Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michael P. Housden"'
Autor:
Jeremy S. Parker, Michael P. Housden, Ian Paterson, Nelson Y. S. Lam, Jason S. Carroll, Stephen J. Walsh, David R. Spring, Talia R Pettigrew, Rachel J Porter
Publikováno v:
Chemical communications (Cambridge, England). 56(10)
The aplyronines are a family of highly cytotoxic marine natural products with potential application in targeted cancer chemotherapy. To address the severe supply issue, function-oriented molecular editing of their macrolactone scaffold led to the des
Publikováno v:
Organic & Biomolecular Chemistry. 16:1343-1350
The aplyronines are a family of antimitotic marine macrolides that disrupt cytoskeletal dynamics by dual targeting of both actin and tubulin. Given their picomolar cytotoxicity profile and unprecedented mode of action, the aplyronines represent an ex
Autor:
Michael P. Housden, N. C. Pyper
Publikováno v:
Molecular Physics. 105:2353-2361
The binding of the noble gas dimers is examined using a theory in which the Hartree–Fock interaction energy is augmented with both a short-range correlation term derived from the theory of a uniform electron-gas plus a dispersion energy damped acco
Autor:
Olivier Loiseleur, Michael P. Housden, Friedrich A. Mühlthau, Paul M. Burton, Ian Paterson, Christopher J. Cordier
The brasilinolides are an architecturally complex family of 32-membered macrolides, characterised by potent immunosuppressant and antifungal properties, which represent challenging synthetic targets. By adopting a highly convergent strategy, a range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7d04ded688452bcbb571f3f4817855
https://www.repository.cam.ac.uk/handle/1810/248111
https://www.repository.cam.ac.uk/handle/1810/248111
Autor:
Christopher J. Cordier, Michael P. Housden, Olivier Loiseleur, Paul M. Burton, Friedrich A. Mühlthau, Ian Paterson
Publikováno v:
Organic letters. 11(2)
Two highly convergent syntheses of a fully protected C1−C19 polyol subunit of the brasilinolide family of immunosuppressive macrolides are described, exploiting boron-mediated 1,5-anti aldol couplings to form the C8−C9 and C13−C14 bonds.
Autor:
Michael P. Housden, N C Pyper
Publikováno v:
Journal of Physics: Condensed Matter. 20:085222
A non-empirical fully ionic description, with the anion wavefunctions in their compressed but still spherically symmetrical states optimal for the crystal, is presented for the cohesive energetics of two cubic phases of three solid iodides, KI, RbI a
Autor:
Ian Paterson, Paul M. Burton, Christopher J. Cordier, Michael P. Housden, Friedrich A. Mühlthau, Olivier Loiseleur
Publikováno v:
Organic Letters; Feb2009, Vol. 11 Issue 3, p693-696, 4p
Autor:
Ian Paterson, Friedrich A. Mühlthau, Christopher J. Cordier, Michael P. Housden, Paul M. Burton, Olivier Loiseleur
Publikováno v:
Organic Letters; Jan2009, Vol. 11 Issue 2, p353-356, 4p