Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Michael P. Kahle"'
Publikováno v:
Frontiers in Pharmacology, Vol 3 (2012)
The cerebral microvasculature is important for maintaining brain homeostasis. This is achieved via the blood-brain barrier (BBB), composed of endothelial cells with specialized tight junctions, astrocytes and a basement membrane. Prominent components
Externí odkaz:
https://doaj.org/article/0d1bead1fe3444bf86140a9c640e9051
Autor:
Michael P. Kahle, Gregory J. Bix
Publikováno v:
Stroke Research and Treatment, Vol 2012 (2012)
The Stroke Therapy Academic Industry Roundtable (STAIR) provided initial (in 1999) and updated (in 2009) recommendations with the goal of improving preclinical stroke therapy assessment and to increase the translational potential of experimental stro
Externí odkaz:
https://doaj.org/article/bfba87cb4bd045f59178102e1bcdfcb0
Autor:
Takeshi Shimamura, Julian Carretero, Kwok-Kin Wong, Pasi A. Jänne, Oscar Juan, Amelia Insa, Agustín Lahoz, Jeffrey A. Borgia, Fatima Al-Shahrour, Michael P. Kahle, Hajime Asahina, Ashley Hess, Patricia Simms, Camilla L. Christensen, Javier Alcácer, José M. Galbis-Caravajal, Antonio Cremades, Paloma Martín-Martorell, Javier Alcácer Fernández-Coronado, Miguel Aupí, Aranzazu Lafuente-Sanchis, Rutu Gandhi, María L. Rodríguez, Eiki Kikuchi, Ines Pulido, Margaret Soucheray, Yandi Gao, Jeffrey H. Becker
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f54a9e01b8e39179663f1e9a598dbc
https://doi.org/10.1158/0008-5472.22421373.v1
https://doi.org/10.1158/0008-5472.22421373.v1
Autor:
Takeshi Shimamura, Julian Carretero, Kwok-Kin Wong, Pasi A. Jänne, Oscar Juan, Amelia Insa, Agustín Lahoz, Jeffrey A. Borgia, Fatima Al-Shahrour, Michael P. Kahle, Hajime Asahina, Ashley Hess, Patricia Simms, Camilla L. Christensen, Javier Alcácer, José M. Galbis-Caravajal, Antonio Cremades, Paloma Martín-Martorell, Javier Alcácer Fernández-Coronado, Miguel Aupí, Aranzazu Lafuente-Sanchis, Rutu Gandhi, María L. Rodríguez, Eiki Kikuchi, Ines Pulido, Margaret Soucheray, Yandi Gao, Jeffrey H. Becker
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b60c5db3d8550b9937a2d7c74f5be54
https://doi.org/10.1158/0008-5472.22421370
https://doi.org/10.1158/0008-5472.22421370
Autor:
Takeshi Shimamura, Julian Carretero, Kwok-Kin Wong, Pasi A. Jänne, Oscar Juan, Amelia Insa, Agustín Lahoz, Jeffrey A. Borgia, Fatima Al-Shahrour, Michael P. Kahle, Hajime Asahina, Ashley Hess, Patricia Simms, Camilla L. Christensen, Javier Alcácer, José M. Galbis-Caravajal, Antonio Cremades, Paloma Martín-Martorell, Javier Alcácer Fernández-Coronado, Miguel Aupí, Aranzazu Lafuente-Sanchis, Rutu Gandhi, María L. Rodríguez, Eiki Kikuchi, Ines Pulido, Margaret Soucheray, Yandi Gao, Jeffrey H. Becker
Although EGFR mutant–selective tyrosine kinase inhibitors (TKI) are clinically effective, acquired resistance can occur by reactivating ERK. We show using in vitro models of acquired EGFR TKI resistance with a mesenchymal phenotype that CXCR7, an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a163c2049abde7c57bdfad3ee9c80405
https://doi.org/10.1158/0008-5472.c.6510909.v1
https://doi.org/10.1158/0008-5472.c.6510909.v1
Autor:
Takeshi Shimamura, Julian Carretero, Kwok-Kin Wong, Pasi A. Jänne, Oscar Juan, Amelia Insa, Agustín Lahoz, Jeffrey A. Borgia, Fatima Al-Shahrour, Michael P. Kahle, Hajime Asahina, Ashley Hess, Patricia Simms, Camilla L. Christensen, Javier Alcácer, José M. Galbis-Caravajal, Antonio Cremades, Paloma Martín-Martorell, Javier Alcácer Fernández-Coronado, Miguel Aupí, Aranzazu Lafuente-Sanchis, Rutu Gandhi, María L. Rodríguez, Eiki Kikuchi, Ines Pulido, Margaret Soucheray, Yandi Gao, Jeffrey H. Becker
