Zobrazeno 1 - 10
of 431
pro vyhledávání: '"Michael R, Grever"'
Autor:
Nilesh Kapoor, Qiuhong Zhao, Andrew Stiff, Seema A. Bhat, Mirela I. Anghelina, Leslie A. Andritsos, James S. Blachly, Narendranath Epperla, Zeinab El Boghdadly, Michael R. Grever, Kerry A. Rogers
Publikováno v:
eJHaem, Vol 5, Iss 5, Pp 1005-1009 (2024)
Abstract Hairy cell leukemia is an uncommon B‐cell malignancy with excellent response to purine analogs and to targeted therapies such as ibrutinib and vemurafenib. However, purine analogs are known to be highly immunosuppressive and the infection
Externí odkaz:
https://doaj.org/article/d12158607d5649e69991ca098e4e599c
Autor:
Kaitlin Annunzio, Michael Ozga, Ying Huang, Mirela Anghelina, Seema A. Bhat, James S. Blachly, Michael R. Grever, Gerard Lozanski, Jasmine Neal, Polina Shindiapina, Kerry A. Rogers
Publikováno v:
eJHaem, Vol 4, Iss 4, Pp 1200-1202 (2023)
Externí odkaz:
https://doaj.org/article/f5a5e4450cd243178370f7aac4d9c690
Autor:
Nyla A. Heerema, Natarajan Muthusamy, Qiuhong Zhao, Amy S. Ruppert, Heather Breidenbach, Leslie A. Andritsos, Michael R. Grever, Kami J. Maddocks, Jennifer Woyach, Farrukh Awan, Meixiao Long, Amber Gordon, Caitlin Coombes, John C. Byrd
Publikováno v:
Haematologica, Vol 106, Iss 6 (2020)
Mutations of the IGH variable region in patients with chronic lymphocytic leukemia (CLL) are associated with a favorable prognosis. Cytogenetic complexity (>3 unrelated aberrations) and translocations have been associated with an unfavorable prognosi
Externí odkaz:
https://doaj.org/article/c1f8c37f9c954bf6a8dafb620cb0ea2a
Autor:
Yo-Ting Tsai, Aparna Lakshmanan, Amy Lehman, Bonnie K. Harrington, Fabienne McClanahan Lucas, Minh Tran, Ellen J. Sass, Meixiao Long, Alan D. Flechtner, Florinda Jaynes, Krista La Perle, Vincenzo Coppola, Gerard Lozanski, Natarajan Muthusamy, John C. Byrd, Michael R. Grever, David M. Lucas
Publikováno v:
Blood Advances, Vol 1, Iss 24, Pp 2147-2160 (2017)
Abstract: Mutated mitogen-activated protein kinase (MAPK) pathway components promote tumor survival, proliferation, and immune evasion in solid tumors. MAPK mutations occur in hematologic cancers as well, but their role is less clear and few models a
Externí odkaz:
https://doaj.org/article/c6e0f46b0f7340d6824ced467f0fcaeb
Autor:
Cecelia R. Miller, Amy S. Ruppert, Nyla A. Heerema, Kami J. Maddocks, Jadwiga Labanowska, Heather Breidenbach, Gerard Lozanski, Weiqiang Zhao, Amber L. Gordon, Jeffrey A. Jones, Joseph M. Flynn, Samantha M. Jaglowski, Leslie A. Andritsos, Kristie A. Blum, Farrukh T. Awan, Kerry A. Rogers, Michael R. Grever, Amy J. Johnson, Lynne V. Abruzzo, Erin K. Hertlein, James S. Blachly, Jennifer A. Woyach, John C. Byrd
Publikováno v:
Blood Advances, Vol 1, Iss 19, Pp 1584-1588 (2017)
Abstract: Ibrutinib is a highly effective targeted therapy for chronic lymphocytic leukemia (CLL). However, ibrutinib must be discontinued in a subset of patients due to progressive CLL or transformation to aggressive lymphoma (Richter transformation
Externí odkaz:
https://doaj.org/article/a325e38f8d5245adac540764291770ba
Autor:
Pooja S. Kumar, Tracy Wiczer, Lindsay Rosen, Arthur J. Pollauf, Amy Zheng, Marilly Palettas, Leylah Azali, Seema A. Bhat, John C. Byrd, Michael R. Grever, Kerry A. Rogers, Jennifer A. Woyach, Adam S. Kittai
Publikováno v:
Leukemia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::075beca8f338c3db3fc9f625f9db0419
https://doi.org/10.1038/s41375-023-01927-8
https://doi.org/10.1038/s41375-023-01927-8
Autor:
Kristin L Koenig, Prachi Jain, Ying Huang, Kerry A. Rogers, Seema A. Bhat, Jennifer A. Woyach, Michael R. Grever, Uma Borate, Alice S. Mims, Daniel Jones, Cecelia Miller, James S. Blachly, Adam S Kittai
Publikováno v:
Blood. 140:4071-4073
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f15b7a2fef05f9ab2eae3d7abb961a03
https://doi.org/10.1182/blood-2022-168274
https://doi.org/10.1182/blood-2022-168274
Autor:
Isaac Esplin, Ying Huang, Seema A. Bhat, Cara Grantier, Michael R. Grever, Corinne Hoffman, Adam S Kittai, Margaret S. Lucas, Mollie E. Moran, Mark Reid, Swetha Suresh, Jennifer A. Woyach, Kerry A. Rogers
Publikováno v:
Blood. 140:4166-4168
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92a6a3ea35343381d51a364aeeed33f7
https://doi.org/10.1182/blood-2022-167314
https://doi.org/10.1182/blood-2022-167314
Autor:
Mitch A. Phelps, Michael R. Grever, John C. Byrd, Amy J. Johnson, Yuan Zhao, Ming Poi, Amy S. Ruppert, Kristie A. Blum, Diane R. Mould, Jia Ji
Purpose: Flavopiridol, the first clinically evaluated cyclin-dependent kinase inhibitor, shows activity in patients with refractory chronic lymphocytic leukemia, but prevalent and unpredictable tumor lysis syndrome (TLS) presents a major barrier to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f18a6ff9f75be1fbd997bf5a09f0b9e
https://doi.org/10.1158/1078-0432.c.6521337.v1
https://doi.org/10.1158/1078-0432.c.6521337.v1
Autor:
Craig C. Hofmeister, Michael R. Grever, Flavia Pichiorri, Ashley E. Rosko, Yvonne A. Efebera, Don M. Benson, Gregory B. Lesinski, Thomas Mace, Andrew Stiff, Gerard J. Nuovo, Douglas W. Sborov
Purpose: Reolysin, a proprietary isolate of reovirus type III dearing, enters and preferentially induces apoptosis of malignant cells. RAS pathway activation has been associated with more efficient reoviral infectivity and enhanced oncolysis. Reoviru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11979b1ca5f78b7ddf45f7285b2ba50e
https://doi.org/10.1158/1078-0432.c.6523079.v1
https://doi.org/10.1158/1078-0432.c.6523079.v1