Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael R. Chong"'
Autor:
Nazia Pathan, Wei Q. Deng, Matteo Di Scipio, Mohammad Khan, Shihong Mao, Robert W. Morton, Ricky Lali, Marie Pigeyre, Michael R. Chong, Guillaume Paré
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract It has been postulated that rare coding variants (RVs; MAF 5%, with height having the highest h 2 RV at 21.9% (95% CI: 19.0-24.8%). The total heritability, including common and rare variants, recovered pedigree-based estimates for 11 traits.
Externí odkaz:
https://doaj.org/article/c178b4267dff4643bed6e59ce258ffbb
Autor:
Yong Li, Yurong Cheng, Francesco Consolato, Guglielmo Schiano, Michael R. Chong, Maik Pietzner, Ngoc Quynh H. Nguyen, Nora Scherer, Mary L. Biggs, Marcus E. Kleber, Stefan Haug, Burulça Göçmen, Marie Pigeyre, Peggy Sekula, Inga Steinbrenner, Pascal Schlosser, Christina B. Joseph, Jennifer A. Brody, Morgan E. Grams, Caroline Hayward, Ulla T. Schultheiss, Bernhard K. Krämer, Florian Kronenberg, Annette Peters, Jochen Seissler, Dominik Steubl, Cornelia Then, Matthias Wuttke, Winfried März, Kai-Uwe Eckardt, Christian Gieger, Eric Boerwinkle, Bruce M. Psaty, Josef Coresh, Peter J. Oefner, Guillaume Pare, Claudia Langenberg, Jürgen E. Scherberich, Bing Yu, Shreeram Akilesh, Olivier Devuyst, Luca Rampoldi, Anna Köttgen
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Uromodulin (UMOD) is a major risk gene for monogenic and complex forms of kidney disease. The encoded kidney-specific protein uromodulin is highly abundant in urine and related to chronic kidney disease, hypertension, and pathogen defense. To gain in
Externí odkaz:
https://doaj.org/article/214e08c2c25c48b684ea1de9af2965d4
Autor:
Sukrit Narula, Pedrum Mohammadi-Shemirani, Stefanie Aeschbacher, Michael R. Chong, Ann Le, Sébastien Thériault, Kirsten Grossman, Guillaume Paré, Lorenz Risch, Martin Risch, David Conen
Genetic predisposition is a risk factor for office hypertension. We tested whether genetic background could identify individuals with ambulatory daytime hypertension in a sample of white Europeans from Liechtenstein. We evaluated two measures of pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::541e21fce7a7ae1d1702879edd349c1e
https://doi.org/10.1101/2022.12.21.22282423
https://doi.org/10.1101/2022.12.21.22282423
Autor:
Nazia Pathan, Wei Q. Deng, Mohammad Khan, Matteo Di Scipio, Shihong Mao, Robert W. Morton, Ricky Lali, Marie Pigeyre, Michael R. Chong, Guillaume Paré
It has been postulated that rare coding variants (RVs; MAF5%, with height having the highest h2RV at 21.9% (95% CI: 19.0-24.8%). The total heritability, including common and rare variants, recovered pedigree-based estimates for 11 traits. RARity can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88ccf06605e0827ea6810d83aa83d68e
https://doi.org/10.21203/rs.3.rs-2159360/v1
https://doi.org/10.21203/rs.3.rs-2159360/v1