Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Michael R, Clay"'
Autor:
Andrew J. Murphy, Changde Cheng, Justin Williams, Timothy I. Shaw, Emilia M. Pinto, Karissa Dieseldorff-Jones, Jack Brzezinski, Lindsay A. Renfro, Brett Tornwall, Vicki Huff, Andrew L. Hong, Elizabeth A. Mullen, Brian Crompton, Jeffrey S. Dome, Conrad V. Fernandez, James I. Geller, Peter F. Ehrlich, Heather Mulder, Ninad Oak, Jamie Maciezsek, Carolyn M. Jablonowski, Andrew M. Fleming, Prahalathan Pichavaram, Christopher L. Morton, John Easton, Kim E. Nichols, Michael R. Clay, Teresa Santiago, Jinghui Zhang, Jun Yang, Gerard P. Zambetti, Zhaoming Wang, Andrew M. Davidoff, Xiang Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Developing synchronous bilateral Wilms tumor suggests an underlying (epi)genetic predisposition. Here, we evaluate this predisposition in 68 patients using whole exome or genome sequencing (n = 85 tumors from 61 patients with matched germlin
Externí odkaz:
https://doaj.org/article/946f460fad5e41959f9465bb4f236137
Autor:
Ali Hakimi, BS, Christina Stuart, MD, Devin Zarkowsky, MD, Michael R. Clay, MD, Jeniann Yi, MD, MSCS
Publikováno v:
Journal of Vascular Surgery Cases and Innovative Techniques, Vol 8, Iss 4, Pp 715-718 (2022)
Carotid blowout (CB) is a life-threatening surgical emergency with a mortality rate of up to 60%. CB is commonly seen in head and neck cancer patients after surgical and radiation therapy; other causes include iatrogenic, traumatic, or infectious eti
Externí odkaz:
https://doaj.org/article/499f6eeb76e64310a0684aa0cabc07c1
Autor:
V. Michael Holers, Rachel M. Frank, Andrew Clauw, Jennifer Seifert, Michael Zuscik, Sakthi Asokan, Christopher Striebich, Michael R. Clay, Larry W. Moreland, Nirmal K. Banda
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Anterior cruciate ligament (ACL) injury and meniscal tear (MT) are major causal factors for developing post-traumatic osteoarthritis (PTOA), but the biological mechanism(s) are uncertain. After these structural damages, the synovium could be affected
Externí odkaz:
https://doaj.org/article/00b8aa3de9c0458f9f8dd0451e8d1d61
Autor:
Michael R. Clay, Anand Patel, Quynh Tran, Dale J. Hedges, Ti-Cheng Chang, Elizabeth Stewart, Greg Charville, Cynthia Cline, Michael A. Dyer, Brent A. Orr
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Rhabdomyosarcomas (RMS) represent a family of aggressive soft tissue sarcomas that present in both children and adults. Pathologic risk stratification for RMS has been based on histologic subtype, with poor outcomes observed in alveolar rhab
Externí odkaz:
https://doaj.org/article/2a65920f1718448eb362b6a801462e28
Autor:
Maged Zeineldin, Sara Federico, Xiang Chen, Yiping Fan, Beisi Xu, Elizabeth Stewart, Xin Zhou, Jongrye Jeon, Lyra Griffiths, Rosa Nguyen, Jackie Norrie, John Easton, Heather Mulder, Donald Yergeau, Yanling Liu, Jianrong Wu, Collin Van Ryn, Arlene Naranjo, Michael D. Hogarty, Marcin M. Kamiński, Marc Valentine, Shondra M. Pruett-Miller, Alberto Pappo, Jinghui Zhang, Michael R. Clay, Armita Bahrami, Peter Vogel, Seungjae Lee, Anang Shelat, Jay F. Sarthy, Michael P. Meers, Rani E. George, Elaine R. Mardis, Richard K. Wilson, Steven Henikoff, James R. Downing, Michael A. Dyer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
In most cancers, mutations that lead to oncogene activation and tumor suppressor inactivation synergize to promote tumorigenesis. However, in neuroblastomas, MYCN amplification and ATRX mutations are mutually exclusive and incompatible.
