Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michael P. Gotsbacher"'
Publikováno v:
Proteome Science, Vol 15, Iss 1, Pp 1-15 (2017)
Abstract Background Daptomycin is a recently introduced, last-resort antibiotic that displays a unique mode of action against Gram-positive bacteria that is not fully understood. Several bacterial targets have been proposed but no human binding partn
Externí odkaz:
https://doaj.org/article/bc4ed3ef773f49f186bd6466d511555d
Autor:
Michael P. Gotsbacher, Peter Karuso
Publikováno v:
Marine Drugs, Vol 13, Iss 3, Pp 1389-1409 (2015)
Bioassay-guided fractionation of extracts from temperate Australian collections of the marine sponge Pseudoceratina purpurea resulted in the isolation and characterisation of two new and six known bromotyrosine-derived alkaloids with antibiotic activ
Externí odkaz:
https://doaj.org/article/546329b87b99470e88c772b57f9a9fcd
Autor:
Ivan Ho Shon, Thomas Hennessy, Jennifer Guille, Michael P. Gotsbacher, Angelina J. Lay, Bruce McBride, Rachel Codd, Philip J. Hogg
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:4037-4047
Purpose This study assesses human biodistribution, radiation dosimetry, safety and tumour uptake of cell death indicator labelled with 68Ga ([68Ga]Ga-CDI), a novel radiopharmaceutical that can image multiple forms of cell death. Methods Five particip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e8fe6921b5fbb402e1c6280b17a023
https://doi.org/10.1007/s00259-022-05880-z
https://doi.org/10.1007/s00259-022-05880-z
Autor:
Kate P. Nolan, Josep Font, Athavan Sresutharsan, Michael P. Gotsbacher, Christopher J. M. Brown, Renae M. Ryan, Rachel Codd
Publikováno v:
ACS Chemical Biology. 17:426-437
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0feb10f7117e5c58720977bfc0ea4dd9
https://doi.org/10.1021/acschembio.1c00879
https://doi.org/10.1021/acschembio.1c00879
Autor:
Michael P, Gotsbacher, Rachel, Codd
Publikováno v:
Methods in enzymology. 665
Converting discrete microbial metabolites into chemical probes for chemical biology and medicinal chemistry studies is typically preceded by lengthy purification and chemical derivatization processes. Standard practice involves purifying the target m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::359255040d2e067d254fe05317fd11c9
https://pubmed.ncbi.nlm.nih.gov/35379443
https://pubmed.ncbi.nlm.nih.gov/35379443
Autor:
Michael P. Gotsbacher, Rachel Codd
Publikováno v:
Methods in Enzymology ISBN: 9780323952675
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc7990a190d290ab2d245e4662b4879
https://doi.org/10.1016/bs.mie.2021.12.003
https://doi.org/10.1016/bs.mie.2021.12.003
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:2581-2586
Hydroxamic acid compounds 1-10 containing a N-hydroxycinnamamide scaffold and a 4-(benzylamino)methyl cap group that was either unsubstituted (1) or substituted with one (2-4) or two (5-10) methoxy groups in variable positions were prepared as inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c9f71b1e0bdf70f7d2db1a79514410
https://doi.org/10.1016/j.bmcl.2019.08.002
https://doi.org/10.1016/j.bmcl.2019.08.002
Publikováno v:
Australian Journal of Chemistry.
Two new linear tetrameric hydroxamic acid ligands (3 and 4) have been prepared as potential radioligands for immunological ZrIV-89 positron emission tomography (PET) imaging. The ligands were prepared by conjugating endo-hydroxamic acid amino carboxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d5e973481c3cee924f6c3f8e68a2a80
https://doi.org/10.1071/ch19518
https://doi.org/10.1071/ch19518
Publikováno v:
ACS Chemical Biology. 13:11-25
Desferrioxamine B (DFOB) was discovered in the late 1950s as a hydroxamic acid metabolite of the soil bacterium Streptomyces pilosus. The exquisite affinity of DFOB for Fe(III) identified its potential for removing excess iron from patients with tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3bc9b4bada0a38eeaaffd4d8634b57
https://doi.org/10.1021/acschembio.7b00851
https://doi.org/10.1021/acschembio.7b00851
Publikováno v:
Proteome Science, Vol 15, Iss 1, Pp 1-15 (2017)
Proteome Science
PROTEOME SCIENCE(15)
Proteome Science
PROTEOME SCIENCE(15)
Background Daptomycin is a recently introduced, last-resort antibiotic that displays a unique mode of action against Gram-positive bacteria that is not fully understood. Several bacterial targets have been proposed but no human binding partner is kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6dbee12c527a69aeac562b39c46483
http://link.springer.com/article/10.1186/s12953-017-0124-2
http://link.springer.com/article/10.1186/s12953-017-0124-2