Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Michael P. Carty"'
Publikováno v:
Molecules, Vol 28, Iss 13, p 5202 (2023)
This review uses the National Cancer Institute (NCI) COMPARE program to establish an extensive list of heterocyclic iminoquinones and quinones with similarities in differential growth inhibition patterns across the 60-cell line panel of the NCI Devel
Externí odkaz:
https://doaj.org/article/507f72912ede480fbfb15fe28603829d
Autor:
Ashlynn Ai Li Ler, Michael P. Carty
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
DNA lesions arising from both exogenous and endogenous sources occur frequently in DNA. During DNA replication, the presence of unrepaired DNA damage in the template can arrest replication fork progression, leading to fork collapse, double-strand bre
Externí odkaz:
https://doaj.org/article/e90a697ba2ad4e8696d8e0f5a28174c7
Autor:
Lee-Ann J. Keane, Styliana I. Mirallai, Martin Sweeney, Michael P. Carty, Georgia A. Zissimou, Andrey A. Berezin, Panayiotis A. Koutentis, Fawaz Aldabbagh
Publikováno v:
Molecules, Vol 23, Iss 3, p 574 (2018)
Cell viability studies for benzo[1,2,4]triazin-7-ones and 1,2,4-benzotriazinyl (Blatter-type) radical precursors are described with comparisons made with 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO). All of the stable free radicals were several order
Externí odkaz:
https://doaj.org/article/36f4cdc6199b44dcbc1b0fac81132821
Autor:
Constantina Papatriantafyllopoulou, Patrick McArdle, Constantinos G. Efthymiou, Michael P. Carty, Liam Morrison, George E. Froudakis, Wassillios Papawassiliou, Júlia Mayans, José P. Carvalho, Andrew J. Pell, Albert Escuer, Emmanuel Tylianakis, Meghan Winterlich
Publikováno v:
Materials Advances. 1:2248-2260
Metal organic frameworks (MOFs) have received significant attention in recent years in the areas of biomedical and environmental applications. Among them, mixed metal MOFs, although promising, are relatively few in number in comparison with their hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb15bf3fbdd44371ac47f6f51db9fae9
https://doi.org/10.1039/d0ma00450b
https://doi.org/10.1039/d0ma00450b
Autor:
Dennis A. Smith, Michael Kennedy, Michael P. Carty, Fawaz Aldabbagh, Patrick McArdle, Patrick Kielty, Peter Cannon, Richard J. Singer
Isosorbide was functionalized with furoxan for the first time to give adducts that release nitric oxide up to 7.5 times faster than the commercial vasodilator, isosorbide-5-mononitrate (Is5N). The synthesis was facilitated by MeMgCl-mediated selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc3d7c00551ce072865428162e55fa8
https://eprints.kingston.ac.uk/id/eprint/41155/3/Singer-R-41155-AAM.pdf
https://eprints.kingston.ac.uk/id/eprint/41155/3/Singer-R-41155-AAM.pdf
Publikováno v:
Molecular and cellular biochemistry. 427(1-2)
We have previously demonstrated that the E3 ligase Human Constitutive Photomorphogenic Protein (huCOP1) is expressed in human keratinocytes and negatively regulates p53. The MutS homolog 2 (MSH2) protein plays a central role in DNA MMR mechanism and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2f64abb00da6db1f3c5011e9405a5c
https://pubmed.ncbi.nlm.nih.gov/27995412
https://pubmed.ncbi.nlm.nih.gov/27995412
Publikováno v:
International Journal of Hematology. 96:649-656
Anthracyclines, including doxorubicin, are widely used in the treatment of leukemia. While the effects of doxorubicin on hematopoietic cells have been characterized, less is known about the response of human mesenchymal stem cells (hMSCs) in the bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57106c41ff66283c11646105f1e7eb26
https://doi.org/10.1007/s12185-012-1196-5
https://doi.org/10.1007/s12185-012-1196-5
Publikováno v:
European Journal of Organic Chemistry. 2012:1967-1975
A new synthetic route to ring-fused imidazo[5,4-f]benzimidazoles is reported that can be used to access symmetrical and unsymmetrical quinone anticancer agents. Oxone in formic acid allows cyclisation of o-tert-aminoacetanilides to give ring-fused be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75db1877edf8c6a981202abb452cbdad
https://doi.org/10.1002/ejoc.201101687
https://doi.org/10.1002/ejoc.201101687
Publikováno v:
Cell Cycle. 10:3768-3777
DNA damaging agents are widely used in treatment of hematogical malignancies and solid tumors. While effects on hematopoietic stem cells have been characterized, less is known about the DNA damage response in human mesenchymal stem cells (hMSCs) in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a1bfa27093171194469564d3de73f5
https://doi.org/10.4161/cc.10.21.17972
https://doi.org/10.4161/cc.10.21.17972
Autor:
Beata Kościołek, Michael P. Carty, Renata Grzywa, Józef Oleksyszyn, Marcin Sieńczyk, Anna M. Sokol, Magdalena Radziszewicz
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:2930-2936
A series of new aromatic monoesters of alpha-aminoaralkylphosphonic acids were synthesized by selective hydrolysis of corresponding aromatic diesters of alpha-aminoaralkylphosphonic acids. New potential inhibitors of aminopeptidase N/CD13, an enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf8d0b220332b76343f70de0a77d009
https://doi.org/10.1016/j.bmc.2010.02.056
https://doi.org/10.1016/j.bmc.2010.02.056