Externí odkaz:
https://doaj.org/article/08a87c1bf95d4f798e9e0d5a7daabd61
Autor:
Andrew J. Murphy, Xiang Chen, Emilia M. Pinto, Justin S. Williams, Michael R. Clay, Stanley B. Pounds, Xueyuan Cao, Lei Shi, Tong Lin, Geoffrey Neale, Christopher L. Morton, Mary A. Woolard, Heather L. Mulder, Hyea Jin Gil, Jerold E. Rehg, Catherine A. Billups, Matthew L. Harlow, Jeffrey S. Dome, Peter J. Houghton, John Easton, Jinghui Zhang, Rani E. George, Gerard P. Zambetti, Andrew M. Davidoff
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The progress in pre-clinical drug discovery for Wilms tumor (WT) is limited by a lack of disease models. Here, the authors develop 45 heterotopic WT patient-derived xenografts including several anaplastic models that recapitulate the biological heter
Externí odkaz:
https://doaj.org/article/db96314ad7db4fb39fc7295bd2b1e60c
Publikováno v:
Surgical Clinics of North America. 102:637-656
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b73ef81c9955100aea9e271d285a4d38
https://doi.org/10.1016/j.suc.2022.04.006
https://doi.org/10.1016/j.suc.2022.04.006
Senescence-induced immune remodeling facilitates metastatic adrenal cancer in a sex-dimorphic manner
Autor:
Kate M. Warde, Lorenzo J. Smith, Lihua Liu, Chris J. Stubben, Brian K. Lohman, Parker W. Willett, Julia L. Ammer, Guadalupe Castaneda-Hernandez, Sikiru O. Imodoye, Chenge Zhang, Kara D. Jones, Kimber Converso-Baran, H. Atakan Ekiz, Marc Barry, Michael R. Clay, Katja Kiseljak-Vassiliades, Thomas J. Giordano, Gary D. Hammer, Kaitlin J. Basham
Publikováno v:
Nature Aging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2aa39a9d406572a35132f281304625e
https://doi.org/10.1038/s43587-023-00420-2
https://doi.org/10.1038/s43587-023-00420-2
Autor:
Michael P. Ludwig, Matthew D. Galbraith, Neetha Paul. Eduthan, Amanda A. Hill, Michael R. Clay, Cristiam Moreno Tellez, Breelyn A. Wilky, Anthony Elias, Joaquín Maximiliano. Espinosa, Kelly D. Sullivan
Publikováno v:
Cancer Research.
Liposarcoma is the most commonly occurring soft tissue sarcoma and is frequently characterized by amplification of chromosome region 12q13-15 harboring the oncogenes MDM2 and CDK4. This unique genetic profile makes liposarcoma an attractive candidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a54ea5168579523fc47f36426c15039d
https://doi.org/10.1158/0008-5472.can-22-3173
https://doi.org/10.1158/0008-5472.can-22-3173
Autor:
Kim E. Nichols, Jinghui Zhang, James R. Downing, David W. Ellison, Ching-Hon Pui, Liza-Marie Johnson, Giles Robinson, Alberto S. Pappo, Stacy J. Hines-Dowell, Jessica M. Valdez, Leslie M. Taylor, Elsie L. Gerhardt, Roya Mostafavi, Regina Nuccio, Emily A. Quinn, Rose B. McGee, Charles G. Mullighan, Zhaohui Gu, Jian Wang, Alexander M. Gout, Jay Knight, Victor Pastor, Jamie L. Maciaszek, Manish Kubal, Delaram Rahbarinia, Mark R. Wilkinson, Aman Patel, Jared Becksfort, Eric Davis, Manjusha Pande, Ti-Cheng Chang, Xin Zhou, Samuel W. Brady, Yu Liu, Zhaojie Zhang, Yanling Liu, Antonina Silkov, Annastasia Ouma, Michael R. Clay, Lu Wang, Lynn W. Harrison, Jiali Gu, Jeffery M. Klco, Brent A. Orr, Armita Bahrami, Andrew Thrasher, Michael N. Edmonson, Scott G. Foy, Kayla V. Hamilton, Dale J. Hedges, Sheila Shurtleff, Michael Rusch, David A. Wheeler, Elizabeth M. Azzato, Chimene A. Kesserwan, Joy Nakitandwe, Scott Newman
Supplementary Figure S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1967bd812c67530d5a87837dd129084
https://doi.org/10.1158/2159-8290.22540643.v1
https://doi.org/10.1158/2159-8290.22540643.v1
