Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Michael R, Rountree"'
Autor:
Shinji Honda, Tereza Ormsby, Michael R. Rountree, Eric U. Selker, Vincent T Bicocca, William K Storck
Publikováno v:
Nucleic Acids Research
Heterochromatin is a specialized form of chromatin that restricts access to DNA and inhibits genetic processes, including transcription and recombination. In Neurospora crassa, constitutive heterochromatin is characterized by trimethylation of lysine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9b0499844fe6b5a2744e19ff146e14
https://doi.org/10.1093/nar/gkaa724
https://doi.org/10.1093/nar/gkaa724
Publikováno v:
Genetics. 215:569-578
In chromatin, nucleosomes are composed of ∼146 bp of DNA wrapped around a histone octamer, and are highly dynamic structures subject to remodeling and exchange. Histone turnover has previously been implicated in various processes including the regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75083933f87334aeacb6353610921f7e
https://doi.org/10.1534/genetics.120.303217
https://doi.org/10.1534/genetics.120.303217
Autor:
Andrew D Klocko, Michael R Rountree, Paula L Grisafi, Shan M Hays, Keyur K Adhvaryu, Eric U Selker
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005083 (2015)
Heterochromatin and associated gene silencing processes play roles in development, genome defense, and chromosome function. In many species, constitutive heterochromatin is decorated with histone H3 tri-methylated at lysine 9 (H3K9me3) and cytosine m
Externí odkaz:
https://doaj.org/article/8070934beb69440182a1a7bf6de8874a
Autor:
William K, Storck, Sabrina Z, Abdulla, Michael R, Rountree, Vincent T, Bicocca, Eric U, Selker
Publikováno v:
Genetics
In chromatin, nucleosomes are composed of ∼146 bp of DNA wrapped around a histone octamer, and are highly dynamic structures subject to remodeling and exchange. Histone turnover has previously been implicated in various processes including the regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8778d08bb86d5c87a574d1931f32a265
https://pubmed.ncbi.nlm.nih.gov/32357961
https://pubmed.ncbi.nlm.nih.gov/32357961
Autor:
Elizabeth T. Wiles, Michael R. Rountree, Tereza Ormsby, Eric U. Selker, Keyur K. Adhvaryu, Shinji Honda, Miki Uesaka, Andrew D. Klocko
Publikováno v:
Genetics. 211:563-578
In the filamentous fungus Neurospora crassa, constitutive heterochromatin is marked by tri-methylation of histone H3 lysine 9 (H3K9me3) and DNA methylation. We identified mutations in the Neurospora defective in methylation-1 (dim-1) gene that cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc704b615d78d33e33a9d15c542d2bb6
https://doi.org/10.1534/genetics.118.301711
https://doi.org/10.1534/genetics.118.301711
Autor:
Ayaka Kukino, Dmytro Grygoryev, Michael R. Rountree, Matthew P. Butler, Charles N. Allen, Anna Ohlrich, Mitchell S. Turker, Furaha A. Rwatambuga
Publikováno v:
J Biol Rhythms
Mammalian tissues display circadian rhythms in transcription, translation, and histone modifications. Here we asked how an advance of the light-dark cycle alters daily rhythms in the liver epigenome at the H3K4me3 (trimethylation of lysine 4 on histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4d410fe2d99f56ad0c84f6e62b57f7
https://doi.org/10.1177/0748730418779958
https://doi.org/10.1177/0748730418779958
Publikováno v:
Proceedings of the National Academy of Sciences. 110:6027-6032
Trimethylated lysine 27 on histone H3 (H3K27me3) is present in Drosophila, Arabidopsis , worms, and mammals, but is absent from yeasts that have been examined. We identified and analyzed H3K27me3 in the filamentous fungus Neurospora crassa and in oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0010c770c24f0ccbffb3a2078667b70
https://doi.org/10.1073/pnas.1303750110
https://doi.org/10.1073/pnas.1303750110
Autor:
Eun Y Yu, Jeanne M.L. Selker, Ayumi Yokoyama, Vincent T Bicocca, Shinji Honda, Jordan D Gessaman, Michael R. Rountree, Eric U. Selker
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(41)
DNA methylation, heterochromatin protein 1 (HP1), histone H3 lysine 9 (H3K9) methylation, histone deacetylation, and highly repeated sequences are prototypical heterochromatic features, but their interrelationships are not fully understood. Prior wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75eb8783f5af94df4d739ab48e67fb8f
https://pubmed.ncbi.nlm.nih.gov/28137865
https://pubmed.ncbi.nlm.nih.gov/28137865
Publikováno v:
Mutation research. 796
BRCA1 plays an important role in preventing breast cancer and is often silenced or repressed in sporadic cancer. The BRCA1 promoter is bidirectional: it drives transcription of the long non-coding (lnc) NBR2 transcript in the opposite orientation rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd80339d159b0097d2891b422723d13
https://pubmed.ncbi.nlm.nih.gov/28249151
https://pubmed.ncbi.nlm.nih.gov/28249151
Autor:
Michael R. Rountree, Eric U. Selker
Publikováno v:
Heredity. 105:38-44
Studies of the control and function of DNA methylation in Neurospora crassa have led to a greater understanding of heterochromatin formation. DNA methylation in Neurospora is dependent on trimethylation of histone H3 lysine 9 (H3K9me3) by the histone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8caf4466e3fc1e995caba375d5487b
https://doi.org/10.1038/hdy.2010.44
https://doi.org/10.1038/hdy.2010.44