Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Michael Perrais"'
Autor:
Romain Larrue, Sandy Fellah, Nihad Boukrout, Corentin De Sousa, Julie Lemaire, Carolane Leboeuf, Marine Goujon, Michael Perrais, Bernard Mari, Christelle Cauffiez, Nicolas Pottier, Cynthia Van der Hauwaert
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-10 (2023)
Abstract Non-small cell lung cancer is characterized by a dismal prognosis largely owing to inefficient diagnosis and tenacious drug resistance. Therefore, the identification of new molecular determinants underlying sensitivity of cancer cells to exi
Externí odkaz:
https://doaj.org/article/d531e7e391914dda9f2a07ce4706e812
Autor:
Edmone Dewaeles, Kévin Carvalho, Sandy Fellah, Jaewon Sim, Nihad Boukrout, Raphaelle Caillierez, Hariharan Ramakrishnan, Cynthia Van der Hauwaert, Jhenkruthi Vijaya Shankara, Nathalie Martin, Noura Massri, Agathe Launay, Joseph K. Folger, Clémentine de Schutter, Romain Larrue, Ingrid Loison, Marine Goujon, Matthieu Jung, Stéphanie Le Gras, Victoria Gomez-Murcia, Emilie Faivre, Julie Lemaire, Anne Garat, Nicolas Beauval, Patrice Maboudou, Viviane Gnemmi, Jean-Baptiste Gibier, Luc Buée, Corinne Abbadie, Francois Glowacki, Nicolas Pottier, Michael Perrais, Rodrigo A. Cunha, Jean-Sébastien Annicotte, Geoffroy Laumet, David Blum, Christelle Cauffiez
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
Cisplatin is a potent chemotherapeutic drug that is widely used in the treatment of various solid cancers. However, its clinical effectiveness is strongly limited by frequent severe adverse effects, in particular nephrotoxicity and chemotherapy-induc
Externí odkaz:
https://doaj.org/article/f322febb20a9426fac11bb1c684e29af
Autor:
Christian Lacks Lino Cardenas, Imène Sarah Henaoui, Elisabeth Courcot, Christoph Roderburg, Christelle Cauffiez, Sébastien Aubert, Marie-Christine Copin, Benoit Wallaert, François Glowacki, Edmone Dewaeles, Jadranka Milosevic, Julien Maurizio, John Tedrow, Brice Marcet, Jean-Marc Lo-Guidice, Naftali Kaminski, Pascal Barbry, Tom Luedde, Michael Perrais, Bernard Mari, Nicolas Pottier
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003291 (2013)
As miRNAs are associated with normal cellular processes, deregulation of miRNAs is thought to play a causative role in many complex diseases. Nevertheless, the precise contribution of miRNAs in fibrotic lung diseases, especially the idiopathic form (
Externí odkaz:
https://doaj.org/article/3b350d17f2374efab178def6a83ac45b
Autor:
David Bernard, Gérard Lambeau, Hélène Simonnet, Michael Gelb, Michael Perrais, Sébastien Aubert, Alain Puisieux, Xavier Leroy, Yvan de Launoit, Stéphanie Verbeke, Mylène Ferrand, Baptiste Gras, Benjamin Le Calvé, Clotilde Wiel, Helene Lallet-Daher, Delphine Gitenay, Christophe A. Girard, Arnaud Augert, David Vindrieux
PDF file - 326K, Supplementary Figure 1: The knockdown of PLA2R1 favors OIS escape. Supplementary Figure 2: The knockdown of PLA2R1 favors transformation. Supplementary Figure 3: The knockdown of PLA2R1 favors OIS escape in human normal keratinocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1d6f7ea4a0232b422887e273f56468
https://doi.org/10.1158/0008-5472.22396190
https://doi.org/10.1158/0008-5472.22396190
Autor:
E. Dewaeles, Grégoire Savary, Nicolas Pottier, J M Lo Guidice, C. Van Der Hauwaert, J Lemaire, Michael Perrais, François Glowacki, Christelle Cauffiez
Publikováno v:
International Journal of Toxicology
International Journal of Toxicology, 2020, International Journal of Toxicology, 39 (2), pp.103-114. ⟨10.1177/1091581819899039⟩
International Journal of Toxicology, 2020, International Journal of Toxicology, 39 (2), pp.103-114. ⟨10.1177/1091581819899039⟩
International audience; Cadmium is an environmental pollutant well known for its nephrotoxic effects. Nevertheless, mechanisms underlying nephrotoxicity continue to be elucidated. MicroRNAs (miRNAs) have emerged in recent years as modulators of xenob
Autor:
Jean-Baptiste Gibier, Isabelle Van Seuningen, Thomas Swierczewski, Patrice Maboudou, Nicolas Pottier, Sébastien Aubert, Brigitte Hémon, François Glowacki, Michael Perrais, Marie Csanyi, Christelle Cauffiez, Viviane Gnemmi
