Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael P. Cooreman"'
Autor:
Michael P. Cooreman, Javed Butler, Robert P. Giugliano, Faiez Zannad, Lucile Dzen, Philippe Huot-Marchand, Martine Baudin, Daniel R. Beard, Jean-Louis Junien, Pierre Broqua, Manal F. Abdelmalek, Sven M. Francque
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Lanifibranor, a pan-PPAR agonist, improves liver histology in patients with metabolic dysfunction-associated steatohepatitis (MASH), who have poor cardiometabolic health (CMH) and cardiovascular events as major mortality cause. NATIVE trial
Externí odkaz:
https://doaj.org/article/a8349f7dd9df4b16ac7569db5e4e8c59
Autor:
A. James M. Daveson, Hooi C. Ee, Jane M. Andrews, Timothy King, Kaela E. Goldstein, John L. Dzuris, James A. MacDougall, Leslie J. Williams, Anita Treohan, Michael P. Cooreman, Robert P. Anderson
Publikováno v:
EBioMedicine, Vol 26, Iss C, Pp 78-90 (2017)
Background: Nexvax2® is a novel, peptide-based, epitope-specific immunotherapy intended to be administered by regular injections at dose levels that increase the threshold for clinical reactivity to natural exposure to gluten and ultimately restore
Externí odkaz:
https://doaj.org/article/dddffba30bd84072b2c97201e1ba0294
Autor:
MICHAEL P. COOREMAN, SVEN FRANCQUE, LUCILE DZEN, PHILIPPE HUOT-MARCHAND, JEAN L. JUNIEN, PIERRE BROQUA, MANAL F. ABDELMALEK
Publikováno v:
Diabetes. 71
Lanifibranor therapy resulted in both NASH resolution and fibrosis reduction in the phase 2b NATIVE study in patients with non-cirrhotic NASH, compared to placebo. PPAR signaling is involved in common pathways of NASH and type 2 diabetes (T2D) . We e
Autor:
Yum Lina Yip Sonderegger, Vishal Saundankar, Augstina Ogbonnaya, Manfred Bilzer, Michael P. Cooreman
Publikováno v:
Gastroenterology. 158:S-1308
Publikováno v:
Journal of Biomedical Science. 8:237-247
Hepatitis B virus surface antigen (HBsAg) vaccination has been shown to be effective in preventing hepatitis B virus (HBV) infection. The protection is based on the induction of anti-HBs antibodies against a major cluster of antigenic epitopes of HBs
Autor:
Yaacov Baruch, Savino Bruno, Patrick Marcellin, Niloufar Mobashery, John M. Vierling, Bruce R. Bacon, Michael P. Cooreman, Michael N. Robertson, Luzelena Caro, Peter M. Shaw, Christopher L. Gilbert, Peggy Hwang, Oren Shibolet, Janice Wahl, Christine Fandozzi, Michael P. Manns, Jacqueline Gress, Frank J. Dutko, Anita Y. M. Howe
Publikováno v:
Gastroenterology. 147(2)
Background & Aims MK-5172 is an inhibitor of the hepatitis C virus (HCV) nonstructural protein 3/4A protease; MK-5172 is taken once daily and has a higher potency and barrier to resistance than licensed protease inhibitors. We investigated the effica
Autor:
Choi-Lai Tiong-Yip, Kai Lin, Neil S. Ryder, Beat Weidmann, Sue Ma, Michael P. Cooreman, Joanna E. Boerner
Host factors involved in viral replication are potentially attractive antiviral targets that are complementary to specific inhibitors of viral enzymes, since resistant mutations against the latter are likely to emerge during long-term treatment. It h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2f7c5a6a032d16e5b312bc6b9a4574
https://europepmc.org/articles/PMC1563518/
https://europepmc.org/articles/PMC1563518/
Autor:
Scott L. Friedman, Carmen Langa, Francisco Sanz-Rodríguez, Luisa María Botella, Vlad Ratziu, Michael P. Cooreman, Mercedes Guerrero-Esteo, Carmelo Bernabeu, Calvin P.H. Vary, Jose Ramón Ramirez, Soichi Kojima, Jun Shimada, Tilman Sanchez-Elsner
Publikováno v:
Blood. 100(12)
Endoglin is an endothelial membrane glycoprotein involved in cardiovascular morphogenesis and vascular remodeling. It associates with transforming growth factor-beta (TGF-beta) signaling receptors to bind TGF-beta family members, forming a functional
Autor:
Jorge Laborda, Dan Li, Gutham Narla, Steven Yea, Francis J. Eng, Scott L. Friedman, Michael P. Cooreman, Martin J. Walsh
Publikováno v:
Gastroenterology. 124:A69-A70
Autor:
Jan-Albert Hellings, Acad Medical Ctr, Mark H. Van Roosmalen, Rene H. M. te Morsche, C. M. G. Sunnen, Michael P. Cooreman, Geert Leroux-Roels
Publikováno v:
Gastroenterology. 120:A384-A385