Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michael R L, Stratford"'
Studies of para-quinomethane formation during the tyrosinase-catalyzed oxidation of 4-alkylcatechols
Publikováno v:
ARKIVOC, Vol 2008, Iss 2, Pp 258-267 (2008)
Externí odkaz:
https://doaj.org/article/b073a251e4a449e2a07deb48ab8acda7
Autor:
Blaz, Groselj, Jia-Ling, Ruan, Helen, Scott, Jessica, Gorrill, Judith, Nicholson, Jacqueline, Kelly, Selvakumar, Anbalagan, James, Thompson, Michael R L, Stratford, Sarah J, Jevons, Ester M, Hammond, Cheryl L, Scudamore, Martin, Kerr, Anne E, Kiltie
Publikováno v:
Molecular cancer therapeutics. 17(2)
As the population ages, more elderly patients require radiotherapy-based treatment for their pelvic malignancies, including muscle-invasive bladder cancer, as they are unfit for major surgery. Therefore, there is an urgent need to find radiosensitisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d22abd03cc84dc1e7d1e19115240585c
https://pubmed.ncbi.nlm.nih.gov/28839000
https://pubmed.ncbi.nlm.nih.gov/28839000
Studies of para-quinomethane formation during the tyrosinase-catalyzed oxidation of 4-alkylcatechols
Publikováno v:
ARKIVOC, Vol 2008, Iss 2, Pp 258-267 (2008)
UV-Vis spectroscopy, hplc-mass spectrometry and deuterium-labeling studies demonstrate that 4-alkyl-ortho-quinones cleanly rearrange to the isomeric 2-hydroxy-para-quinomethanes over a period of 10-20 minutes in aqueous buffer. These ortho-quinones a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f14a0603c7ef5b9e460a43338cdefe
https://ora.ox.ac.uk/objects/uuid:1a8471c9-7bb4-466f-aa4c-60458e546d9e
https://ora.ox.ac.uk/objects/uuid:1a8471c9-7bb4-466f-aa4c-60458e546d9e
Autor:
Peter Hoskin, H Phillips, Søren M. Bentzen, Michael R. L. Stratford, Peter Wardman, Lisa K. Folkes, S Jackson
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 51:460-464
Purpose: To test the hypothesis that there is a link between plasma glutathione (GSH) or other antioxidants (uric acid, ascorbate) and the severity of radiation mucositis following radiation treatment of tumors of the head and neck. Patients and Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb122999ee4bb72075d6743fed131cab
https://doi.org/10.1016/s0360-3016(01)01612-1
https://doi.org/10.1016/s0360-3016(01)01612-1
Autor:
S. Ulhaq, Ian J. Stratford, Steven A. Everett, Michael R. L. Stratford, Peter Wardman, Matthew A. Naylor, John Nolan, S. G. Moore, M Jaffar, K. B. Patel
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:113-118
A series of regioisomeric derivatives of a 1-methylindole-4,7-dione were synthesised, substituted with a 2-acetoxybenzoate leaving group linked through the (indol-2-yl)methyl or (indol-3-yl)methyl (or propenyl) positions. Reductive elimination of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e26691adbf29cb6acaf31cdfe1e7ac
https://doi.org/10.1016/s0960-894x(98)00695-7
https://doi.org/10.1016/s0960-894x(98)00695-7
Autor:
Matthew A. Naylor, K. Indira Priyadarsini, Madeleine F. Dennis, Peter Wardman, and Michael R. L. Stratford
Publikováno v:
Journal of the American Chemical Society. 118:5648-5654
The free radical intermediates formed on one-electron reduction of imidazo[1,2-a]quinoxaline N-oxides RB91724 (I), RB90740 (II), and RB93918 (III) were investigated by pulse radiolysis. Reaction with radiolytically-generated CO2•- radical anions pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c64b3724875e73d380c81920e209f3d1
https://doi.org/10.1021/ja953761o
https://doi.org/10.1021/ja953761o
Autor:
K. B. Patel, Michael R. L. Stratford, Peter Wardman, Ian J. Stratford, Steven A. Everett, Matthew A. Naylor, S. Ulhaq, John Nolan, S. G. Moore, M Jaffar
Publikováno v:
ChemInform. 30
A series of regioisomeric derivatives of a 1-methylindole-4,7-dione were synthesised, substituted with a 2-acetoxybenzoate leaving group linked through the (indol-2-yl)methyl or (indol-3-yl)methyl (or propenyl) positions. Reductive elimination of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb61e4874e46700466e5c60085dfada5
https://doi.org/10.1002/chin.199919133
https://doi.org/10.1002/chin.199919133
Autor:
Elizabeth Swann, Borivoj Vojnovic, Christopher J. Moody, Kantital B. Patel, Matthew A. Naylor, Michael R. L. Stratford, Peter Wardman, Steven A. Everett
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b120a0abbe1f35884f4d21965cc06bce
https://doi.org/10.1002/chin.200145033
https://doi.org/10.1002/chin.200145033
Autor:
Peter Wardman, Michael R. L. Stratford, Eleonora Ford, Borivoj Vojnovic, Amanda C. Ferguson, Kantilal B. Patel, Steven A. Everett, Matthew A. Naylor, Alan Mortensen
Publikováno v:
ChemInform. 33
The radical intermediates and the stable products formed on one-electron oxidation of 1-methylindole-3-carbaldehyde oxime 2a were compared with those of 1-methylindole-3-carboxamidine oxime 4a in aqueous solution. The dibromide radical anion generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a95762dbb30cca595b8a43e43ea9e283
https://doi.org/10.1002/chin.200206040
https://doi.org/10.1002/chin.200206040
Autor:
Peter D, Davis, Graeme J, Dougherty, David C, Blakey, Susan M, Galbraith, Gillian M, Tozer, Angela L, Holder, Matthew A, Naylor, John, Nolan, Michael R L, Stratford, David J, Chaplin, Sally A, Hill
Publikováno v:
Cancer research. 62(24)
Physiological differences between tumor and normal vasculature provide a target for drug discovery. In particular, the immature nature of tumor vasculature may render it intrinsically sensitive to disruption by agents affecting the endothelial cell c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e34afc198074e882562c177065bf2d7a
https://pubmed.ncbi.nlm.nih.gov/12499266
https://pubmed.ncbi.nlm.nih.gov/12499266