Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Michael R, McNeil"'
Autor:
Bryna L. Fitzgerald, Sebabrata Mahapatra, Delphine K. Farmer, Michael R. McNeil, Robert A. Casero, John T. Belisle
Publikováno v:
ACS Omega, Vol 2, Iss 7, Pp 3921-3930 (2017)
Externí odkaz:
https://doaj.org/article/58f7e897909741748df5d645d4ba5ba2
Autor:
Marie I. Samanovic, Hao-Chi Hsu, Marcus B. Jones, Victoria Jones, Michael R. McNeil, Samuel H. Becker, Ashley T. Jordan, Miroslav Strnad, Changcheng Xu, Mary Jackson, Huilin Li, K. Heran Darwin
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT It was recently reported that the human-exclusive pathogen Mycobacterium tuberculosis secretes cytokinins, which had only been known as plant hormones. While cytokinins are well-established, adenine-based signaling molecules in plants, they
Externí odkaz:
https://doaj.org/article/8cd03f758378472fbebf93b3106723bd
Autor:
Ashutosh Upadhyay, Fabio L. Fontes, Mercedes Gonzalez-Juarrero, Michael R. McNeil, Debbie C. Crans, Mary Jackson, Dean C. Crick
Publikováno v:
ACS Central Science, Vol 1, Iss 6, Pp 292-302 (2015)
Externí odkaz:
https://doaj.org/article/681976f12f8e40828311147cdf875cc4
Publikováno v:
ACS Chem Biol
The arabinogalactan of Corynebacterianeae is a critical heteropolysaccharide that tethers outer membrane mycolic acids to peptidoglycan thus forming the characteristic cell wall core of these prokaryotes. An essential α-(1→5)-arabinosyltransferase
Publikováno v:
Communications Chemistry, Vol 3, Iss 1, Pp 1-15 (2020)
Commun Chem
Commun Chem
Mycobacterial lipoarabinomannan (LAM) is in an essential cell envelope lipopolysaccharide anchored both to the plasma and outer membranes. To understand critical biological questions such as the biosynthesis, spatial organization of LAM within the ce
Autor:
Zuzana Palčeková, Shiva K. Angala, Mary Jackson, Michael R. McNeil, Martine Gilleron, Juan Manuel Belardinelli, Luiz E. Bermudez
Publikováno v:
ACS Infectious Diseases. 6:2235-2248
Lipoarabinomannan (LAM) and its biosynthetic precursors, phosphatidylinositol mannosides (PIMs) and lipomannan (LM) play important roles in the interactions of Mycobacterium tuberculosis with phago...
Autor:
Jiuyu Liu, Richard E. Lee, Victoria Jones, Sourav Das, Michael R. McNeil, Anna E. Grzegorzewicz, Mary Jackson, Clifford T. Gee, Juan Manuel Belardinelli
Publikováno v:
ACS Infectious Diseases. 6:195-204
Isoxyl (ISO) and thiacetazone (TAC) are two antitubercular prodrugs that abolish mycolic acid biosynthesis and kill Mycobacterium tuberculosis (Mtb) through the inhibition of the essential type II fatty acid synthase (FAS-II) dehydratase HadAB. While
Autor:
Claudia M. Boot, Michael R. McNeil, Prithwiraj De, Delphi Chatterjee, Libin Shi, Diane J. Ordway
Publikováno v:
ACS Infect Dis
Mycobacterium tuberculosis lipoarabinomannan (LAM) is a biomarker for active tuberculosis (TB) disease. The presence of LAM in the urine of TB patients, whether HIV positive or negative, has been validated by a gas chromatography/mass spectral method
Autor:
Rakesh, David F Bruhn, Michael S Scherman, Lisa K Woolhiser, Dora B Madhura, Marcus M Maddox, Aman P Singh, Robin B Lee, Julian G Hurdle, Michael R McNeil, Anne J Lenaerts, Bernd Meibohm, Richard E Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87909 (2014)
The reductively activated nitroaromatic class of antimicrobials, which include nitroimidazole and the more metabolically labile nitrofuran antitubercular agents, have demonstrated some potential for development as therapeutics against dormant TB baci
Externí odkaz:
https://doaj.org/article/5a17b56fb20942aa854494bae86ab371
Autor:
Laila Sago, Anna E. Grzegorzewicz, Michael R. McNeil, Mary Jackson, Cécile Labarre, Nicolas Bayan, Nathalie Dautin, Niloofar Mohiman
Publikováno v:
Research in Microbiology
Research in Microbiology, Elsevier, In press, ⟨10.1016/j.resmic.2021.103874⟩
Research in Microbiology, In press, ⟨10.1016/j.resmic.2021.103874⟩
Research in Microbiology, Elsevier, In press, ⟨10.1016/j.resmic.2021.103874⟩
Research in Microbiology, In press, ⟨10.1016/j.resmic.2021.103874⟩
International audience; LppX is an important virulence factor essential for surface localization of phthiocerol dimycocerosates (DIM) in Mycobacterium tuberculosis. Based on Concanavalin A recognition, M. tuberculosis LppX (LppX-tb) was initially pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cc78f0a5b873c451e6edf5813b3488
https://hal.archives-ouvertes.fr/hal-03389123
https://hal.archives-ouvertes.fr/hal-03389123