Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Michael Q Steinman"'
Autor:
George K Todd, Casey A Boosalis, Aaron A Burzycki, Michael Q Steinman, Lynda D Hester, Pete W Shuster, Randen L Patterson
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e58996 (2013)
One of the goals in neuroscience is to obtain tractable laboratory cultures that closely recapitulate in vivo systems while still providing ease of use in the lab. Because neurons can exist in the body over a lifetime, long-term culture systems are n
Externí odkaz:
https://doaj.org/article/916b52d101b544c5a3651e4c466d954c
Autor:
Vittoria Borgonetti, Bryan Cruz, Valentina Vozella, Sophia Khom, Michael Q. Steinman, Ryan Bullard, Shannon D’Ambrosio, Christopher S. Oleata, Roman Vlkolinsky, Michal Bajo, Eric P. Zorrilla, Dean Kirson, Marisa Roberto
Publikováno v:
Cells, Vol 12, Iss 15, p 1943 (2023)
Alcohol use disorder (AUD) and anxiety disorders are frequently comorbid and share dysregulated neuroimmune-related pathways. Here, we used our established rat model of comorbid post-traumatic stress disorder (PTSD)/AUD to characterize the interleuki
Externí odkaz:
https://doaj.org/article/f1ca53bbecf847929d0a2eb987ed9032
Autor:
Dean Kirson, Sarah A. Wolfe, Larry Rodriguez, Michael Q. Steinman, Sophia Khom, Christopher S. Oleata, Marisa Roberto
Publikováno v:
Alcohol. 109:96-97
Autor:
Samantha R. Spierling Bagsic, Michal Bajo, Michael Q. Steinman, Sarah A. Wolfe, Eric P. Zorrilla, Ilhem Messaoudi, Suhas Sureshchandra, Dean Kirson, Christopher S. Oleata, Marisa Roberto
Publikováno v:
J Neurosci Res
Alcohol use disorder (AUD) and affective disorders are frequently comorbid and share underlying mechanisms that could be targets for comprehensive treatment. Post-traumatic stress disorder (PTSD) has high comorbidity with AUD, but comprehensive model
Publikováno v:
Neuroscience Applied. 2:101127
Lactate from astrocytes fuels learning-induced mRNA translation in excitatory and inhibitory neurons
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-11 (2019)
Communications Biology
Communications Biology
Glycogenolysis and lactate transport from astrocytes to neurons is required for long-term memory formation, but the role of this lactate is poorly understood. Here we show that the Krebs cycle substrates pyruvate and ketone body B3HB can functionally
Autor:
David M. Hedges, William B. Kiosses, Amanda J. Roberts, Roman Vlkolinsky, Florence P. Varodayan, Reesha R. Patel, Marisa Roberto, Michal Bajo, Tali Nadav, Michael Q. Steinman, Sophia Khom, Ilham Polis
Publikováno v:
Brain, Behavior, and Immunity. 75:208-219
The interleukin-1 system (IL-1) is a prominent pro-inflammatory pathway responsible for the initiation and regulation of immune responses. Human genetic and preclinical studies suggest a critical role for IL-1β signaling in ethanol drinking and depe
Autor:
Sarah A. Wolfe, Florence P. Varodayan, Roman Vlkolinsky, Marisa Roberto, Reesha R. Patel, Amanda J. Roberts, Ilham Polis, R. Adron Harris, Sarah E. Montgomery, R. Dayne Mayfield, Sophia Khom, Anna S. Warden, Tali Nadav, Michal Bajo, Michael Q. Steinman
Publikováno v:
Biol Psychiatry
Background Microglia, the primary immune cells of the brain, are implicated in alcohol use disorder. However, it is not known if microglial activation contributes to the transition from alcohol use to alcohol use disorder or is a consequence of alcoh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67892320de9a4c974177646bbaf5f0f
https://europepmc.org/articles/PMC7674270/
https://europepmc.org/articles/PMC7674270/
Autor:
M. Adrienne McGinn, Ilhem Messaoudi, Luis A. Natividad, Scott Edwards, Michael Q. Steinman, Suhas Sureshchandra, Tony M. Kerr, Roberto Ciccocioppo, Marisa Roberto
Publikováno v:
Addict Biol
Genetically-selected Marchigian Sardinian alcohol-preferring (msP) rats display comorbid symptoms of increased alcohol preference and elevated anxiety-like behavior. Heightened stress sensitivity in msPs is influenced by genetic polymorphisms of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d093d3f507b6e91b8c9b3adeab114e39
http://hdl.handle.net/11581/447407
http://hdl.handle.net/11581/447407
Autor:
Samantha R. Spierling Bagsic, Christopher S. Oleata, Suhas Sureshchandra, Noah K Hoang, Roman Vlkolinský, Sophia Khom, Dean Kirson, Anshita Singhal, Marisa Roberto, Michael Q. Steinman, Ilhem Messaoudi, Eric P. Zorrilla, Sarah A. Wolfe, Michal Bajo, Shannon R. D'Ambrosio
Publikováno v:
Molecular psychiatry
Alcohol use disorder (AUD) and anxiety disorders are frequently comorbid and share mechanisms that could be therapeutic targets. To facilitate mechanistic studies, we adapted an inhibitory avoidance-based "2-hit" rat model of posttraumatic stress dis