Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michael Räß"'
Autor:
Julius Wehrle, Ulrike Philipp, Martina Jolic, Marie Follo, Saskia Hussung, Silvia Waldeck, Max Deuter, Michael Rassner, Jan Braune, Justyna Rawluk, Christine Greil, Cornelius F. Waller, Heiko Becker, Jesús Duque-Afonso, Anna L. Illert, Ralph M. Fritsch, Frank Meiss, Justus Duyster, Nikolas von Bubnoff, Florian Scherer
Publikováno v:
Diagnostics, Vol 10, Iss 8, p 550 (2020)
Background: Circulating tumor DNA (ctDNA) in the blood plasma of cancer patients is an emerging biomarker used across oncology, facilitating noninvasive disease monitoring and genetic profiling at various disease milestones. Digital droplet PCR (ddPC
Externí odkaz:
https://doaj.org/article/e63030888c5d4ece9ce2c4dc54ca2dd8
Autor:
Giovanni Lamanna, Ian Bird, Andreas Petzold, Ari Asmi, Magdalena Brus, Niklas Blomberg, Michael Räß, Rudolf Dimper, Andrew Gotz, Ron Dekker
THE SCIENCE CLUSTERS are EU collaborative projects that were launched in 2019 to link ESFRI and other world-class Research Infrastructures (RIs) to the European Open Science Cloud (EOSC). The main impacts of the Science Clusters’ work programme con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022daa99aee22aea446f509a20cc3352
Autor:
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Cornelius Miething, Uta S. Martens, Khalid Shoumariyeh, Rosa P. Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R. Blazar, Burkhard Becher, Melanie Boerries, Robert Zeiser
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Patients with corticosteroid-refractory acute graft-versus-host disease (aGVHD) have a low one-year survival rate. Identification and validation of novel targetable kinases in patients who experience corticosteroid-refractory-aGVHD may help
Externí odkaz:
https://doaj.org/article/cb63dbf7545c4a79898fb5a39c9842f1
Autor:
Silvia Waldeck, Jan Mitschke, Sebastian Wiesemann, Michael Rassner, Geoffroy Andrieux, Max Deuter, Jurik Mutter, Anne‐Marie Lüchtenborg, Daniel Kottmann, Laurin Titze, Christoph Zeisel, Martina Jolic, Ulrike Philipp, Silke Lassmann, Peter Bronsert, Christine Greil, Justyna Rawluk, Heiko Becker, Lisa Isbell, Alexandra Müller, Soroush Doostkam, Bernward Passlick, Melanie Börries, Justus Duyster, Julius Wehrle, Florian Scherer, Nikolas von Bubnoff
Publikováno v:
Molecular Oncology, Vol 16, Iss 2, Pp 527-537 (2022)
Circulating tumor DNA (ctDNA) has demonstrated great potential as a noninvasive biomarker to assess minimal residual disease (MRD) and profile tumor genotypes in patients with non‐small‐cell lung cancer (NSCLC). However, little is known about its
Externí odkaz:
https://doaj.org/article/4399d10b1bd049f3a353a6cfadf469f6
Autor:
Oliver Eickelberg, Hugo A. Katus, Oliver Puk, Minxuan Sun, Gabriele Möller, Dirk H. Busch, Eva Janas, Jack Favor, Melanie Kahle, Ralph Steinkamp, Wilfried Szymczak, Markus Ollert, Markus F. Scheerer, Susanne Neschen, Andreas Zimmer, Holger Maier, Thure Adler, Valerie Gailus-Durner, Jan Rozman, Ali Önder Yildirim, Claudia Stöger, Tonia Ludwig, Julia Calzada-Wack, Christoph Lengger, Martin Klingenspor, Anja Schrewe, Ingrid L. Vargas Panesso, Sabine M. Hölter, Evelyn Schiller, Monja Willershäuser, Luciana Caminha Afonso, Barbara Fridrich, Beatrix Naton, Michael Räß, Alexander Götz, Christian M. Cohrs, Eckhard Wolf, Jerzy Adamski, Martin Hrabě de Angelis, Anja Hurt, Ildiko Racz, Birgit Rathkolb, Alexander Bohla, Ramona Zeh, Thomas Klopstock, Tanja Klein-Rodewald, Lore Becker, Kateryna Micklich, Frauke Neff, Alexandra Vernaleken, Tobias Stöger, Annemarie Wolff-Muscate, Juan Antonio Aguilar-Pimentel, Dirk Janik, Wolfgang Hans, Cornelia Prehn, Raffi Bekeredjian, Wolfgang Wurst, Susan Marschall, Christoph Höschen, Helmut Fuchs, Heinz Höfler, Lisa Glasl, Lillian Garrett, Anna Dewert, Martin Kistler, Irina Treise, Jochen Graw, Holger Schulz, Johannes Beckers, Marion Horsch
Publikováno v:
Mamm. Genome 23, 611-622 (2012)
Mammalian genome 23(9-10), 611-622 (2012). doi:10.1007/s00335-012-9415-1
Mammalian Genome
Mammalian genome 23(9-10), 611-622 (2012). doi:10.1007/s00335-012-9415-1
Mammalian Genome
