Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michael Poglitsch"'
Autor:
Julia Ring, Jelena Tadic, Selena Ristic, Michael Poglitsch, Martina Bergmann, Nemanja Radic, Dirk Mossmann, YongTian Liang, Marta Maglione, Andrea Jerkovic, Roozbeh Hajiraissi, Marcel Hanke, Victoria Küttner, Heimo Wolinski, Andreas Zimmermann, Lana Domuz Trifunović, Leonie Mikolasch, Daiana N Moretti, Filomena Broeskamp, Julia Westermayer, Claudia Abraham, Simon Schauer, Christopher Dammbrueck, Sebastian J Hofer, Mahmoud Abdellatif, Guido Grundmeier, Guido Kroemer, Ralf J Braun, Niklas Hansen, Cornelia Sommer, Mirjana Ninkovic, Sandra Seba, Patrick Rockenfeller, Friederike‐Nora Vögtle, Jörn Dengjel, Chris Meisinger, Adrian Keller, Stephan J Sigrist, Tobias Eisenberg, Frank Madeo
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 5, Pp 1-26 (2022)
Abstract Amyloid beta 42 (Abeta42) is the principal trigger of neurodegeneration during Alzheimer’s disease (AD). However, the etiology of its noxious cellular effects remains elusive. In a combinatory genetic and proteomic approach using a yeast m
Externí odkaz:
https://doaj.org/article/4c65d2eea54842d29ae6240b593bf7ff
Autor:
Sabrina Schroeder, Sebastian J. Hofer, Andreas Zimmermann, Raimund Pechlaner, Christopher Dammbrueck, Tobias Pendl, G. Mark Marcello, Viktoria Pogatschnigg, Martina Bergmann, Melanie Müller, Verena Gschiel, Selena Ristic, Jelena Tadic, Keiko Iwata, Gesa Richter, Aitak Farzi, Muammer Üçal, Ute Schäfer, Michael Poglitsch, Philipp Royer, Ronald Mekis, Marlene Agreiter, Regine C. Tölle, Péter Sótonyi, Johann Willeit, Barbara Mairhofer, Helga Niederkofler, Irmgard Pallhuber, Gregorio Rungger, Herbert Tilg, Michaela Defrancesco, Josef Marksteiner, Frank Sinner, Christoph Magnes, Thomas R. Pieber, Peter Holzer, Guido Kroemer, Didac Carmona-Gutierrez, Luca Scorrano, Jörn Dengjel, Tobias Madl, Simon Sedej, Stephan J. Sigrist, Bence Rácz, Stefan Kiechl, Tobias Eisenberg, Frank Madeo
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108985- (2021)
Summary: Decreased cognitive performance is a hallmark of brain aging, but the underlying mechanisms and potential therapeutic avenues remain poorly understood. Recent studies have revealed health-protective and lifespan-extending effects of dietary
Externí odkaz:
https://doaj.org/article/39e2c2e4dbb64f9d873d1cd5180f9ef8
Autor:
Julia Ring, Patrick Rockenfeller, Claudia Abraham, Jelena Tadic, Michael Poglitsch, Katherina Schimmel, Julia Westermayer, Simon Schauer, Bettina Achleitner, Christa Schimpel, Barbara Moitzi, Gerald N. Rechberger, Stephan J. Sigrist, Didac Carmona-Gutierrez, Guido Kroemer, Sabrina Büttner, Tobias Eisenberg, Frank Madeo
Publikováno v:
Microbial Cell, Vol 4, Iss 12, Pp 411-422 (2017)
Hereditary spastic paraplegias, a group of neurodegenerative disorders, can be caused by loss-of-function mutations in the protein spartin. However, the physiological role of spartin remains largely elusive. Here we show that heterologous expression
Externí odkaz:
https://doaj.org/article/345f31f335df4374b65be0f350fe5c1c
Autor:
Sebastian Hofer, Katharina Kainz, Andreas Zimmermann, Maria A. Bauer, Tobias Pendl, Michael Poglitsch, Frank Madeo, Didac Carmona-Gutierrez
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Huntington’s disease (HD) is a neurodegenerative disorder that leads to progressive neuronal loss, provoking impaired motor control, cognitive decline, and dementia. So far, HD remains incurable, and available drugs are effective only for symptomat
Externí odkaz:
https://doaj.org/article/0cb749710aee4ff683f0fd3fc0641c54
Autor:
Claudia Abraham, Bettina Achleitner, Julia Westermayer, Gerald N. Rechberger, Jelena Tadic, Barbara Moitzi, Stephan J. Sigrist, Tobias Eisenberg, Christa Schimpel, Sabrina Büttner, Simon Schauer, Didac Carmona-Gutierrez, Katherina Schimmel, Frank Madeo, Patrick Rockenfeller, Michael Poglitsch, Julia Ring, Guido Kroemer
Publikováno v:
Microbial Cell
Microbial Cell, Vol 4, Iss 12, Pp 411-422 (2017)
Microbial Cell, Vol 4, Iss 12, Pp 411-422 (2017)
Hereditary spastic paraplegias, a group of neurodegenerative disorders, can be caused by loss-of-function mutations in the protein spartin. However, the physiological role of spartin remains largely elusive. Here we show that heterologous expression
Autor:
SreeDivya Saladi, Michael Poglitsch, Michael Schroda, Johannes M. Herrmann, Felix Boos, Maya Schuldiner, Frederik Sommer, Frank Madeo, Timo Mühlhaus, Hadar Meyer
Publikováno v:
Molecular cell. 77(1)
Summary The proteolytic turnover of mitochondrial proteins is poorly understood. Here, we used a combination of dynamic isotope labeling and mass spectrometry to gain a global overview of mitochondrial protein turnover in yeast cells. Intriguingly, w
Autor:
Timo Mühlhaus, Frank Madeo, SreeDivya Saladi, Johannes M. Herrmann, Frederik Sommer, Michael Schroda, Felix Boos, Michael Poglitsch
Publikováno v:
SSRN Electronic Journal.
Little is known about the proteolytic turnover of mitochondrial proteins under static growth conditions. Combining dynamic isotope labeling and mass spectrometry in yeast cells, we found an exceptionally high turnover for the NADH dehydrogenase Nde1.