Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Michael Preukschas"'
Autor:
Henning Sievert, Nora Pällmann, Katharine K. Miller, Irm Hermans-Borgmeyer, Simone Venz, Ataman Sendoel, Michael Preukschas, Michaela Schweizer, Steffen Boettcher, P. Christoph Janiesch, Thomas Streichert, Reinhard Walther, Michael O. Hengartner, Markus G. Manz, Tim H. Brümmendorf, Carsten Bokemeyer, Melanie Braig, Joachim Hauber, Kent E. Duncan, Stefan Balabanov
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 8, Pp 963-976 (2014)
The central importance of translational control by post-translational modification has spurred major interest in regulatory pathways that control translation. One such pathway uniquely adds hypusine to eukaryotic initiation factor 5A (eIF5A), and the
Externí odkaz:
https://doaj.org/article/1c3ec82d54394b81a23dc5254fab1567
Autor:
Michael Preukschas, Christian Hagel, Alexander Schulte, Kristoffer Weber, Katrin Lamszus, Henning Sievert, Nora Pällmann, Carsten Bokemeyer, Joachim Hauber, Melanie Braig, Stefan Balabanov
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43468 (2012)
Glioblastomas are highly aggressive brain tumors of adults with poor clinical outcome. Despite a broad range of new and more specific treatment strategies, therapy of glioblastomas remains challenging and tumors relapse in all cases. Recent work demo
Externí odkaz:
https://doaj.org/article/be8aa09ce7fd49a9bb62600e7a6decc7
Publikováno v:
Leukemia research. 76
Gene expression profiling (GEP) separated diffuse large B-cell lymphoma (DLBCL) in two different entities, i.e. activated B cell-like (ABC) and germinal center B cell-like (GCB) lymphomas with ABC lymphomas demonstrating a less favorable outcome. NF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4f52a273f08f0cb9749b5b1411b99b
https://pubmed.ncbi.nlm.nih.gov/30473330
https://pubmed.ncbi.nlm.nih.gov/30473330
Autor:
Melanie Neumann, Henning Sievert, Claus-Henning Nagel, Michael Preukschas, Michaela Schweizer, Stefan Balabanov, Christian Hagel, Eugenia Haralambieva, Irm Hermans-Borgmeyer, Carsten Bokemeyer, Nora Pällmann, Peter J. Wild, Melanie Braig, Joachim Hauber
Publikováno v:
Journal of Biological Chemistry. 290:18343-18360
Hypusine modification of the eukaryotic initiation factor 5A (eIF-5A) is emerging as a crucial regulator in cancer, infections, and inflammation. Although its contribution in translational regulation of proline repeat-rich proteins has been sufficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fda458582d82310426d2e405348c78e
https://doi.org/10.1074/jbc.m115.664490
https://doi.org/10.1074/jbc.m115.664490
Autor:
Irm Hermans-Borgmeyer, P. Christoph Janiesch, Nora Pällmann, Kent E. Duncan, Henning Sievert, Simone Venz, Michael O. Hengartner, Stefan Balabanov, Thomas Streichert, Tim H. Brümmendorf, Markus G. Manz, Michaela Schweizer, Katharine K. Miller, Reinhard Walther, Ataman Sendoel, Michael Preukschas, Melanie Braig, Joachim Hauber, Steffen Boettcher, Carsten Bokemeyer
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 8, Pp 963-976 (2014)
Disease Models & Mechanisms
Disease models & mechanisms
Disease Models & Mechanisms
Disease models & mechanisms
The central importance of translational control by posttranslational modification has spurred major interest in regulatory pathways that control translation. One such pathway uniquely adds hypusine to eukaryotic initiation factor 5A (eIF5A), and ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5058b5cf4bca8c9728e10b24e44eb9
http://dmm.biologists.org/content/7/8/963
http://dmm.biologists.org/content/7/8/963
Autor:
