Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Michael P. Goheen"'
Autor:
Zheng Dong, Shengmin Yan, Michael P. Goheen, Changshun Yu, Xiaoyun Chen, Yong Li, Shangwei Wu, Tiangang Li, Young-Min Lee, Gen-Sheng Feng, Scott L. Friedman, Jingmei Lin, Oscar W. Cummings, Xiao Ming Yin, Bilon Khambu
Publikováno v:
Hepatology
Autophagy is important for hepatic homeostasis, nutrient regeneration, and organelle quality control. We investigated the mechanisms by which liver injury occurred in the absence of autophagy function. We found that mice deficient in autophagy becaus
Publikováno v:
Modern Pathology. 24:1320-1326
TP63, a member of the TP53 gene family, is a nuclear marker of myoepithelial cells. Antibody against p63 is frequently used to aid in the diagnosis of prostate carcinoma, as well as in the identification of myoepithelial cells in other tissues includ
Autor:
Kellie R. Brown, Christopher P. Johnson, Charles E. Edmiston, Brian D. Lewis, Candace J. Krepel, Jonathan B. Towne, Gary R. Seabrook, Michael P. Goheen
Publikováno v:
Journal of the American College of Surgeons. 203:481-489
Surgical site infections are associated with severe morbidity and mortality. The role of surgical sutures in the etiology of surgical site infection has been the objective of discussion for decades. This study used a standardized in vitro microbiolog
Autor:
Kellie R. Brown, Christopher P. Johnson, Jonathan B. Towne, Brian D. Lewis, Charles E. Edmiston, Michael P. Goheen, Gary R. Seabrook
Publikováno v:
The American Journal of Surgery. 192:344-354
Infection of intravascular or implanted biomedical devices often involves biofilm-forming staphylococci that are recalcitrant to antimicrobial therapy. The present study investigated the activity of 6 antimicrobial agents against biofilm-forming and
Publikováno v:
AORN Journal. 69:1169-1183
Intraoperative sampling of airborne particulates is rarely performed in the OR environment because of technical difficulties associated with sampling methodologies and because of the common belief that airborne contamination is infrequently associate
Publikováno v:
Microscopy and Microanalysis. 21:211-212
IgA nephropathy (IgAN) is a common diagnosis in patients undergoing renal biopsy for hematuria and proteinuria, but histopathology may vary widely among affected patients. Worldwide, IgAN is the most common form of primary glomerulonephritis and is a
Autor:
Sean R. Williamson, Michael P. Goheen, Muhammad T. Idrees, David J. Grignon, Liang Cheng, Jennifer B. Kum
Publikováno v:
Human pathology. 45(4)
A component of syncytial-type multinucleated tumor giant cells is uncommon in clear cell renal cell carcinoma, and the histogenesis, incidence, and clinical implications of this finding are not well understood. We retrieved 13 such tumors from our pa
Semisynthetic echinocandins affect cell wall deposition of Pneumocystis carinii in vitro and in vivo
Autor:
Carole J. Boylan, Michael P. Goheen, W. L. Current, James W. Smith, Sherry F. Queener, Margaret M. Shaw, Chao-Hung Lee, Marilyn S. Bartlett
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:1811-1816
Cyclic lipodepsipeptide compounds of the echinocandin class exhibit broad-spectrum antifungal activity and have been shown to be effective in the treatment of Pneumocystis carinii pneumonia in laboratory animal models. Previous studies have led inves
Autor:
Michael P. Goheen, Denise M. Walker, Lori Graham, Geoffrey S. Kansas, Fredrick M. Pavalko, Claire M. Doerschuk
Publikováno v:
The Journal of Cell Biology
The leukocyte adhesion molecule L-selectin mediates binding to lymph node high endothelial venules (HEV) and contributes to leukocyte rolling on endothelium at sites of inflammation. Previously, it was shown that truncation of the L-selectin cytoplas
Publikováno v:
Ultrastructural Pathology. 19:75-81
A superior-anterior mediastinal tumor was excised from a 50-year-old man. The 207-g mass was encapsulated and multilobulated. It contained adipose tissue and abnormal thymic tissue. In some areas the thymic tissue was characterized by cords and nests