Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Michael R Botts"'
Autor:
Naomi M Walsh, Michael R Botts, Andrew J McDermott, Sébastien C Ortiz, Marcel Wüthrich, Bruce Klein, Christina M Hull
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007777 (2019)
The majority of invasive human fungal pathogens gain access to their human hosts via the inhalation of spores from the environment into the lung, but relatively little is known about this infectious process. Among human fungal pathogens the most freq
Externí odkaz:
https://doaj.org/article/96e7a6ae9231499f8b7c44a9e0c8c633
Autor:
Robert J Luallen, Aaron W Reinke, Linda Tong, Michael R Botts, Marie-Anne Félix, Emily R Troemel
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005724 (2016)
Microbial pathogens often establish infection within particular niches of their host for replication. Determining how infection occurs preferentially in specific host tissues is a key aspect of understanding host-microbe interactions. Here, we descri
Externí odkaz:
https://doaj.org/article/3af20ab1834947d08f247a7d37c10a1c
Autor:
Marcel Wüthrich, Michael R. Botts, Christina M. Hull, Sébastien C. Ortiz, Bruce S. Klein, Andrew J. McDermott, Naomi M. Walsh
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007777 (2019)
PLoS Pathogens
PLoS Pathogens
The majority of invasive human fungal pathogens gain access to their human hosts via the inhalation of spores from the environment into the lung, but relatively little is known about this infectious process. Among human fungal pathogens the most freq
Publikováno v:
Infection and Immunity. 84:3047-3062
Cryptococcal meningoencephalitis is a fungal infection that predominantly affects immunocompromised patients and is uniformly fatal if left untreated. Timely diagnosis is difficult, and screening or prophylactic measures have generally not been succe
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 6, Iss 9, Pp 2707-2716 (2016)
G3 (Bethesda, Md.), vol 6, iss 9
G3: Genes, Genomes, Genetics, Vol 6, Iss 9, Pp 2707-2716 (2016)
G3 (Bethesda, Md.), vol 6, iss 9
Microsporidia are ubiquitous parasites that infect a wide range of animal hosts, and these fungal-related microbes undergo their entire replicative lifecycle inside of host cells. Despite being widespread in the environment and causing medical and ag
Autor:
John J. Popovich, Michael R. Botts, Emily R. Troemel, Grace Sek, Kathleen A. Estes, Suzannah C. Szumowski
Publikováno v:
Cellular Microbiology. 18:30-45
Many intracellular pathogens co-opt actin in host cells, but little is known about these interactions in vivo. We study the in vivo trafficking and exit of the microsporidian Nematocida parisii, which is an intracellular pathogen that infects intesti
Publikováno v:
Integrative biology : quantitative biosciences from nano to macro. 8(5)
Germination of spores into actively growing cells is a process essential for survival and pathogenesis of many microbes. Molecular mechanisms governing germination, however, are poorly understood in part because few tools exist for evaluating and int
Autor:
Michael R. Botts, Christina M. Hull
Publikováno v:
Current Opinion in Microbiology. 13:437-442
Many human fungal pathogens infect people when they are inhaled as spores. Despite the serious impact of fungal spores on human health, little is known about their basic properties or how they interact with the host. This is particularly true for Cry
Publikováno v:
Animal Reproduction Science. 194:e23
Publikováno v:
Eukaryotic Cell. 8:595-605
Spores are essential particles for the survival of many organisms, both prokaryotic and eukaryotic. Among the eukaryotes, fungi have developed spores with superior resistance and dispersal properties. For the human fungal pathogens, however, relative