Publikováno v:
Shock
Shock, Lippincott, Williams & Wilkins, 2021, 56 (4), pp.629-638. ⟨10.1097/SHK.0000000000001742⟩
Shock, 2021, 56 (4), pp.629-638. ⟨10.1097/SHK.0000000000001742⟩
Shock, Lippincott, Williams & Wilkins, 2021, 56 (4), pp.629-638. ⟨10.1097/SHK.0000000000001742⟩
Shock, 2021, 56 (4), pp.629-638. ⟨10.1097/SHK.0000000000001742⟩
Sepsis is the leading cause of acute kidney injury (AKI) in critical care patients. A cornerstone of sepsis-associated AKI is dysregulated inflammation driven by excessive activation of Toll-like receptor 4 (TLR4) pathway. MUC1, a membrane bound muci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ea352c4f09d4ef04ce0daf5d4a9074
https://hal.archives-ouvertes.fr/hal-03379151
https://hal.archives-ouvertes.fr/hal-03379151
Publikováno v:
Bulletin du Cancer
Bulletin du Cancer, John Libbey Eurotext, 2020, 107, pp.1148-1160. ⟨10.1016/j.bulcan.2020.08.004⟩
Bulletin du Cancer, 2020, 107, pp.1148-1160. ⟨10.1016/j.bulcan.2020.08.004⟩
Bulletin du Cancer, John Libbey Eurotext, 2020, 107, pp.1148-1160. ⟨10.1016/j.bulcan.2020.08.004⟩
Bulletin du Cancer, 2020, 107, pp.1148-1160. ⟨10.1016/j.bulcan.2020.08.004⟩
International audience; La tumorigenèse a traditionnellement été considérée comme un processus en plusieurs étapes impliquant l’activation des oncogènes ainsi que l’inactivation des gènes suppresseurs de tumeurs. Cependant, les mécanisme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9999054b8e47d671fd627dd12606e28
https://hal.archives-ouvertes.fr/hal-03493799
https://hal.archives-ouvertes.fr/hal-03493799
Publikováno v:
Bulletin du cancer. 107(11)
Tumorigenesis has traditionally been considered as a multi-step process involving the activation of oncogenes as well as the inactivation of tumor suppressor genes. However, the mechanisms driving cancer initiation and progression are not restricted
Autor:
Nicolas Wayolle, Marie Frimat, Claude-Alain Maurage, François Glowacki, Philippe Vanhille, Jean-Baptiste Gibier, Jérôme Verine, Cyrille Vandenbussche, Sarah Humez, Nassima Ramdane, Carole Cordonnier, Thomas Quemeneur, Pierre-Yves Hatron, Laura Bitton, Evelyne Mac Namara, Pierre Bataille, David Buob, Raymond Azar, Marie-Christine Copin, Viviane Gnemmi, Rémi Lenain, Michael Perrais
Publikováno v:
Journal of nephrology. 33(4)
The aims of this study were to determine whether tubulointerstitial damage in the form of interstitial fibrosis/tubular atrophy and total interstitial inflammation predicted progression to end stage renal disease (ESRD) and/or renal relapse (RR) in p
Autor:
Nihal Martis, Virginie Magnone, Franck Broly, Bruno Crestani, Pascal Barbry, Nicolas Nottet, Elisabeth Courcot, Nicolas Pottier, Imène-Sarah Henaoui, Grégoire Savary, Nicolas Pons, Roger Rezzonico, Benoit Wallaert, Bernard Mari, Kevin Lebrigand, Agnès Paquet, Matthieu Buscot, Véronique Hofman, Michael Perrais, François Glowacki, Julien Fassy, Cynthia Van der Hauwaert, Paul Hofman, Charles-Hugo Marquette, Sylvie Leroy, Edmone Dewaeles, Georges Vassaux, Christian L. Lino Cardenas, Andreas Günther, Christelle Cauffiez, Saverio Bellusci, Serena Diazzi, Julie Lemaire, Thierry Brousseau, Laurent Plantier
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2019, 200 (2), pp.184-198. ⟨10.1164/rccm.201807-1237OC⟩
American Journal of Respiratory and Critical Care Medicine, 2019, 200 (2), pp.184-198. ⟨10.1164/rccm.201807-1237OC⟩
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2019, 200 (2), pp.184-198. ⟨10.1164/rccm.201807-1237OC⟩
American Journal of Respiratory and Critical Care Medicine, 2019, 200 (2), pp.184-198. ⟨10.1164/rccm.201807-1237OC⟩
Rationale: Given the paucity of effective treatments for idiopathic pulmonary fibrosis (IPF), new insights into the deleterious mechanisms controlling lung fibroblast activation, the key cell type driving the fibrogenic process, are essential to deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e424679e109516d44a94df00182b5745
https://hal.archives-ouvertes.fr/hal-02413473
https://hal.archives-ouvertes.fr/hal-02413473