Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Michael Paskind"'
1
Structure and promoter activity of the mouse CDC25A gene
Autor: Jeffrey Voss, Diane Magada, Jennifer Timm, Michael Paskind, Paul M. Epstein, Dineli Wickramasinghe, Cynthia Johnston, Eilene Belanger, Laura Rodman
Publikováno v: Mammalian Genome. 11:1063-1069
CDC25A is a member of a group of highly related, dual-specificity phosphatases that promote cell cycle phase transitions by regulating the activity of cyclin-dependent kinases. Here we report the cloning and genomic sequence of 21,067 nucleotides enc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9854b363c7600c05b286fee24b163238
https://doi.org/10.1007/s003350010199
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2
Biochemical and functional analysis of mice deficient in expression of the CD45-associated phosphoprotein LPAP
Autor: Denis R. Alexander, Ping Li, Tara Seshadri, Diane Magada, Eddy Bruyns, Laura Rodman, Thomas Giese, Burkhart Schraven, Michael Paskind, Isabelle Ding
Publikováno v: European Journal of Immunology. 29:3956-3961
The role of the CD45-associated phosphoprotein (LPAP / CD45-AP) during an immune response remains unclear. To understand better the function of LPAP we generated LPAP-deficient mice by disrupting exon 2 of the LPAP gene. LPAP-null mice were healthy a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37ca571eb40945a8c6d36ea4726c5d2
https://doi.org/10.1002/(sici)1521-4141(199912)29:12<3956::aid-immu3956>3.0.co
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3
Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock
Autor: Cynthia Johnston, Elizabeth Towne, Tara Seshadri, Michael Paskind, Robert Kamen, Feng-Yi Wei, Laura Rodman, Scott Wardwell, Hamish Allen, Winnie W. Wong, Daniel E. Tracey, Ping Li, Linda Herzog, Subhashis Banerjee, Jochen G. Salfeld, Jack McDowell, Simon Franklin
Publikováno v: Cell. 80(3):401-411
IL-1 beta-converting enzyme (ICE) cleaves pro-IL-1 beta to generate mature IL-1 beta. ICE is homologous to other proteins that have been implicated in apoptosis, including CED-3 and Nedd-2/lch-1. We generated ICE-deficient mice and observed that they
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb83fc5b0fe2f183a202b194e25aaa2
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4
Cladistic analyses of combined traditional and molecular data sets reveal an algal lineage
Autor: Robert A. Andersen, Daniel Potter, Michael Paskind, Gary W. Saunders
Publikováno v: Proceedings of the National Academy of Sciences. 92:244-248
The chromophyte algae are a large and biologically diverse assemblage of brown seaweeds, diatoms, and other golden algae classified in 13 taxonomic classes. One subgroup (diatoms, pedinellids, pelagophytes, silicoflagellates, and certain enigmatic ge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb23e3e54aeda1cdca80acbf2676643
https://doi.org/10.1073/pnas.92.1.244
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5
A Novel Cyclic GMP Stimulated Phosphodiesterase from Rat Brain
Autor: Michael Paskind, L. S. Cutler, G. Bolger, W. J. Thompson, Paul M. Epstein, D. R. Repaske, Qi Yang
Publikováno v: Biochemical and Biophysical Research Communications. 205:1850-1858
A cDNA clone for cyclic GMP Stimulated Phosphodiesterase (cGSPDE; PDE2) was isolated from a rat brain cDNA library. The cDNA has an open reading frame which encodes a protein of 928 amino acids of which 829 are identical with the reported bovine adre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369b223c6244464ecdce3fcd06141784
https://doi.org/10.1006/bbrc.1994.2886
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7
Expression and regulation of mRNA for distinct isoforms of cAMP-specific PDE-4 in mitogen-stimulated and leukemic human lymphocytes
Autor: Paul M. Epstein, Michael Paskind, Robert Bernard Weltzien, Xin Jiang
Publikováno v: Cell biochemistry and biophysics. 28(2-3)
We reported previously that the gene for PDE-1B1 is induced in isolated human peripheral blood lymphocytes (HPBL) following mitogenic stimulation (Jiang, X., Li, J., Paskind, M., and Epstein, P.M. [1996] Proc. Natl. Acad. Sci. USA 93, 11,236-11,241).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad2462b940ddc4d90d4c2a81f5be1d2
https://pubmed.ncbi.nlm.nih.gov/9515164
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8
Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases
Autor: Michael Paskind, Christoph W. Turck, Joanne Kamens, David G. Motto, M A Musci, L. Ranee Hendricks-Taylor, Gary A. Koretzky
Publikováno v: The Journal of biological chemistry. 272(18)
Previous work has demonstrated that SLP-76, a Grb2-associated tyrosine-phosphorylated protein, augments Interleukin-2 promoter activity when overexpressed in the Jurkat T cell line. This activity requires regions of SLP-76 that mediate protein-protei
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a315ddacf29340230a3e2ba7966ca2
https://pubmed.ncbi.nlm.nih.gov/9115214
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9
Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production
Autor: Margaret Hugunin, Robert V. Talanian, L. Sekut, H. Allen, A. Carter, Michael Paskind, T. Ghayur, Daniel E. Tracey, D. Butler, S. Banerjee, Winnie W. Wong, Linda Herzog, L. Quintal, Robert Kamen
Publikováno v: Nature. 386(6625)
Interferon-gamma-inducing factor (IGIF, interleukin-18) is a recently described cytokine that shares structural features with the interleukin-1 (IL-1) family of proteins and functional properties with IL-12. Like IL-12, IGIF is a potent inducer of in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423d0e5749342ab03b29ca7a1a62747f
https://pubmed.ncbi.nlm.nih.gov/9121587
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10
Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells
Autor: Paul M. Epstein, J Li, Michael Paskind, Xin Jiang
Cytosolic extracts from a human lymphoblastoid B-cell line, RPMI-8392, established from a patient with acute lymphocytic leukemia, contain two major forms of cyclic nucleotide phosphodiesterase (PDE): Ca2+-calmodulin dependent PDE (PDE1) and cAMP-spe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a616334ba1627427d9e0c774f2010e
https://europepmc.org/articles/PMC1074519/
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