Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Michael R. Bleavins"'
Autor:
Carissa A. Jock, Joseph D. Paulauskis, David Baker, Eric Olle, Michael R. Bleavins, Kent J. Johnson, Pamela L. Heard
Publikováno v:
BioTechniques, Vol 37, Iss 1, Pp 30-34 (2004)
Externí odkaz:
https://doaj.org/article/192991aabab74a228c5c29ea9022e552
Autor:
Michael R. Bleavins, Ramin Rahbari
Publikováno v:
Biomarkers in Drug Discovery and Development. :537-551
The emphasis on biomarkers as a new approach often has lead to expectations that the ideal biomarker must be novel and/or exotic. To answer the pertinent questions during drug development, teams often embark on the quest for the “unicorn” of biom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98c7c54ca5a0fb4e030bea4d219bd012
https://doi.org/10.1002/9781119187547.ch28
https://doi.org/10.1002/9781119187547.ch28
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbbb89dcd3465b95701c48516207b514
https://doi.org/10.1096/fasebj.2021.35.s1.02195
https://doi.org/10.1096/fasebj.2021.35.s1.02195
This book continues the legacy of a well-established reference within the pharmaceutical industry – providing perspective, covering recent developments in technologies that have enabled the expanded use of biomarkers, and discussing biomarker chara
Autor:
Michael J. Graziano, Judith W. Henck, David Pegg, James Herman, Michael R. Bleavins, Steven Duddy, Kay A. Criswell, Timothy Anderson, Zbigniew Wojcinski
Publikováno v:
Toxicological Sciences. 128:9-21
Pregabalin, (S)-3-(aminomethyl)-5-methylhexanoic acid, binds with high affinity to the α(2)δ subunit of voltage-gated calcium channels and exerts analgesic, anxiolytic, and antiseizure activities. Two-year carcinogenicity studies were completed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8646c687a61576a0d44d11ce2f033ef1
https://doi.org/10.1093/toxsci/kfs146
https://doi.org/10.1093/toxsci/kfs146
Autor:
Mark S. LaGattuta, Kimberly Gillhouse, Joseph R. Piccotti, Stephanie A. Knight, Michael R. Bleavins
Publikováno v:
Journal of Applied Toxicology. 26:333-340
The local lymph node assay (LLNA) is used to assess the skin sensitization potential of chemicals. In the standard assay, mice are treated topically on the dorsum of both ears with test substance for 3 days. Following 2 days of rest, the initiation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15d93753af019500d6d272718d4d947
https://doi.org/10.1002/jat.1145
https://doi.org/10.1002/jat.1145
Autor:
Joseph D. Paulauskis, Kent J. Johnson, Pamela L. Heard, Michael R. Bleavins, Carissa A. Jock, Eric W. Olle, David Baker
Publikováno v:
BioTechniques. 37:30-34
Timing is Everything Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) is a robust platform for protein profiling and differential gene expression analysi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4ddd131c525e708cb4174cd5ab5c36
https://doi.org/10.2144/04371bm01
https://doi.org/10.2144/04371bm01
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 528:1-18
Our laboratory has previously reported a flow cytometric acridine orange method for detection of micronucleus (MN) in the rat using cyclophosphamide as a test compound. To replace the manual method of scoring and satisfy Good Laboratory Practice (GLP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd50f9e57b83f568544471dcb836538
https://doi.org/10.1016/s0027-5107(03)00077-0
https://doi.org/10.1016/s0027-5107(03)00077-0
Autor:
Michael R. Bleavins
Publikováno v:
The Role of the Study Director in Nonclinical Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ec9ded1ef0b028295a2220e139095d7
https://doi.org/10.1002/9781118873922.ch14
https://doi.org/10.1002/9781118873922.ch14
Publikováno v:
American Journal of Clinical Pathology. 115:376-384
Platelet satellitosis of polymorphonuclear cells is a phenomenon induced or enhanced by the anticoagulant EDTA. In contrast with previously reported studies, the subject in the present case did not demonstrate platelet satellitism but was profoundly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d24eaf21cd333897b4d8f64d360470
https://doi.org/10.1309/mg6t-yqjq-7c74-re1v
https://doi.org/10.1309/mg6t-yqjq-7c74-re1v