Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michael P. Lees"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Understanding how contact patterns arise from crowd movement is crucial for assessing the spread of infection at mass gathering events. Here we study contact patterns from Wi-Fi mobility data of large sports and entertainment events in the J
Externí odkaz:
https://doaj.org/article/a1f5a6e5aece427cb8a681c0434043b0
Autor:
Valentin R. Melnikov, Georgios I. Christopoulos, Valeria V. Krzhizhanovskaya, Michael H. Lees, Peter M. A. Sloot
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Due to phenomena such as urban heat islands, outdoor thermal comfort of the cities’ residents emerges as a growing concern. A major challenge for mega-cities in changing climate is the design of urban spaces that ensure and promote pedestr
Externí odkaz:
https://doaj.org/article/1362421ab620452d9e2a0e5a13e3ace4
Publikováno v:
EPJ Data Science, Vol 10, Iss 1, Pp 1-26 (2021)
Abstract Pedestrian movements during large crowded events naturally consist of different modes of movement behaviour. Despite its importance for understanding crowd dynamics, intermittent movement behaviour is an aspect missing in the existing crowd
Externí odkaz:
https://doaj.org/article/9123b4528a7a4e40af41ab4c00a3dbba
Autor:
Oksana Severiukhina, Sergey Kesarev, Klavdiya Bochenina, Alexander Boukhanovsky, Michael H. Lees, Peter M. A. Sloot
Publikováno v:
Journal of Big Data, Vol 7, Iss 1, Pp 1-17 (2020)
Abstract This research proposes a system based on a combination of various components for parallel modelling and forecasting the processes in networks with data assimilation from the real network. The main novelty of this work consists of the assimil
Externí odkaz:
https://doaj.org/article/95c13b7d0e3444799fa0c2396c7ee535
Autor:
Susanne Marije Kooistra, Lise Christine Rudkjær Nørgaard, Michael James Lees, Cornelia Steinhauer, Jens Vilstrup Johansen, Kristian Helin
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0272206 (2022)
[This corrects the article DOI: 10.1371/journal.pone.0091034.].
Externí odkaz:
https://doaj.org/article/9eac75daf56e476cad379522a9a8bb3c
Autor:
Petrus M.A. Sloot, Janusz Holyst, George Kampis, Michael Harold Lees, Sergey A. Mityagin, Sergey V. Ivanov, Klavdiya O. Bochenina, Valentina Yu. Guleva, Ksenia D. Mukhina, Denis A. Nasonov, Nikolay A. Butakov, Vasiliy N. Leonenko, Anastasia A. Lantseva
Publikováno v:
Naučno-tehničeskij Vestnik Informacionnyh Tehnologij, Mehaniki i Optiki, Vol 16, Iss 6, Pp 967-995 (2014)
The paper describes a problem of computer simulation of critical phenomena in complex social systems on a petascale computing systems in frames of complex networks approach. The three-layer system of nested models of complex networks is proposed incl
Externí odkaz:
https://doaj.org/article/f8df0caf82c743b68904ccea8e8973f8
Autor:
Susanne Marije Kooistra, Lise Christine Rudkjær Nørgaard, Michael James Lees, Cornelia Steinhauer, Jens Vilstrup Johansen, Kristian Helin
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91034 (2014)
Oncogene-induced senescence (OIS) can occur in response to hyperactive oncogenic signals and is believed to be a fail-safe mechanism protecting against tumorigenesis. To identify new factors involved in OIS, we performed a screen for microRNAs that c
Externí odkaz:
https://doaj.org/article/19b38e126b7646daadcd6a9127e78f5d
Autor:
Catherine M Miller, Nicola R Boulter, Stephen J Fuller, Alana M Zakrzewski, Michael P Lees, Bernadette M Saunders, James S Wiley, Nicholas C Smith
Publikováno v:
PLoS Pathogens, Vol 7, Iss 11, p e1002212 (2011)
ATP is an extracellular signal for the immune system, particularly during an inflammatory response. It is sensed by the P2X₇ receptor, the expression of which is upregulated by pro-inflammatory cytokines. Activation of the P2X₇ receptor opens a c
Externí odkaz:
https://doaj.org/article/eaae2f5f8dfd4171bed244a273cb96bf
Autor:
Nicholas Smith, Michael P. Lees, Stephen J. Fuller, Alana M. Zakrzewski, Nicola R. Boulter, James S. Wiley, Catherine M. Miller, Rowan J. Ikin, Marilyn Katrib
Publikováno v:
International Journal for Parasitology. 41:301-308
The P2X 7 receptor (P2X 7 R) is a two transmembrane receptor that is highly expressed on the surface of immune cells. Loss of function polymorphisms in this receptor have been linked to increased susceptibility to intracellular pathogens. P2X 7 R gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a730bb63d0b9d2906e4c2a53a779c7d9
https://doi.org/10.1016/j.ijpara.2010.10.001
https://doi.org/10.1016/j.ijpara.2010.10.001
Autor:
Ernest Mui, Rima McLeod, Jenefer M. Blackwell, Catherine M. Miller, Nicholas Smith, Alana M. Zakrzewski, Nicola R. Boulter, Sarra E. Jamieson, Stephen J. Fuller, James S. Wiley, Michael P. Lees, William H. Witola, Aubrey Hargrave, Jessica J. Coyne
Publikováno v:
The Journal of Immunology. 184:7040-7046
The P2X7R is highly expressed on the macrophage cell surface, and activation of infected cells by extracellular ATP has been shown to kill intracellular bacteria and parasites. Furthermore, single nucleotide polymorphisms that decrease receptor funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3730be8325dd599a2d277517cb4707c9
https://doi.org/10.4049/jimmunol.1000012
https://doi.org/10.4049/jimmunol.1000012