Reinhard Walther, Kent E. Duncan, Joachim Hauber, Martin Schaletzky, Ralf Pörtner, Oscar Platas-Barradas, Stefan Balabanov, Melanie Braig, Claus-Henning Nagel, Carsten Bokemeyer, Vishnu M. Dhople, Simone Venz, Nora Pällmann, Henning Sievert, Tim H. Brümmendorf, Michael Preukschas
Publikováno v:
Molecular & cellular proteomics : MCP 11 (11): 1289-1305 (2012)
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Hypusine modification of eukaryotic initiation factor 5A (eIF-5A) represents a unique and highly specific post-translational modification with regulatory functions in cancer, diabetes, and infectious diseases. However, the specific cellular pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ae31ebc0a28b58a5fe895f18192889
https://doi.org/10.1074/mcp.m112.019059
https://doi.org/10.1074/mcp.m112.019059
Autor:
Tim H. Brümmendorf, Doris Steinemann, Mhairi Copland, Till Braunschweig, Karl Lenhard Rudolph, Michael Preukschas, Anne Gompf, Carsten Bokemeyer, Winfried Hofmann, Nora Pällmann, T Streichert, Stefan Balabanov, Melanie Braig, Andreas Schuppert, Steffen Koschmieder
Telomere biology is frequently associated with disease evolution in human cancer and dysfunctional telomeres have been demonstrated to contribute to genetic instability. In BCR-ABL(+) chronic myeloid leukemia (CML), accelerated telomere shortening ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5b0f96e443095863347eca0987c481
https://www.zora.uzh.ch/id/eprint/104785/
https://www.zora.uzh.ch/id/eprint/104785/
Autor:
Sergey N. Fedorov, Poornima Priyadarshini, Simone Venz, Stefan Balabanov, Reinhard Walther, Henning Sievert, Ina Naeth, Marcel Krepstakies, Christian Scharf, Larisa K. Shubina, Friedemann Honecker, Christine Jacobsen, Manuela Gesell Salazar, Michael Preukschas, Valentin A. Stonik, Carsten Bokemeyer, Joachim Hauber, Sergey A. Dyshlovoy
Publikováno v:
Journal of proteome research. 11(4)
Aaptamine is a marine compound isolated from the sponge Aaptos aaptos showing antiproliferative properties via an undefined mode of action. We analyzed the effects of aaptamine treatment on the proliferation and protein expression of the pluripotent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fb0919b94c637a5aab63d80841312a
https://pubmed.ncbi.nlm.nih.gov/22409352
https://pubmed.ncbi.nlm.nih.gov/22409352
Autor:
Carsten Bokemeyer, Christian Hagel, Melanie Braig, Stefan Balabanov, Kristoffer Weber, Alexander Schulte, Joachim Hauber, Nora Pällmann, Henning Sievert, Katrin Lamszus, Michael Preukschas
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43468 (2012)
PLoS ONE
PLoS ONE
Glioblastomas are highly aggressive brain tumors of adults with poor clinical outcome. Despite a broad range of new and more specific treatment strategies, therapy of glioblastomas remains challenging and tumors relapse in all cases. Recent work demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5440d9d398dd4bb8c7a6a0bd094af742
http://europepmc.org/articles/PMC3424167?pdf=render
http://europepmc.org/articles/PMC3424167?pdf=render
Autor:
Michael Preukschas, Andreas Schuppert, Stefan Balabanov, Winfried Hofmann, Nora Pällmann, Karl Lenhard Rudolph, Anne Gompf, Steffen Koschmieder, Carsten Bokemeyer, Melanie Braig, Doris Steinemann, Tim H. Brümmendorf
Publikováno v:
Blood. 122:3976-3976
Chronic myeloid leukemia (CML) is a hematopoietic stem cell (HSC) disease caused by the reciprocal translocation t(9;22). Although there is clear evidence that the resulting oncogenic tyrosine kinase BCR-ABL is the key event of leukemia initiation wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::244266118528778069f3467b45ead28d
https://doi.org/10.1182/blood.v122.21.3976.3976
https://doi.org/10.1182/blood.v122.21.3976.3976