Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Michael R. Beard"'
Autor:
Emily N. Kirby, Xavier B. Montin, Timothy P. Allen, Jaslan Densumite, Brooke N. Trowbridge, Michael R. Beard
Publikováno v:
Innate Immunity, Vol 30 (2024)
Interferon Stimulated Gene (ISG) expression plays a key role in the control of viral replication and development of a robust adaptive response. Understanding this dynamic relationship between the pathogen and host is critical to our understanding of
Externí odkaz:
https://doaj.org/article/70a7b7d456a945fc85b6e882e421f826
Autor:
Rosa C Coldbeck-Shackley, Ornella Romeo, Sarah Rosli, Linden J Gearing, Jodee A Gould, San S Lim, Kylie H Van der Hoek, Nicholas S Eyre, Byron Shue, Sarah A Robertson, Sonja M Best, Michelle D Tate, Paul J Hertzog, Michael R Beard
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1010843 (2023)
The immunological surveillance factors controlling vulnerability of the female reproductive tract (FRT) to sexually transmitted viral infections are not well understood. Interferon-epsilon (IFNɛ) is a distinct, immunoregulatory type-I IFN that is co
Externí odkaz:
https://doaj.org/article/5466e29dbea44bb9bb2a994a75c3a117
Autor:
Alison E. Roennfeldt, Timothy P. Allen, Brooke N. Trowbridge, Michael R. Beard, Murray L. Whitelaw, Darryl L. Russell, David C. Bersten, Daniel J. Peet
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1545 (2023)
The Hypoxia Inducible Factor (HIF) transcription factors are imperative for cell adaption to low oxygen conditions and development; however, they also contribute to ischaemic disease and cancer. To identify novel genetic regulators which target the H
Externí odkaz:
https://doaj.org/article/5f7d3c25910f4009a1c3622e2ba96cc1
Autor:
Feargal J. Ryan, Christopher M. Hope, Makutiro G. Masavuli, Miriam A. Lynn, Zelalem A. Mekonnen, Arthur Eng Lip Yeow, Pablo Garcia-Valtanen, Zahraa Al-Delfi, Jason Gummow, Catherine Ferguson, Stephanie O’Connor, Benjamin A. J. Reddi, Pravin Hissaria, David Shaw, Chuan Kok-Lim, Jonathan M. Gleadle, Michael R. Beard, Simon C. Barry, Branka Grubor-Bauk, David J. Lynn
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID-19) pandemic. It is increasingly clear that recovered individuals,
Externí odkaz:
https://doaj.org/article/d97cb46895544c47b7dffc3dd1e30ee2
Publikováno v:
Viruses, Vol 15, Iss 5, p 1102 (2023)
Dengue virus (DENV) non-structural protein 1 (NS1) is involved in multiple aspects of the DENV lifecycle. Importantly, it is secreted from infected cells as a hexameric lipoparticle that mediates vascular damage that is a hallmark of severe dengue. A
Externí odkaz:
https://doaj.org/article/7ba6ccf4aeff4a22b60135c06350c8a0
Publikováno v:
Viruses, Vol 13, Iss 11, p 2157 (2021)
Understanding the dynamic relationship between viral pathogens and cellular host factors is critical to furthering our knowledge of viral replication, disease mechanisms and development of anti-viral therapeutics. CRISPR genome editing technology has
Externí odkaz:
https://doaj.org/article/0448a9574aec439fa47a55d0b5cb1589
Autor:
Kylie H. Van der Hoek, Nicholas S. Eyre, Byron Shue, Onruedee Khantisitthiporn, Kittirat Glab-Ampi, Jillian M. Carr, Matthew J. Gartner, Lachlan A. Jolly, Paul Q. Thomas, Fatwa Adikusuma, Tanja Jankovic-Karasoulos, Claire T. Roberts, Karla J. Helbig, Michael R. Beard
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Zika virus (ZIKV) infection has emerged as a global health threat and infection of pregnant women causes intrauterine growth restriction, spontaneous abortion and microcephaly in newborns. Here we show using biologically relevant cells of ne
Externí odkaz:
https://doaj.org/article/31b52a34fd5a49c7bd204c6693170547
Publikováno v:
Vaccines, Vol 8, Iss 3, p 530 (2020)
Zika Virus (ZIKV) and Dengue Virus (DENV) are related viruses of the Flavivirus genus that cause significant disease in humans. Existing control measures have been ineffective at curbing the increasing global incidence of infection for both viruses a
Externí odkaz:
https://doaj.org/article/fa5bf2026f444b388746c66b6a16c489
Autor:
Karla J. Helbig, Rowena A. Bull, Rebecca Ambrose, Michael R. Beard, Helen Blanchard, Till Böcking, Brendon Chua, Agathe M. G. Colmant, Keaton M. Crosse, Damian F. J. Purcell, Johanna Fraser, Joshua A. Hayward, Stuart T. Hamilton, Matloob Husain, Robin MacDiarmid, Jason M. Mackenzie, Gregory W. Moseley, Thi H. O. Nguyen, Miguel E. Quiñones-Mateu, Karl Robinson, Chaturaka Rodrigo, Julio Rodriguez-Andres, Penny A. Rudd, Anja Werno, Peter White, Paul Young, Peter Speck, Merilyn Hibma, Heidi E. Drummer, Gilda Tachedjian
Publikováno v:
Viruses, Vol 12, Iss 6, p 621 (2020)
The Australasian Virology Society (AVS) aims to promote, support and advocate for the discipline of virology in the Australasian region. The society was incorporated in 2011 after 10 years operating as the Australian Virology Group (AVG) founded in 2
Externí odkaz:
https://doaj.org/article/6e907b1a42ed4dc9a447293a0e35a8b4
Autor:
Chuan Kok Lim, Ornella Romeo, Andrew P Chilver, Bang Manh Tran, Dustin J Flanagan, Emily N Kirby, James Breen, Elizabeth Vincan, Nadia Warner, Erin M McCartney, Mark B Van Der Hoek, Andrew Ruszkiewicz, Edmund Tse, Michael R Beard
Background & AimsCurrent HBVin vitromodel systems suffer from many physiological limitations that restrict understanding of complex viral-host interactions and thus prohibit prediction of diseasein vivo. We developed and assessed adult stem cell (AdS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::401a2f7a9b5309afeddbf626642a4a12
https://doi.org/10.1101/2022.10.20.513112
https://doi.org/10.1101/2022.10.20.513112