Zobrazeno 1 - 10
of 364
pro vyhledávání: '"Michael R Rose"'
Publikováno v:
BMJ Neurology Open, Vol 3, Iss 1 (2021)
Introduction This short article summarises findings about reduced physical activity of adults with progressive muscle disease as a result of COVID-19 lockdown.Methods As part of an ongoing longitudinal cohort study, we prospectively and objectively m
Externí odkaz:
https://doaj.org/article/4ba017a5e62b4a15850547ae6cb599a7
Autor:
Grant A Rutledge, Larry G Cabral, Brandon J Kuey, Joshua D Lee, Laurence D Mueller, Michael R Rose
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240132 (2020)
Our intuitive understanding of adaptation by natural selection is dominated by the power of selection at early ages in large populations. Yet, as the forces of natural selection fall with adult age, we expect adaptation to be attenuated with age. Exp
Externí odkaz:
https://doaj.org/article/ecdee3da127143ca984bb710e773b51b
Autor:
Mark A Phillips, Grant A Rutledge, James N Kezos, Zachary S Greenspan, Andrew Talbott, Sara Matty, Hamid Arain, Laurence D Mueller, Michael R Rose, Parvin Shahrestani
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Background Studies combining experimental evolution and next-generation sequencing have found that adaptation in sexually reproducing populations is primarily fueled by standing genetic variation. Consequently, the response to selection is r
Externí odkaz:
https://doaj.org/article/1fbd69b2af174bd7a00086fdf4a06cf6
Autor:
Inês Fragata, Pedro Simões, Miguel Lopes-Cunha, Margarida Lima, Bárbara Kellen, Margarida Bárbaro, Josiane Santos, Michael R Rose, Mauro Santos, Margarida Matos
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96227 (2014)
The roles of history, chance and selection have long been debated in evolutionary biology. Though uniform selection is expected to lead to convergent evolution between populations, contrasting histories and chance events might prevent them from attai
Externí odkaz:
https://doaj.org/article/f9e69ced5c15472aa8c39d4f0be13de0
Autor:
Kennedy Matsagas, David B Lim, Marc Horwitz, Cristina L Rizza, Laurence D Mueller, Bryant Villeponteau, Michael R Rose
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6578 (2009)
Small invertebrate animals, such as nematodes and fruit flies, are increasingly being used to test candidate drugs both for specific therapeutic purposes and for long-term health effects. Some of the protocols used in these experiments feature such e
Externí odkaz:
https://doaj.org/article/8b20493506af496c9bbe42b448f7e836
Autor:
Theodore Garland, Michael R. Rose
Experimental approaches to evolution provide indisputable evidence of evolution by directly observing the process at work. Experimental evolution deliberately duplicates evolutionary processes—forcing life histories to evolve, producing adaptations
Publikováno v:
Disability and Rehabilitation. 44:7312-7320
Purpose Measuring the physical activity of adults with progressive muscle diseases is important to inform clinical practice, for activity recommendations and for outcomes meaningful to participants in clinical trials. Despite its wide use, the measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d56ffb8699bbe696ddf71929879277
https://doi.org/10.1080/09638288.2021.1983042
https://doi.org/10.1080/09638288.2021.1983042
Autor:
Michael N Le, Linsey Bui, Howard J Phang, Laurence D. Mueller, Mahtab Jafari, Michael R. Rose, Grant A. Rutledge
Publikováno v:
Rejuvenation Research. 24:331-344
Healthspan science aims to add healthy, functional years to human life. Many different methods of improving healthspan have been investigated, chiefly focusing on just one aspect of an organism's health such as survival. Studies in Drosophila melanog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c631d0a74a0e3e0b69ec6806b47a6ff
https://doi.org/10.1089/rej.2020.2361
https://doi.org/10.1089/rej.2020.2361
Autor:
James N. Kezos, Thomas T. Barter, Mark A. Phillips, Larry G. Cabral, Zachary S. Greenspan, Kenneth R. Arnold, Grigor Azatian, José Buenrostro, Punjot S. Bhangoo, Annie Khong, Gabriel T. Reyes, Adil Rahman, Laura A. Humphrey, Timothy J. Bradley, Laurence D. Mueller, Michael R. Rose
Publikováno v:
Physiological and Biochemical Zoology. :000-000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d7d4b3a7e473161486d3f42d70f310e
https://doi.org/10.1086/724827
https://doi.org/10.1086/724827
Autor:
Benjamin L Mazer, Michael R Rose
Publikováno v:
BMJ. :p1063
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8074e6f803004323005d46d2f7ad0e86
https://doi.org/10.1136/bmj.p1063
https://doi.org/10.1136/bmj.p1063