Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Michael P. Murrell"'
Autor:
Ryota Sakamoto, Michael P. Murrell
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract The architecture of the actin cortex determines the generation and transmission of stresses, during key events from cell division to migration. However, its impact on myosin-induced cell shape changes remains unclear. Here, we reconstitute a
Externí odkaz:
https://doaj.org/article/6895be581b23473b82e924cb2b54b208
Autor:
Ryota Sakamoto, Michael P. Murrell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Mechanical work serves as the foundation for dynamic cellular processes, ranging from cell division to migration. A fundamental driver of cellular mechanical work is the actin cytoskeleton, composed of filamentous actin (F-actin) and myosin
Externí odkaz:
https://doaj.org/article/f254bf6fae8541f08530831134c03e7e
Autor:
Ryota Sakamoto, Deb Sankar Banerjee, Vikrant Yadav, Sheng Chen, Margaret L. Gardel, Cecile Sykes, Shiladitya Banerjee, Michael P. Murrell
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract The accumulation and transmission of mechanical stresses in the cell cortex and membrane determines the mechanics of cell shape and coordinates essential physical behaviors, from cell polarization to cell migration. However, the extent that
Externí odkaz:
https://doaj.org/article/9bd7e0eb77e84076a6a7829e5fc025aa
Autor:
Hao Xing, Yaqing Huang, Britta H. Kunkemoeller, Peter J. Dahl, Ohvia Muraleetharan, Nikhil S. Malvankar, Michael P. Murrell, Themis R. Kyriakides
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Fibroblasts are a major cell population that perform critical functions in the wound healing process. In response to injury, they proliferate and migrate into the wound space, engaging in extracellular matrix (ECM) production, remodeling, an
Externí odkaz:
https://doaj.org/article/35f522ea9461476c84e5977ad15c6359
Autor:
Camelia G. Muresan, Zachary Gao Sun, Vikrant Yadav, A. Pasha Tabatabai, Laura Lanier, June Hyung Kim, Taeyoon Kim, Michael P. Murrell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
While the impact of F-actin architecture on stress transmission is well studied, the role of architecture on stress generation remains unclear. Here authors use in vitro model and show that distinct organizations constrain myosin motion.
Externí odkaz:
https://doaj.org/article/6d55664092a14c27b843ceb4e3c4c667
Autor:
Ryota Sakamoto, Deb Sankar Banerjee, Vikrant Yadav, Sheng Chen, Margaret L. Gardel, Cecile Sykes, Shiladitya Banerjee, Michael P. Murrell
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/47a7376c3f404b90b89578f017f100b7
Autor:
Hao Xing, Yaqing Huang, Britta H. Kunkemoeller, Peter J. Dahl, Ohvia Muraleetharan, Nikhil S. Malvankar, Michael P. Murrell, Themis R. Kyriakides
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/f2456d6b09fe43fca37482eb0f2d8ea3
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The degree of irreversibility of a dynamical system is commonly characterized by the total rate of entropy production. Seara et al. introduce a measure that quantifies irreversibility from data in broad classes of spatiotemporal non-equilibrium syste
Externí odkaz:
https://doaj.org/article/781bff7543274c989359ff12c5fc974b
Autor:
Daniel S. Seara, Vikrant Yadav, Ian Linsmeier, A. Pasha Tabatabai, Patrick W. Oakes, S. M. Ali Tabei, Shiladitya Banerjee, Michael P. Murrell
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Myosin motors drive the actin cytoskeleton out-of-equilibrium, but the role of myosin-driven active stresses in the accumulation and dissipation of mechanical work is unclear. Here, the authors synthesize an actomyosin material and find that the rate
Externí odkaz:
https://doaj.org/article/e3e9d17bb7974171ac8d4a2c7e5a28d3
Autor:
Ian Linsmeier, Shiladitya Banerjee, Patrick W. Oakes, Wonyeong Jung, Taeyoon Kim, Michael P. Murrell
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
The interaction between myosin motors and F-actin is well described, but the impact of actin organization on contractility is not well described. Here the authors use a 2D biomimetic system and computational modelling to show that contractility of is
Externí odkaz:
https://doaj.org/article/b1543311161c4ab594e4d510e47bab9e