Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Michael R Odom"'
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 4, p 154 (2024)
Background: Diabetic bladder dysfunction (DBD) is driven in part by inflammation which dysregulates prostaglandin release in the bladder. Precise inflammatory mechanisms responsible for such dysregulation have been elusive. Since prostaglandins impac
Externí odkaz:
https://doaj.org/article/115df09a5c39451dbc4ea60a3b5baca7
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Diabetes is a rapidly expanding epidemic projected to affect as many as 1 in 3 Americans by 2050. This disease is characterized by devastating complications brought about high glucose and metabolic derangement. The most common of these complications
Externí odkaz:
https://doaj.org/article/876c33714b004b2e9e9276e1a58b8da8
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2821 (2023)
Anecdotal evidence has long suggested that patients with lower urinary tract symptoms (LUTS) develop mood disorders, such as depression and anxiety, at a higher rate than the general population and recent prospective studies have confirmed this link.
Externí odkaz:
https://doaj.org/article/29f1c996f44248f1a18ee9626afea96a
Publikováno v:
American Journal of Physiology-Renal Physiology. 323:F616-F632
Approximately half of the patients with diabetes develop diabetic bladder dysfunction (DBD). The initiation and progression of DBD is largely attributed to inflammation due to dysregulated glucose and the production of toxic metabolites that activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fedf2fded366e9ad9bafeb497c55d5
https://doi.org/10.1152/ajprenal.00047.2022
https://doi.org/10.1152/ajprenal.00047.2022
Autor:
Francis M. Hughes, Armand Allkanjari, Michael R. Odom, Jack E. Mulcrone, Huixia Jin, J. Todd Purves
Publikováno v:
American Journal of Physiology-Renal Physiology.
Diabetic Bladder Dysfunction (DBD) is a prevalent diabetic complication that is recalcitrant to glucose control. Using the Akita mouse model (type 1) bred to be NLRP3+/+ or NLRP3-/-, we previously found that females (mild hyperglycemia) progress from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28893c5a45124d42357f32a34429f175
https://doi.org/10.1152/ajprenal.00284.2022
https://doi.org/10.1152/ajprenal.00284.2022
Publikováno v:
Neurourol Urodyn
AIMS Detrusor underactivity (DU) is an understudied health concern with inadequate clinical management. The pathophysiology of DU is unclear, and current therapies fail to improve symptoms. The current studies characterized voiding function and contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19a83a0b905ece612854b54e49ec1c6
https://doi.org/10.1002/nau.24777
https://doi.org/10.1002/nau.24777
Publikováno v:
American family physician. 106(1)
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to gluten-containing grains such as wheat, barley, and rye. The condition can develop at any age. Celiac disease presents with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1a4778344c80d1675837d16634b5906
https://pubmed.ncbi.nlm.nih.gov/35839368
https://pubmed.ncbi.nlm.nih.gov/35839368
Autor:
Kathleen A. Ashcraft, Elena S. Pak, Bridget F. Koontz, Johanna L. Hannan, Shelby A. Powers, Alexander C Turner, Michael R. Odom
Publikováno v:
Neurourol Urodyn
AIMS To determine the effect of prostatic radiation therapy (RT) on bladder contractility and morphology, and axon, or neuron profiles within the detrusor and major pelvic ganglia (MPG) in male rats. METHODS Male Sprague-Dawley rats (8 weeks) receive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2100c0d1b8022e105a24aa8e1a41c97
https://doi.org/10.1002/nau.24705
https://doi.org/10.1002/nau.24705
Publikováno v:
Life Sci
AIMS: Diabetic bladder dysfunction (DBD) is a prevalent diabetic complication thought to progress from overactive (OAB) to underactive (UAB) bladder. Previously we found OAB at 15 weeks in the Akita mouse, a genetic model of Type 1 diabetes. The firs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7f074421f381808cc3cc91dc49e814
https://pubmed.ncbi.nlm.nih.gov/35381220
https://pubmed.ncbi.nlm.nih.gov/35381220
Publikováno v:
Exp Biol Med (Maywood)
Inflammation is a central process in most benign bladder disorders, and its control is a delicate balance between initiating factors and resolving factors. While recent discoveries have shown a central role for the NLRP3 inflammasome in initiation, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9be797cc16988d713e98b07ea720a6b
https://europepmc.org/articles/PMC9039492/
https://europepmc.org/articles/PMC9039492/
