Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Michael R La Frano"'
Autor:
Yang-le Gao, Jason E. Cournoyer, Bidhan C. De, Catherine L. Wallace, Alexander V. Ulanov, Michael R. La Frano, Angad P. Mehta
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Conversion of heterotrophic organisms into partially or completely autotrophic organisms is primarily accomplished by extensive metabolic engineering and laboratory evolution efforts that channel CO2 into central carbon metabolism. Here, we
Externí odkaz:
https://doaj.org/article/07c95328604d440c834665bbfd930c50
Autor:
Raya I. Boyd, Doha Shokry, Zeeshan Fazal, Brayden C. Rennels, Sarah J. Freemantle, Michael R. La Frano, Gail S. Prins, Zeynep Madak Erdogan, Joseph Irudayaraj, Ratnakar Singh, Michael J. Spinella
Publikováno v:
Toxics, Vol 12, Iss 4, p 232 (2024)
The potential effects of poly- and perfluoroalkyl substances (PFAS) are a recently emergent human and environmental health concern. There is a consistent link between PFAS exposure and cancer, but the mechanisms are poorly understood. Although epidem
Externí odkaz:
https://doaj.org/article/63bec03f1c444472b4882a8ed84927b2
Autor:
Muhammad Musaddiq Shah, Khurshid Ahmad, Sonia Boota, Tor Jensen, Michael R. La Frano, Joseph Irudayaraj
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Endocrine-disrupting chemicals (EDCs) are a class of man-made substances with potential to disrupt the standard function of the endocrine system. These EDCs include phthalates, perchlorates, phenols, some heavy metals, furans, dimethoate, aromatic hy
Externí odkaz:
https://doaj.org/article/4932aa26bcba4e018db9844978fb445c
Autor:
Magdalena A. Maj, Tanvi R. Gehani, Chad Immoos, Mikaelah S. Medrano, Rob K. Fanter, Christine R. Strand, Hunter Glanz, Brian D. Piccolo, Mohammed K. Abo-Ismail, Michael R. La Frano, Rodrigo Manjarín
Publikováno v:
Brain Sciences, Vol 12, Iss 9, p 1193 (2022)
The objective of this study was to investigate the effect of dietary fatty acid (FA) saturation and carbon chain length on brain bile acid (BA) metabolism and neuronal number in a pig model of pediatric NAFLD. Thirty 20-day-old Iberian pigs, pair-hou
Externí odkaz:
https://doaj.org/article/16494241450f4f88a996fbccb785adfc
Autor:
Todd A. Hagobian, Hannah Brunner-Gaydos, Adam Seal, Andrew Schaffner, Chris Kitts, Ryan Hubbard, Steven K. Malin, Michael R. La Frano, Kelly A. Bennion, Suzanne Phelan
Publikováno v:
Contemporary Clinical Trials Communications, Vol 17, Iss , Pp - (2020)
Previous observational studies have shown that the endocrine disrupting chemical bisphenol A (BPA) is associated with type 2 diabetes, but few studies have examined direct effects of BPA on human health. The purpose of this study is to determine whet
Externí odkaz:
https://doaj.org/article/efacb2ede27746559693d34ebd1f2006
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244013 (2020)
The generation of large metabolomic data sets has created a high demand for software that can fit statistical models to one-metabolite-at-a-time on hundreds of metabolites. We provide the %polynova_2way macro in SAS to identify metabolites differenti
Externí odkaz:
https://doaj.org/article/34d2ebc1e2124a79afde0e6eeb2380a7
Autor:
Rodrigo Manjarín, Kayla Dillard, Morgan Coffin, Gabriella V. Hernandez, Victoria A. Smith, Trista Noland-Lidell, Tanvi R. Gehani, Hayden J. Smart, Kevin Wheeler, Kimberly A. Sprayberry, Mark S. Edwards, Rob K. Fanter, Hunter Glanz, Chad Immoos, Tasha M. Santiago-Rodriguez, Jason M. Blank, Douglas G. Burrin, Brian D. Piccolo, Mohammed Abo-Ismail, Michael R. La Frano, Magdalena Maj
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 323:E187-E206
Bile acid homeostasis and signaling is disrupted in NAFLD and may play a central role in the development of the disease. However, there are no studies addressing the impact of diet on bile acid metabolism in patients with NAFLD. In juvenile Iberian p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9409215551125882f27e6611a4155a4f
https://doi.org/10.1152/ajpendo.00052.2022
https://doi.org/10.1152/ajpendo.00052.2022
Autor:
Jingzhuo Tian, Jingjing Zhu, Yan Yi, Chunying Li, Yushi Zhang, Yong Zhao, Chen Pan, Shixie Xiang, Xiaolong Li, Guiqin Li, John W Newman, Xiaoyi Feng, Jing Liu, Jiayin Han, Lianmei Wang, Yue Gao, Michael R. La Frano, Aihua Liang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Fructus Gardenia (FG), containing the major active constituent Geniposide, is widely used in China for medicinal purposes. Currently, clinical reports of FG toxicity have not been published, however, animal studies have shown FG or Geniposid
Externí odkaz:
https://doaj.org/article/9a2bafc487e94da097d5f878413fc998
Autor:
Catherine M, Johnson, Rodrigo, Rosario, Alex, Brito, Karan, Agrawal, Rob, Fanter, Georg, Lietz, Marjorie, Haskell, Reina, Engle-Stone, John W, Newman, Michael R, La Frano
Publikováno v:
Nutrition Research. 104:118-127
Low vitamin A (VA) status is common among lactating women in low-income countries. Lactation has substantial effects on mother's metabolism and VA is required in multiple biological processes, including growth, vision, immunity, and reproduction. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996e2ff588cbbdb39f53dd66f83896b8
https://doi.org/10.1016/j.nutres.2022.05.007
https://doi.org/10.1016/j.nutres.2022.05.007
Autor:
Kristiana Rood, Vanessa Lopez, Michael R. La Frano, Oliver Fiehn, Lubo Zhang, Arlin B. Blood, Sean M. Wilson
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Gestational hypoxia is a risk factor in the development of pulmonary hypertension in the newborn and other sequela, however, the mechanisms associated with the disease remain poorly understood. This review highlights disruption of metabolism by anten
Externí odkaz:
https://doaj.org/article/93ad4f572a3f42d4acb208a4b61ca008