Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Michael R Steele"'
Autor:
Kevin T Breen, Sarah R Anderson, Michael R Steele, David J Calkins, Alejandra Bosco, Monica L Vetter
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Neurodegeneration in glaucoma results in decline and loss of retinal ganglion cells (RGCs), and is associated with activation of myeloid cells such as microglia and macrophages. The chemokine fractalkine (FKN or Cx3cl1) mediates communication from ne
Externí odkaz:
https://doaj.org/article/6be63ddc9aba4e128bfb3400c54d959b
Autor:
Alejandra Bosco, Samuel D Crish, Michael R Steele, Cesar O Romero, Denise M Inman, Philip J Horner, David J Calkins, Monica L Vetter
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43602 (2012)
Glaucoma is a neurodegenerative disease that results in the progressive decline and ultimate death of retinal ganglion cells (RGCs). While multiple risk factors are associated with glaucoma, the mechanisms leading to onset and progression of the dise
Externí odkaz:
https://doaj.org/article/3a10033f1acd459c89a9afb505aa51fa
Autor:
Cesar O. Romero, Michael R. Steele, Sarah R. Anderson, Amanda G. Kautzman, Monica L. Vetter, Jianmin Zhang, Dorothy P. Schafer
Publikováno v:
The Journal of Neuroscience. 39:2025-2040
Microglia play important roles in shaping the developing CNS, and at early stages they have been proposed to regulate progenitor proliferation, differentiation, and neuronal survival. However, these studies reveal contradictory outcomes, highlighting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67ac992fe02308e577a2c189bf61c72
https://doi.org/10.1523/jneurosci.1854-18.2018
https://doi.org/10.1523/jneurosci.1854-18.2018
Glial coverage in the optic nerve expands in proportion to optic axon loss in chronic mouse glaucoma
Autor:
Sarah R. Anderson, Monica L. Vetter, Alejandra Bosco, Kevin T. Breen, Michael R. Steele, David J. Calkins
Publikováno v:
Experimental Eye Research. 150:34-43
Within the white matter, axonal loss by neurodegeneration is coupled to glial cell changes in gene expression, structure and function commonly termed gliosis. Recently, we described the highly variable expansion of gliosis alebosco@neuro.utah.edu in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b24bd70f460a05f61ff9b08315f643
https://doi.org/10.1016/j.exer.2016.01.014
https://doi.org/10.1016/j.exer.2016.01.014
Autor:
Alejandra Bosco, Michael R. Steele, Cesar O. Romero, William W. Hauswirth, Sanford L. Boye, Kevin T. Breen, Vince A. Chiodo, Sarah R. Anderson, Stephen Tomlinson, Monica L. Vetter
Dysregulation of the complement system is implicated in neurodegeneration, including human and animal glaucoma. Optic nerve and retinal damage in glaucoma is preceded by local complement upregulation and activation, but whether targeting this early i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1ea28ca67073736646c85b51a0105c
https://doi.org/10.1101/369181
https://doi.org/10.1101/369181
Autor:
Michael R. Steele
The Notre Dame Fighting Irish is one of the most celebrated teams in college football. It has the second-most victories of all time, eleven national titles, featured seven Heisman Trophy recipients including Paul Hornung and Tim Brown, and won eighte
Autor:
Alejandra Bosco, Cesar O. Romero, Balamurali K. Ambati, Michael R. Steele, Kevin T. Breen, Alexis A. Chagovetz, Monica L. Vetter
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 5, Pp 443-455 (2015)
Disease Models & Mechanisms
Disease Models & Mechanisms
Microglia serve key homeostatic roles, and respond to neuronal perturbation and decline with a high spatiotemporal resolution. The course of all chronic CNS pathologies is thus paralleled by local microgliosis and microglia activation, which begin at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7e6a8fedf3239d85077995ab84464f
https://doi.org/10.1242/dmm.018788
https://doi.org/10.1242/dmm.018788
Autor:
Jacqueline M. Roberts, Issam Aldiri, Michael R. Steele, Kathryn B. Moore, Mary A. Logan, Monica L. Vetter
Publikováno v:
Developmental biology. 437(1)
Neural basic helix-loop helix (bHLH) transcription factors promote progenitor cell differentiation by activation of downstream target genes that coordinate neuronal differentiation. Here we characterize a neural bHLH target gene in Xenopus laevis, ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cd5adda7ad2fef97c524ff625514bf
https://pubmed.ncbi.nlm.nih.gov/29518376
https://pubmed.ncbi.nlm.nih.gov/29518376
Autor:
Alejandra Bosco, William W. Hauswirth, Sarah R. Anderson, V. Chiodo, Kevin T. Breen, Cesar O. Romero, Sanford L. Boye, Michael R. Steele, Monica L. Vetter, Stephen Tomlinson
Publikováno v:
Acta Ophthalmologica. 95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce7f0da58d9f7d6b7d9da9626fd65b87
https://doi.org/10.1111/j.1755-3768.2017.03621
https://doi.org/10.1111/j.1755-3768.2017.03621
Autor:
Alejandra Bosco, Kevin T. Breen, Monica L. Vetter, Michael R. Steele, David J. Calkins, Sarah R. Anderson
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Frontiers in Neuroscience
Frontiers in Neuroscience
Neurodegeneration in glaucoma results in decline and loss of retinal ganglion cells (RGCs), and is associated with activation of myeloid cells such as microglia and macrophages. The chemokine fractalkine (FKN or Cx3cl1) mediates communication from ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b88e7643b1c7337ba3a891856c6619
http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00526/full
http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00526/full