Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Michael P. Citron"'
Autor:
Aimin Tang, Zhifeng Chen, Kara S. Cox, Hua-Poo Su, Cheryl Callahan, Arthur Fridman, Lan Zhang, Sangita B. Patel, Pedro J. Cejas, Ryan Swoyer, Sinoeun Touch, Michael P. Citron, Dhanasekaran Govindarajan, Bin Luo, Michael Eddins, John C. Reid, Stephen M. Soisson, Jennifer Galli, Dai Wang, Zhiyun Wen, Gwendolyn J. Heidecker, Danilo R. Casimiro, Daniel J. DiStefano, Kalpit A. Vora
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Respiratory syncytial virus (RSV) is a leading cause of infant hospitalization. Here, the authors isolate a human monoclonal antibody that binds to a highly conserved epitope on the RSV fusion protein, neutralizes RSV A and B subtypes equipotently an
Externí odkaz:
https://doaj.org/article/353ee58e3241465cbd5aae22b7984ad3
Autor:
Michael P. Citron, Jessica McAnulty, Cheryl Callahan, Walter Knapp, Jane Fontenot, Pablo Morales, Jessica A. Flynn, Cameron M. Douglas, Amy S. Espeseth
Publikováno v:
Pathogens, Vol 10, Iss 11, p 1441 (2021)
One approach to protect new-borns against respiratory syncytial virus (RSV) is to vaccinate pregnant women in the last trimester of pregnancy. The boosting of circulating antibodies which can be transferred to the foetus would offer immune protection
Externí odkaz:
https://doaj.org/article/1c8d05755ffa4400bec63cc9820e65cd
Autor:
Jessica A, Flynn, Teresa, Weber, Pedro J, Cejas, Kara S, Cox, Sinoeun, Touch, Lauren A, Austin, Yangsi, Ou, Michael P, Citron, Bin, Luo, Marian E, Gindy, Kapil, Bahl, Giuseppe, Ciaramella, Amy S, Espeseth, Lan, Zhang
Publikováno v:
Vaccine. 40:4412-4423
In response to immune pressure, influenza viruses evolve, producing drifted variants capable of escaping immune recognition. One strategy for inducing a broad-spectrum immune response capable of recognizing multiple antigenically diverse strains is t
Autor:
Xue Liang, Begüm D. Topçuoğlu, Erin Spofford, Julia M. Maritz, Sushma Kommineni, Cory H. White, Olga Danilchanka, Daria J. Hazuda, Geoffrey D. Hannigan, Teresa M. Weber, Michael P. Citron, Jianying Xiao, Christopher H. Woelk, Daniel C. Freed, Erin Bryant-Hall, Keun-Joong Lee, Jane Fontenot, Gokul Swaminathan, Gino Salituro, Dario A. Gutierrez, Mahika Kadam, James E. Norton, Abigail L. Reens
Publikováno v:
Vaccines
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1340, p 1340 (2021)
Volume 9
Issue 11
Vaccines, Vol 9, Iss 1340, p 1340 (2021)
Emerging evidence demonstrates a connection between microbiome composition and suboptimal response to vaccines (vaccine hyporesponse). Harnessing the interaction between microbes and the immune system could provide novel therapeutic strategies for im
Autor:
Pablo Morales, Cheryl Callahan, Jessica McAnulty, Jessica A. Flynn, Michael P. Citron, Jane Fontenot, Amy S. Espeseth, Walter Knapp, Cameron M. Douglas
Publikováno v:
Pathogens
Pathogens, Vol 10, Iss 1441, p 1441 (2021)
Volume 10
Issue 11
Pathogens, Vol 10, Iss 1441, p 1441 (2021)
Volume 10
Issue 11
One approach to protect new-borns against respiratory syncytial virus (RSV) is to vaccinate pregnant women in the last trimester of pregnancy. The boosting of circulating antibodies which can be transferred to the foetus would offer immune protection
Autor:
Michael P. Citron, Zhiyun Wen, Nickita Mehta, Galit Alter, Amy S. Espeseth, Daniel J. DiStefano, Jishnu Das, Sinoeun Touch, Cheryl Callahan, Jeffrey R. Sachs, Tomer Zohar, Paloma Cejas, Andrew J. Bett, Anush Devadhasan, Douglas A. Lauffenburger, Wiktor Karpinski
Publikováno v:
SSRN Electronic Journal.
Respiratory syncytial virus (RSV) infection is a major cause of severe respiratory illness in both young infants and the elderly. While antibodies represent key correlates of protection, the antibody mechanisms remain poorly understood. Emerging data
Autor:
Andrew J. Bett, Dai Wang, Zhiyun Wen, Andrew H. Latham, Lan Zhang, Kalpit A. Vora, Michael P. Citron, Jeffrey S. Smith, Marian E. Gindy, Christine A. Shaw, Joseph M. Antonello, Jessica A. Flynn, Ryan Swoyer, Cheryl Callahan, Giuseppe Ciaramella, Paloma Cejas, Daniel J. DiStefano, Kapil Bahl, Daniel C. Freed, Kara S. Cox, Gregory O’ Donnell, Amy S. Espeseth, Sinoeun Touch, Jennifer D. Galli, Daria J. Hazuda
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 5, Iss 1, Pp 1-14 (2020)
npj Vaccines, Vol 5, Iss 1, Pp 1-14 (2020)
The RSV Fusion (F) protein is a target for neutralizing antibody responses and is a focus for vaccine discovery; however, the process of RSV entry requires F to adopt a metastable prefusion form and transition to a more stable postfusion form, which
Autor:
Tomer Zohar, Jeff C. Hsiao, Nickita Mehta, Jishnu Das, Anush Devadhasan, Wiktor Karpinski, Cheryl Callahan, Michael P. Citron, Daniel J. DiStefano, Sinoeun Touch, Zhiyun Wen, Jeffrey R. Sachs, Pedro J. Cejas, Amy S. Espeseth, Douglas A. Lauffenburger, Andrew J. Bett, Galit Alter
Publikováno v:
Cell Host & Microbe. 30:41-52.e5
Respiratory syncytial virus (RSV) infection is a major cause of respiratory illness in infants and the elderly. Although several vaccines have been developed, none have succeeded in part due to our incomplete understanding of the correlates of immune
Autor:
Elizabeth Thoryk, David S. Thiriot, Sayda Elbashir, Jeffrey G. Smith, Nicole L Sullivan, Christine A. Shaw, Morgan A. Monslow, Kalpit A. Vora, Nithya Thambi, Daria J. Hazuda, Cook James C, Patrick L. Ahl, Elise Miller, Michael P. Citron, Scott Cosmi
Publikováno v:
Vaccine. 38(36)
Shingles is a painful, blistering rash caused by reactivation of latent varicella-zoster virus (VZV) and most frequently occurs in elderly and immunocompromised individuals. Currently, two approved vaccines for the prevention of shingles are on the m
Autor:
Sinoeun Touch, Chinedu G. Orekie, Cameron M. Douglas, Walter Knapp, Jane Fontenot, Amy S. Espeseth, Zhiyun Wen, Michael P. Citron, Ioan Petrescu, Mona Purcell, Cheryl Callahan, Xiaoping Liang, Sai Prasanth Chamarthy, Manishkumar Patel, Paul McQuade, Daniel Rubins, Shu-An Lin, Alexa Gleason, Matthew Pine
Publikováno v:
Vaccine. 36:2876-2885
Respiratory syncytial virus (RSV) is the most common viral cause of bronchiolitis and pneumonia in children twelve months of age or younger and a significant cause of lower respiratory disease in older adults. As various clinical and preclinical cand