Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Michael P. King"'
Autor:
Abigail R. Fabiano, Spencer C. Robbins, Samantha V. Knoblauch, Schyler J. Rowland, Jenna A. Dombroski, Michael R. King
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Studying cellular mechanoresponses during cancer metastasis is limited by sample variation or complex protocols that current techniques require. Metastasis is governed by mechanotransduction, whereby cells translate external stimuli, such as
Externí odkaz:
https://doaj.org/article/10472b67d340482395246717360fa3f0
Autor:
Nicole S. Sarna, Shanay H. Desai, Benjamin G. Kaufman, Natalie M. Curry, Anne M. Hanna, Michael R. King
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109999- (2024)
Summary: The efficacy of T cell therapies in treating solid tumors is limited by poor in vivo persistence, proliferation, and cytotoxicity, which can be attributed to limited and variable ex vivo activation. Herein, we present a 10-day kinetic profil
Externí odkaz:
https://doaj.org/article/efd8f64110df41aa8dc6ed0f2c165f50
Autor:
Shankar Subramaniam, Metin Akay, Mark A. Anastasio, Vasudev Bailey, David Boas, Paolo Bonato, Ashutosh Chilkoti, Jennifer R. Cochran, Vicki Colvin, Tejal A. Desai, James S. Duncan, Frederick H. Epstein, Stephanie Fraley, Cecilia Giachelli, K. Jane Grande-Allen, Jordan Green, X. Edward Guo, Isaac B. Hilton, Jay D. Humphrey, Chris R Johnson, George Karniadakis, Michael R. King, Robert F. Kirsch, Sanjay Kumar, Cato T. Laurencin, Song Li, Richard L. Lieber, Nigel Lovell, Prashant Mali, Susan S. Margulies, David F. Meaney, Brenda Ogle, Bernhard Palsson, Nicholas A. Peppas, Eric J. Perreault, Rick Rabbitt, Lori A. Setton, Lonnie D. Shea, Sanjeev G. Shroff, Kirk Shung, Andreas S. Tolias, Marjolein C.H. van der Meulen, Shyni Varghese, Gordana Vunjak-Novakovic, John A. White, Raimond Winslow, Jianyi Zhang, Kun Zhang, Charles Zukoski, Michael I. Miller
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 5, Pp 1-13 (2024)
Over the past two decades Biomedical Engineering has emerged as a major discipline that bridges societal needs of human health care with the development of novel technologies. Every medical institution is now equipped at varying degrees of sophistica
Externí odkaz:
https://doaj.org/article/99aa19c8944b4368939a87375caa3abd
Autor:
Korie A. Grayson, Joshua D. Greenlee, Lauren E. Himmel, Lauren A. Hapach, Cynthia A. Reinhart-King, Michael R. King
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Mounting evidence suggests that the immune landscape within prostate tumors influences progression, metastasis, treatment response, and patient outcomes. In this study, we investigated the spatial density of innate immune cell populations within NOD.
Externí odkaz:
https://doaj.org/article/4c61c59810e74e768b62296fe8e62724
Autor:
Maria Lopez-Cavestany, Olivia A. Wright, Ava M. Cassidy, Alexandria T. Carter, Michael R. King
Publikováno v:
ACS Omega, Vol 8, Iss 45, Pp 42748-42761 (2023)
Externí odkaz:
https://doaj.org/article/eca2b3f4f5844498869f8fefcd4e1c1b
Autor:
Maria Lopez-Cavestany, Su Bin Hahn, Jacob M. Hope, Noah T. Reckhorn, Joshua D. Greenlee, Samantha C. Schwager, Jacob A. VanderBurgh, Cynthia A. Reinhart-King, Michael R. King
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106275- (2023)
Summary: Cells utilize calcium channels as one of the main signaling mechanisms to sense changes in the extracellular space and convert these changes to intracellular signals. Calcium regulates several key signaling networks, such as the induction of
Externí odkaz:
https://doaj.org/article/e150ebe4d8d04bd99f38fa0ec25e62ce
Autor:
Lindsay B. Young, Marcin Kolber, Michael J. King, Mona Ranade, Vivian L. Bishay, Rahul S. Patel, Francis S. Nowakowski, Aaron M. Fischman, Robert A. Lookstein, Edward Kim
Publikováno v:
Journal of Interventional Medicine, Vol 5, Iss 2, Pp 79-83 (2022)
Background: Hepatic tumors with complex vascular supply or poor relative perfusion are prone to decreased rates of objective response. This is compounded in the setting of Yttrium-90 (Y90) transarterial radioembolization (TARE), which is minimally em
Externí odkaz:
https://doaj.org/article/249018c45874475c94c700a0b2af130f
Autor:
Jacob M. Hope, Jenna A. Dombroski, Rebecca S. Pereles, Maria Lopez-Cavestany, Joshua D. Greenlee, Samantha C. Schwager, Cynthia A. Reinhart-King, Michael R. King
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background T cell activation is a mechanical process as much as it is a biochemical process. In this study, we used a cone-and-plate viscometer system to treat Jurkat and primary human T cells with fluid shear stress (FSS) to enhance the act
Externí odkaz:
https://doaj.org/article/393625c95a5b4e23af5124ff46e1efcc
Autor:
Jeffrey S. Thinschmidt, Scott W. Harden, Michael A. King, James D. Talton, Charles J. Frazier
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
We established a novel brain slice assay to test the ability of acetylcholinesterase (AChE) reactivators to prevent ACh-induced M1 muscarinic acetylcholine receptor (mAChR) dependent hyperexcitability observed after exposure to the organophosphate (O
Externí odkaz:
https://doaj.org/article/3545c7d60f87475388b0638bb2d7565a
Autor:
Jordan I. Gaelen, Michael R. King, John Hajduk, Angelica Vargas, David J. Krodel, Ravi D. Shah, Hubert A. Benzon
Publikováno v:
Children, Vol 10, Iss 8, p 1374 (2023)
Various regional anesthetics have been used for postoperative analgesia for pediatric craniotomy. In this case series, we report retrospectively collected data on postoperative pain and analgesic use in 44 patients who received ultrasound-guided occi
Externí odkaz:
https://doaj.org/article/8ac22811dce84713b4927d55c6e7a32f