Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michael Pudjihartono"'
Autor:
Michael Pudjihartono, Evgeniia Golovina, Tayaza Fadason, Justin M. O'Sullivan, William Schierding
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 1031-1048 (2024)
Genome‐wide association studies (GWAS) have associated 76 loci with the risk of developing melanoma. However, understanding the molecular basis of such associations has remained a challenge because most of these loci are in non‐coding regions of
Externí odkaz:
https://doaj.org/article/cbc11b2d72d64248b311024e1ffd34e5
Autor:
Sophie L. Farrow, Sreemol Gokuladhas, William Schierding, Michael Pudjihartono, Jo K. Perry, Antony A. Cooper, Justin M. O’Sullivan
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Genome wide association studies (GWAS) have identified a number of genomic loci that are associated with Parkinson’s disease (PD) risk. However, the majority of these variants lie in non-coding regions, and thus the mechanisms by which the
Externí odkaz:
https://doaj.org/article/777c62e53bcb4a74b6e99d11f4201189
Autor:
Sam A Jamieson, Michael Pudjihartono, Christopher R Horne, Robert C Day, James M Murphy, Peter D Mace
Tribbles proteins (TRIB1–3) are a pseudokinase-only branch of the human kinome, which recruit substrates to the COP1 ubiquitin-ligase for ubiquitination. TRIB2 was the first Tribbles ortholog to be implicated as a myeloid leukaemia oncogene, by way
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2aa533ade6b5cce602d64c5dfdd99bd
https://doi.org/10.1101/2022.04.29.489987
https://doi.org/10.1101/2022.04.29.489987
Autor:
Sam A. Jamieson, Michael Pudjihartono, Christopher R. Horne, Juan Salamanca Viloria, Jessica L. Dunlop, Hamish D. McMillan, Robert C. Day, Karen Keeshan, James M. Murphy, Peter D. Mace
Publikováno v:
Structure (London, England : 1993). 30(11)
Tribbles proteins (TRIB1-3) are pseudokinases that recruit substrates to the COP1 ubiquitin ligase. TRIB2 was the first Tribbles ortholog to be implicated as a myeloid leukemia oncogene, because it recruits the C/EBPα transcription factor for ubiqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e69107dc5d7d61022cfb0a2aea52fb3
https://pubmed.ncbi.nlm.nih.gov/36332608
https://pubmed.ncbi.nlm.nih.gov/36332608
Publikováno v:
Clinical epigenetics. 14(1)
Background There has been extensive scrutiny of cancer driving mutations within the exome (especially amino acid altering mutations) as these are more likely to have a clear impact on protein functions, and thus on cell biology. However, this has com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e2c4e70e25d5129f37d2b9587bcfaf
https://pubmed.ncbi.nlm.nih.gov/36171609
https://pubmed.ncbi.nlm.nih.gov/36171609