Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michael Q Jiang"'
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-29 (2023)
Abstract Stroke and late-onset Alzheimer’s disease (AD) are risk factors for each other; the comorbidity of these brain disorders in aging individuals represents a significant challenge in basic research and clinical practice. The similarities and
Externí odkaz:
https://doaj.org/article/e1512064a32a46c7a8810611d864651b
Autor:
Michael Q. Jiang, Shan Ping Yu, Takira Estaba, Emily Choi, Ken Berglund, Xiaohuan Gu, Ling Wei
Publikováno v:
Cells, Vol 13, Iss 11, p 897 (2024)
Glioblastoma Multiforme (GBM) is an aggressive brain tumor with a high mortality rate. Direct reprogramming of glial cells to different cell lineages, such as induced neural stem cells (iNSCs) and induced neurons (iNeurons), provides genetic tools to
Externí odkaz:
https://doaj.org/article/d9f96a52e6a14a819bd34e608ad3d040
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 7, Pp 1981-1988 (2025)
Stroke and Alzheimer’s disease are common neurological disorders and often occur in the same individuals. The comorbidity of the two neurological disorders represents a grave health threat to older populations. This review presents a brief backgrou
Externí odkaz:
https://doaj.org/article/251f1265aad8444da1f13bdbb1a09912
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c3e793f600889c40f3aeac12dae33c8
https://doi.org/10.1002/alz.067285
https://doi.org/10.1002/alz.067285
Autor:
Christina Gross, Chia-Wei Chang, Seth M. Kelly, Aditi Bhattacharya, Sean M.J. McBride, Scott W. Danielson, Michael Q. Jiang, Chi Bun Chan, Keqiang Ye, Jay R. Gibson, Eric Klann, Thomas A. Jongens, Kenneth H. Moberg, Kimberly M. Huber, Gary J. Bassell
Publikováno v:
Cell Reports, Vol 11, Iss 5, Pp 727-736 (2015)
The PI3K enhancer PIKE links PI3K catalytic subunits to group 1 metabotropic glutamate receptors (mGlu1/5) and activates PI3K signaling. The roles of PIKE in synaptic plasticity and the etiology of mental disorders are unknown. Here, we show that inc
Externí odkaz:
https://doaj.org/article/6d5a60cc40a74af292e9a546286e3426
Autor:
Myles R. McCrary, Michael Q. Jiang, Kaleena Jesson, Xiaohuan Gu, Meghan T. Logun, Anika Wu, Nathan Gonsalves, Lohitash Karumbaiah, Shan Ping Yu, Ling Wei
Publikováno v:
Exp Neurol
Ischemic stroke is a leading cause of morbidity and mortality, with limited treatments that can facilitate brain regeneration. Neural progenitor cells (NPCs) hold promise for replacing tissue lost to stroke, and biomaterial approaches may improve the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa210e0bf3f4113c41c763c771c1240
https://doi.org/10.1016/j.expneurol.2022.114177
https://doi.org/10.1016/j.expneurol.2022.114177
Autor:
Michael Q. Jiang, Shan P. Yu, Huang Xin, Xiaohuan Gu, Michelle M. Giddens, Myles R. McCrary, Ling Wei, Weiwei Zhong, James Zhang, Randy A. Hall, Sharon Owino, Zheng Zachory Wei
Publikováno v:
FASEB J
GPCR 37 (GPR37) is a GPCR expressed in the CNS; its physiological and pathophysiological functions are largely unknown. We tested the role of GPR37 in the ischemic brain of GPR37 knockout (KO) mice, exploring the idea that GPR37 might be protective a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f3e2a6ae098a1f2b01bcf9d572a08e
https://europepmc.org/articles/PMC6766648/
https://europepmc.org/articles/PMC6766648/
Autor:
Michael Q. Jiang, Ling Wei, Stephen Tan, Lohitash Karumbaiah, Zheng Zachory Wei, Christopher Lenear, Meghan T. Logun, Shan Ping Yu, Myles R. McCrary, Xiaohuan Gu, Kaleena Jesson
Publikováno v:
Adv Healthc Mater
Stroke causes significant mortality and morbidity. Currently, there are no treatments which can regenerate brain tissue lost to infarction. Neural progenitor cells (NPCs) are at the forefront of preclinical studies for regenerative stroke therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5430f08eebb35f2e6a24ee7e51b18089
https://doi.org/10.1002/adhm.201900285
https://doi.org/10.1002/adhm.201900285
Autor:
Chia Wei Chang, Thomas A. Jongens, Sean M.J. McBride, Keqiang Ye, Aditi Bhattacharya, Kenneth H. Moberg, Eric Klann, Chi Bun Chan, Michael Q. Jiang, Gary J. Bassell, Scott Walter Danielson, Jay R. Gibson, Kimberly M. Huber, Christina Gross, Seth M. Kelly
Publikováno v:
Cell Reports, Vol 11, Iss 5, Pp 727-736 (2015)
SummaryThe PI3K enhancer PIKE links PI3K catalytic subunits to group 1 metabotropic glutamate receptors (mGlu1/5) and activates PI3K signaling. The roles of PIKE in synaptic plasticity and the etiology of mental disorders are unknown. Here, we show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d150fe429bc3c9fb017c2b6ffde0b8
http://www.sciencedirect.com/science/article/pii/S2211124715003514
http://www.sciencedirect.com/science/article/pii/S2211124715003514