Under the label of the German Mouse Clinic (GMC), a concept has been developed and implemented that allows the better understanding of human diseases on the pathophysiological and molecular level. This includes better understanding of the crosstalk b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4c9113cf82c123a12ff3d46acda9d4
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=10697
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=10697
Autor:
Eckhard Wolf, Claudia Stöger, Jerzy Adamski, Melanie Kahle, Hugo A. Katus, Holger Maier, Andreas Zimmer, Alexander Bohla, Valerie Gailus-Durner, Wolfgang Hans, Tonia Ludwig, Kateryna Micklich, Markus Ollert, Beatrix Naton, Michael Räß, Julia Calzada-Wack, Alexander Götz, Martin Kistler, Christian M. Cohrs, Christoph Lengger, Martin Klingenspor, Luciana Caminha Afonso, Irina Treise, Juan Antonio Aguilar-Pimentel, Birgit Rathkolb, Michael Hagn, Wolfgang Wurst, Tanja Klein-Rodewald, Lillian Garrett, Ildiko Racz, Markus F. Scheerer, Oliver Puk, Raffi Bekeredjian, Frauke Neff, Susanne Neschen, Felix Schöfer, Jochen Graw, Gabriele Möller, Ali Önder Yildirim, Susan Marschall, Monja Willershäuser, Ramona Zeh, Anja Schrewe, Lore Becker, Martin Hrabě de Angelis, Sabine M. Hölter, Jan Rozman, Annemarie Wolff-Muscate, Holger Schulz, Johannes Beckers, Marion Horsch, Tobias Stöger, Andras Franko, Evelyn Schiller, Thure Adler, Lisa Glasl, Jack Favor, Ralph Steinkamp, Sibylle Wagner, Thomas Klopstock, Cornelia Prehn, Helmut Fuchs, Dirk H. Busch
Publikováno v:
Genetics Meets Metabolomics ISBN: 9781461416883
The mouse is widely considered as a toolbox for modeling human diseases: mice are easy to handle and breed, there exist inbred strains, and the mouse genome sequence is available. Mutant mouse lines can be generated by different technologies, and sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2731ab37a11246f3266e4d4c2acbcc4
https://doi.org/10.1007/978-1-4614-1689-0_7
https://doi.org/10.1007/978-1-4614-1689-0_7
Autor:
Monika Engelhardt, Gabriele Ihorst, Martin Schumacher, Michael Rassner, Laura Gengenbach, Mandy Möller, Khalid Shoumariyeh, Jakob Neubauer, Juliane Farthmann, Georg Herget, Ralph Wäsch
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-4 (2021)
Abstract Background The standard to ensure utmost cancer treatment is a prerequisite in national cancer plans for comprehensive cancer centers (CCCs) and ensured through multidisciplinary tumor boards (MTBs). Despite these being compulsory for CCCs,
Externí odkaz:
https://doaj.org/article/3a28f9a7c7f646448b7be7ec42fe90f6
Autor:
Michael Rassner, Rebecca Baur, Ralph Wäsch, Mario Schiffer, Johanna Schneider, Andreas Mackensen, Monika Engelhardt
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-7 (2021)
Abstract Background Treatment with proteasome inhibitors like carfilzomib in patients with multiple myeloma (MM) can induce thrombotic microangiopathy (TMA) characterized by neurological symptoms, acute kidney injury, hemolysis and thrombocytopenia.
Externí odkaz:
https://doaj.org/article/4774728989ef4a82ad06deff5036d949
Autor:
Silvia Waldeck, Michael Rassner, Philip Keye, Marie Follo, Dieter Herchenbach, Cornelia Endres, Anne Charlet, Geoffroy Andrieux, Ulrich Salzer, Melanie Boerries, Justus Duyster, Nikolas vonBubnoff
Publikováno v:
Molecular Oncology, Vol 14, Iss 4, Pp 779-794 (2020)
FLT3‐ITD tyrosine kinase inhibitors (TKI) show limited clinical activity in acute myeloid leukemia (AML) due to emerging resistance. TKI resistance is mediated by secondary FLT3‐ITD mutations only in a minority of cases. We hypothesize that the c
Externí odkaz:
https://doaj.org/article/bd63d97f309d4829be7c3c0875737bfc
Autor:
Veronika Riebl, Sandra Maria Dold, Dagmar Wider, Marie Follo, Gabriele Ihorst, Johannes M. Waldschmidt, Johannes Jung, Michael Rassner, Christine Greil, Ralph Wäsch, Monika Engelhardt
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectiveIn clinical trials (CTs), the assessment of minimal residual disease (MRD) has proven to have prognostic value for multiple myeloma (MM) patients. Multiparameter flow cytometry (MFC) and next-generation sequencing are currently used in CTs a
Externí odkaz:
https://doaj.org/article/22ba87e8d4604950ad5bceae64330e70