Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Michael R Shurin"'
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156095 (2016)
Nerve endings are often identified within solid tumors, but their impact on the tumor growth and progression remains poorly understood. Emerging data suggests that the central nervous system may affect cancer development and spreading via the hypotha
Externí odkaz:
https://doaj.org/article/daabf040b6104965874643854f9fcdac
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56886 (2013)
Paclitaxel (Pac) is an antitumor agent that is widely used for treatment of solid cancers. While being effective as a chemotherapeutic agent, Pac in high doses is neurotoxic, specifically targeting sensory innervations. In view of these toxic effects
Externí odkaz:
https://doaj.org/article/a359b9eee8934eb7b63ed93c687571f3
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
The lungs are a key organ in the respiratory system. They are regulated by a complex network of nerves that control their development, structure, function, and response to various pathological stimuli. Accumulating evidence suggests the involvement o
Externí odkaz:
https://doaj.org/article/a1b5f51fcad84366a5a983f847e64234
Autor:
Michael R. Shurin, Viktor Umansky
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
Tumor-associated hypoxia plays an important role in carcinogenesis and metastasis. The expression, activation, and stabilization of hypoxia-inducible transcription factors (HIFs) support malignant cell survival, proliferation, plasticity, and motilit
Externí odkaz:
https://doaj.org/article/28a5ca611e4149ab9cd19121cf851da5
Publikováno v:
Cells, Vol 11, Iss 22, p 3541 (2022)
Nerve-cancer crosstalk resulting in either tumor neurogenesis or intratumoral neurodegeneration is critically controlled by Schwann cells, the principal glial cells of the peripheral nervous system. Though the direct stimulating effect of Schwann cel
Externí odkaz:
https://doaj.org/article/37bd44cded384cf5a8593c23967060c7
Autor:
Sarah E. Wheeler, Galina V. Shurin, Mary Yost, Adam Anderson, Lisa Pinto, Alan Wells, Michael R. Shurin
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
ABSTRACT Knowledge about development and duration of virus-specific antibodies after COVID-19 vaccination is important for understanding how to limit the pandemic via vaccination in different populations and societies. However, the clinical utility o
Externí odkaz:
https://doaj.org/article/410a73f3d2b14cb79a77bd22d7993833
Publikováno v:
American Journal of Clinical Pathology. 159:10-13
Objectives There is concern that the anti–severe acute respiratory syndrome coronavirus 2 therapeutic monoclonal antibodies, used as preexposure prophylaxis in patients with multiple myeloma, may appear as a detectable monoclonal protein by electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da3cd13836751f5ca6a0c6a9ac6c8ca
https://doi.org/10.1093/ajcp/aqac137
https://doi.org/10.1093/ajcp/aqac137
Autor:
Lingqing Xu, Joshua Doyle, Dominique J. Barbeau, Valerie Le Sage, Alan Wells, W. Paul Duprex, Michael R. Shurin, Sarah E. Wheeler, Anita K. McElroy
Publikováno v:
Pathogens, Vol 10, Iss 6, p 710 (2021)
Seroprevalence studies are important for understanding the dynamics of local virus transmission and evaluating community immunity. To assess the seroprevalence for SARS-CoV-2 in Allegheny County, an urban/suburban county in Western PA, 393 human bloo
Externí odkaz:
https://doaj.org/article/8806534ca18745f9823238fdb73a0a0a
Publikováno v:
Cells, Vol 10, Iss 2, p 454 (2021)
Surgery remains an essential therapeutic approach for most solid malignancies. Although for more than a century accumulating clinical and experimental data have indicated that surgical procedures themselves may promote the appearance and progression
Externí odkaz:
https://doaj.org/article/5844393fda0f481db49a6789c1fc31a5
Autor:
Dimitrios Korentzelos, Vandana Baloda, Yujung Jung, Bradley Wheeler, Michael R Shurin, Sarah E Wheeler
Publikováno v:
American Journal of Clinical Pathology. 158:162-166
Objectives Acute viral infections and some vaccines have been shown to increase false positivity in serologic assays. We assessed if the messenger RNA coronavirus disease 2019 (COVID-19) vaccines could cause false reactivity in common serologic assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548afe75fa1acbfffce5414edef29cdb
https://doi.org/10.1093/ajcp/aqac025
https://doi.org/10.1093/ajcp/aqac025