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2542698ee5d6c4c7e9b3ca22cb3e6c3a
https://doi.org/10.1158/0008-5472.22421367
https://doi.org/10.1158/0008-5472.22421367
Autor:
Takeshi Shimamura, Julian Carretero, Kwok-Kin Wong, Pasi A. Jänne, Oscar Juan, Amelia Insa, Agustín Lahoz, Jeffrey A. Borgia, Fatima Al-Shahrour, Michael P. Kahle, Hajime Asahina, Ashley Hess, Patricia Simms, Camilla L. Christensen, Javier Alcácer, José M. Galbis-Caravajal, Antonio Cremades, Paloma Martín-Martorell, Javier Alcácer Fernández-Coronado, Miguel Aupí, Aranzazu Lafuente-Sanchis, Rutu Gandhi, María L. Rodríguez, Eiki Kikuchi, Ines Pulido, Margaret Soucheray, Yandi Gao, Jeffrey H. Becker
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dd10d9ca2ab853e14288d5829b67e1
https://doi.org/10.1158/0008-5472.22421364
https://doi.org/10.1158/0008-5472.22421364
Autor:
Amanda L Trout, Gregory J. Bix, Bret N. Smith, Stephen Grupke, Antonio Berretta, Andrew N. Clarkson, Ifechukwude Joachim Biose, Carie R. Boychuk, Aileen Marcelo, Jill Roberts, Danielle N. Edwards, Ibolya Rutkai, Michael P. Kahle, Amanda A. Gorman, Masafumi Ihara, Hatsue Ishibashi-Ueda, Emma K. Gowing, Jeffery A. Boychuk, Leon de Hoog
Publikováno v:
Translational Stroke Research
The extracellular matrix fragment perlecan domain V is neuroprotective and functionally restorative following experimental stroke. As neurogenesis is an important component of chronic post-stroke repair, and previous studies have implicated perlecan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43999c0374c37264151088c211a6d88
http://europepmc.org/articles/PMC7803718
http://europepmc.org/articles/PMC7803718
Autor:
Dong Yang, Yekaterina B. Khotskaya, Abu Shufean, Kenna R. Mills Shaw, Vijaykumar Holla, Michael P. Kahle, Amber Johnson, Funda Meric-Bernstam, Jia Zeng, Nora S. Sanchez, Elmer V. Bernstam
Publikováno v:
JCO Clinical Cancer Informatics. :1-11
PURPOSE Many targeted therapies are currently available only via clinical trials. Therefore, routine precision oncology using biomarker-based assignment to drug depends on matching patients to clinical trials. A comprehensive and up-to-date trial dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7592c03ee0a99ec0e43190d3e4aff873
https://doi.org/10.1200/cci.18.00145
https://doi.org/10.1200/cci.18.00145
Autor:
Ines Pulido, Javier Alcácer, Javier Alcácer Fernández-Coronado, Julian Carretero, José M. Galbis-Caravajal, Kwok-Kin Wong, Patricia E. Simms, Jeffrey H. Becker, Paloma Martín-Martorell, Rutu Gandhi, Margaret Soucheray, Miguel Aupi, Aránzazu Lafuente-Sanchis, Amelia Insa, Agustín Lahoz, Ashley Hess, Fatima Al-Shahrour, Camilla L. Christensen, Michael P. Kahle, Yandi Gao, Jeffrey A. Borgia, Oscar Juan, Maria L. Rodriguez, Hajime Asahina, Antonio Cremades, Eiki Kikuchi, Pasi A. Jänne, Takeshi Shimamura
Publikováno v:
CANCER RESEARCH
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Cancer research, vol 79, iss 17
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Cancer research, vol 79, iss 17
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
Although EGFR mutant–selective tyrosine kinase inhibitors (TKI) are clinically effective, acquired resistance can occur by reactivating ERK. We show using in vitro models of acquired EGFR TKI resistance with a mesenchymal phenotype that CXCR7, an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c52d2f5e680641900c05fb94312301
https://doi.org/10.1158/0008-5472.can-19-0024
https://doi.org/10.1158/0008-5472.can-19-0024