Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Michael P. O'Hagan"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nucleic acid-based constitutional dynamic networks (CDNs) enable control of various catalytic processes, but it is challenging to achieve intercommunication between different CDNs and by that mimic complex cell biology networks. Here, the authors rep
Externí odkaz:
https://doaj.org/article/a56cf9908f5d44efb55712f5da647326
Autor:
Michael P. O’Hagan, Zhijuan Duan, Fujian Huang, Shay Laps, Jiantong Dong, Fan Xia, Itamar Willner
Publikováno v:
Chemical Reviews. 123:6839-6887
Publikováno v:
The Journal of Physical Chemistry B. 126:8931-8939
A method to computationally and experimentally identify aptamers against short peptides or amino acid clusters is introduced. The method involves the selection of a well-defined protein aptamer complex and the extraction of the peptide sequence parti
Publikováno v:
Advanced Materials.
Publikováno v:
ACS Nano. 16:6153-6164
The dynamic transient formation and depletion of G-quadruplexes regulate gene replication and transcription. This process was found to be related to various diseases such as cancer and premature aging. We report on the engineering of nucleic acid mod
Publikováno v:
ACS Nano. 16:3625-3636
Transient dissipative dimerization and transient gated dimerization of DNA tetrahedra nanostructures are introduced as functional modules to emulate transient and gated protein-protein interactions and emergent protein-protein guided transient cataly
Publikováno v:
Chemical Society Reviews. 51:720-760
Photoresponsive nucleic acids attract growing interest as functional constituents in materials science. Integration of photoisomerizable units into DNA strands provides an ideal handle for the reversible reconfiguration of nucleic acid architectures
An Azobenzene G-quadruplex Ligand Exhibits Promising Antibacterial Activity against Escherichia coli
Autor:
Javier Ramos-Soriano, Yuiko Takebayashi, Jenny Samphire, Michael P. O’Hagan, Catherine Gurr, Kate J. Heesom, Philip A. Lewis, James Spencer, M. Carmen Galan
With the rise in bacterial antimicrobial resistance (AMR) and decline in antibiotic discovery, global healthcare is at a point of jeopardy. There is great need for the development of novel antimicrobials that target bacteria that have become resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b402d4eff55808bd4ef1d73a2d383e8
https://doi.org/10.1101/2022.09.01.506212
https://doi.org/10.1101/2022.09.01.506212
Publikováno v:
Biosensorsbioelectronics. 218
Nanoparticles exhibiting diverse shapes, high porosity and chemical stability reveal, upon appropriate chemical engineering, enzyme-like catalytic activities, "nanozymes", providing a plethora of nanomaterials for diverse applications. The present re
Publikováno v:
Chemical Society reviews. 51(17)
G-Quadruplexes attract growing interest as functional constituents in biology, chemistry, nanotechnology, and material science. In particular, the reversible dynamic reconfiguration of G-quadruplexes provides versatile means to switch DNA nanostructu