Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Michael R Odom"'
Publikováno v:
Continence, Vol 12, Iss , Pp 101690- (2024)
Aim:: Diabetic bladder dysfunction (DBD) is the most common diabetic complication. Patients present with overactive symptoms, underactive symptoms, or both. While strict glucose control may be expected to reverse DBD, prior studies have not been supp
Externí odkaz:
https://doaj.org/article/1f571337163148d5a08a726dc4aaafcf
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 4, p 154 (2024)
Background: Diabetic bladder dysfunction (DBD) is driven in part by inflammation which dysregulates prostaglandin release in the bladder. Precise inflammatory mechanisms responsible for such dysregulation have been elusive. Since prostaglandins impac
Externí odkaz:
https://doaj.org/article/115df09a5c39451dbc4ea60a3b5baca7
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Diabetes is a rapidly expanding epidemic projected to affect as many as 1 in 3 Americans by 2050. This disease is characterized by devastating complications brought about high glucose and metabolic derangement. The most common of these complications
Externí odkaz:
https://doaj.org/article/876c33714b004b2e9e9276e1a58b8da8
Publikováno v:
American Journal of Physiology-Renal Physiology. 323:F616-F632
Approximately half of the patients with diabetes develop diabetic bladder dysfunction (DBD). The initiation and progression of DBD is largely attributed to inflammation due to dysregulated glucose and the production of toxic metabolites that activate
Autor:
Francis M. Hughes, Armand Allkanjari, Michael R. Odom, Jack E. Mulcrone, Huixia Jin, J. Todd Purves
Publikováno v:
American Journal of Physiology-Renal Physiology.
Diabetic Bladder Dysfunction (DBD) is a prevalent diabetic complication that is recalcitrant to glucose control. Using the Akita mouse model (type 1) bred to be NLRP3+/+ or NLRP3-/-, we previously found that females (mild hyperglycemia) progress from
Publikováno v:
Neurourol Urodyn
AIMS Detrusor underactivity (DU) is an understudied health concern with inadequate clinical management. The pathophysiology of DU is unclear, and current therapies fail to improve symptoms. The current studies characterized voiding function and contr
Publikováno v:
American family physician. 106(1)
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to gluten-containing grains such as wheat, barley, and rye. The condition can develop at any age. Celiac disease presents with
Autor:
Kathleen A. Ashcraft, Elena S. Pak, Bridget F. Koontz, Johanna L. Hannan, Shelby A. Powers, Alexander C Turner, Michael R. Odom
Publikováno v:
Neurourol Urodyn
AIMS To determine the effect of prostatic radiation therapy (RT) on bladder contractility and morphology, and axon, or neuron profiles within the detrusor and major pelvic ganglia (MPG) in male rats. METHODS Male Sprague-Dawley rats (8 weeks) receive
Publikováno v:
Life Sci
AIMS: Diabetic bladder dysfunction (DBD) is a prevalent diabetic complication thought to progress from overactive (OAB) to underactive (UAB) bladder. Previously we found OAB at 15 weeks in the Akita mouse, a genetic model of Type 1 diabetes. The firs
Publikováno v:
Exp Biol Med (Maywood)
Inflammation is a central process in most benign bladder disorders, and its control is a delicate balance between initiating factors and resolving factors. While recent discoveries have shown a central role for the NLRP3 inflammasome in initiation, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9be797cc16988d713e98b07ea720a6b
https://europepmc.org/articles/PMC9039492/
https://europepmc.org/articles/PMC9039492/