b6162e74d5f400eb
Autor:
Douglas Wylie, Ian R. Gould, Callum J. Dickson, Phoom Chairatana, Harry L. Anderson, Marina K. Kuimova, Michael R. Dent, Ismael López-Duarte, Aurimas Vyšniauskas, Nicholas J. Brooks
Publikováno v:
Chemical Communications. 52:13269-13272
Molecular rotors have emerged as versatile probes of microscopic viscosity in lipid bilayers, although it has proved difficult to find probes that stain both phases equally in phase-separated bilayers. Here, we investigate the use of a membrane-targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe77e8853a57f33c340c95100f9f4be9
https://doi.org/10.1039/c6cc05954f
https://doi.org/10.1039/c6cc05954f
Autor:
Callum J. Dickson, Michael R. Dent, Marina K. Kuimova, Ismael López-Duarte, Jonathan M. Cooper, Ian R. Gould, Rob Krams, James A. Bull, Nicholas J. Brooks, Niall D. Geoghegan
Publikováno v:
Physical Chemistry Chemical Physics. 17:18393-18402
In order to fully understand the dynamics of processes within biological lipid membranes, it is necessary to possess an intimate knowledge of the physical state and ordering of lipids within the membrane. Here we report the use of three molecular rot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84e8eb04be995ad8e331a7bc9f69ce4
https://doi.org/10.1039/c5cp01937k
https://doi.org/10.1039/c5cp01937k
Autor:
Andrew Glidle, Michael R. Dent, David J. Paterson, Niall D. Geoghegan, Nicholas J. Brooks, Marina K. Kuimova, Jonathan M. Cooper
Publikováno v:
Optics in the Life Sciences.
A new method for imaging membrane viscosity is presented using molecular rotors and a combined TIRF-FLIM approach. Lifetimes of artificial membranes of pure DOPC and DPPC were measured and DOPC over a range of temperatures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd2796bf9633bc0e8759eeaeee4aa960
https://doi.org/10.1364/boda.2015.ot4d.3
https://doi.org/10.1364/boda.2015.ot4d.3
Autor:
Gareth J. Price, Michael R. Dent
Publikováno v:
Journal of Chromatography A. 585:83-92
The UNIFAC group contribution method and its free volume modified version have been used to calculate thermodynamic activity coefficients and hence specific retention volumes for a number of solutes at infinite dilution in a range of polymeric gas-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::806c8a9dfa94e2c606a9006bac6aaef3
https://doi.org/10.1016/0021-9673(91)85060-s
https://doi.org/10.1016/0021-9673(91)85060-s
Autor:
Michael R. Dent, Gareth J. Price
Publikováno v:
Polymer. 31:1745-1749
The UNIFAC group contribution method has been used to calculate the free energy of mixing versus composition curves for several polymer-plasticizer systems, including phthalates and stearates with poly(vinyl chloride). The solubility of the plasticiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b4748befc57316bc9ce52f602ffe546
https://doi.org/10.1016/0032-3861(90)90196-6
https://doi.org/10.1016/0032-3861(90)90196-6
Autor:
Michael R. Dent, Gareth J. Price
Publikováno v:
Journal of Chromatography A. 483:1-19
The UNIFAC group contribution method and its free volume modified version were used to calculate thermodynamic activity coefficients for a number of solutes at infinite dilution in a range of non-polymeric gas—liquid chromatographic stationary phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f3ef1078badb6d52597c5a7b4ddc245
https://doi.org/10.1016/s0021-9673(01)93106-1
https://doi.org/10.1016/s0021-9673(01)93106-1
Autor:
Juan Gallo, Jon Cooper, Nicholas J. Long, David R. Klug, Michael R. Dent, Keith R. Willison, Douglas Wylie, Mark A. A. Neil, Duncan Casey, Nicholas J. Brooks, Steven L. Neale, Ali Salehi-Reyhani, Oscar Ces, Rab Wilson
Publikováno v:
University of Bristol-PURE
Scopus-Elsevier
Scopus-Elsevier
We demonstrate controllable poration within ≈1 µm regions of individual cells, mediated by a near-IR laser interacting with thin-layer amorphous silicon substrates. This technique will allow new experiments in single-cell biology, particularly in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472c72160b81d969490cfe39eb84743b