Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Michael R. Blatchley"'
Autor:
Michael R. Blatchley, Franklyn Hall, Dimitris Ntekoumes, Hyunwoo Cho, Vidur Kailash, Rafael Vazquez‐Duhalt, Sharon Gerecht
Publikováno v:
Advanced Science, Vol 8, Iss 14, Pp n/a-n/a (2021)
Abstract With the increased realization of the effect of oxygen (O2) deprivation (hypoxia) on cellular processes, recent efforts have focused on the development of engineered systems to control O2 concentrations and establish biomimetic O2 gradients
Externí odkaz:
https://doaj.org/article/a784574896a54252887b1a791753c4c6
Autor:
Michael R. Blatchley, Kristi S. Anseth
Publikováno v:
Nature Reviews Bioengineering. 1:329-345
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cef21cc5bc8e51b743ae6779e0a1fbb7
https://doi.org/10.1038/s44222-023-00039-3
https://doi.org/10.1038/s44222-023-00039-3
Autor:
Taimoor H. Qazi, Michael R. Blatchley, Matthew D. Davidson, F. Max Yavitt, Megan E. Cooke, Kristi S. Anseth, Jason A. Burdick
Publikováno v:
Cell Stem Cell
The recapitulation of complex microenvironments that regulate cell behavior during development, disease, and wound healing is key to understanding fundamental biological processes. In vitro, multicellular morphogenesis, organoid maturation, and disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c4ed0e35e004b1b098e821e4759942
https://doi.org/10.1016/j.stem.2022.03.013
https://doi.org/10.1016/j.stem.2022.03.013
Autor:
F. Max Yavitt, Bruce E. Kirkpatrick, Michael R. Blatchley, Kelly F. Speckl, Erfan Mohagheghian, Radu Moldovan, Ning Wang, Peter J. Dempsey, Kristi S. Anseth
Publikováno v:
Science Advances. 9
Spatiotemporally coordinated transformations in epithelial curvature are necessary to generate crypt-villus structures during intestinal development. However, the temporal regulation of mechanotransduction pathways that drive crypt morphogenesis rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5758abd54ce88927c015df8957a5decd
https://doi.org/10.1126/sciadv.add5668
https://doi.org/10.1126/sciadv.add5668
Publikováno v:
ACS Biomater Sci Eng
Intestinal organoids are self-organized tissue constructs, grown in vitro, that resemble the structure and function of the intestine and are often considered promising as a prospective platform for drug testing and disease modeling. Organoid developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f6818f6170d0860e6e36ae76b0ca2a
https://pubmed.ncbi.nlm.nih.gov/35298149
https://pubmed.ncbi.nlm.nih.gov/35298149
Autor:
Sharon Gerecht, Rafael Vazquez-Duhalt, Michael R. Blatchley, Dimitris Ntekoumes, Hyunwoo Cho, Franklyn Hall, Vidur Kailash
Publikováno v:
Advanced Science
Advanced Science, Vol 8, Iss 14, Pp n/a-n/a (2021)
Advanced Science, Vol 8, Iss 14, Pp n/a-n/a (2021)
With the increased realization of the effect of oxygen (O2) deprivation (hypoxia) on cellular processes, recent efforts have focused on the development of engineered systems to control O2 concentrations and establish biomimetic O2 gradients to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4123044af149d75a61e02d097760237
http://europepmc.org/articles/PMC8292886
http://europepmc.org/articles/PMC8292886
Publikováno v:
Adv Drug Deliv Rev
In recent years, as the mechanisms of vasculogenesis and angiogenesis have been uncovered, the functions of various pro-angiogenic growth factors (GFs) and cytokines have been identified. Therefore, therapeutic angiogenesis, by delivery of GFs, has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4ee6e756c022df92d6cf29955f7c32
https://doi.org/10.1016/j.addr.2019.08.005
https://doi.org/10.1016/j.addr.2019.08.005
Autor:
Alexandra N. Borelli, Mark W. Young, Bruce E. Kirkpatrick, Matthew W. Jaeschke, Sarah Mellett, Seth Porter, Michael R. Blatchley, Varsha V. Rao, Balaji V. Sridhar, Kristi S. Anseth
Publikováno v:
Advanced Healthcare Materials. 11:2270082
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71c033fcf148f3142422069050a7edd8
https://doi.org/10.1002/adhm.202270082
https://doi.org/10.1002/adhm.202270082
Autor:
Michael R. Blatchley, Kemal Arda Günay, F. Max Yavitt, Elijah M. Hawat, Peter J. Dempsey, Kristi S. Anseth
Publikováno v:
Adv Mater
3D organoid models have recently seen a boom in popularity, as they can better recapitulate the complexity of multicellular organs compared to other in vitro culture systems. However, organoids are difficult to image because of the limited penetratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77a812d16fc999351b31355e2b02de5
https://doi.org/10.1002/adma.202109252
https://doi.org/10.1002/adma.202109252
Publikováno v:
Nature Protocols. 12:1620-1638
Oxygen (O2) acts as a potent upstream regulator of cell function. In both physiological and pathophysiological microenvironments, the O2 concentration is not uniformly distributed but instead follows a gradient that depends on distance from oxygen-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0602d1f463c173050f5656816c37e98b
https://doi.org/10.1038/nprot.2017.059
https://doi.org/10.1038/nprot.2017.059