Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Michael P. Cahill"'
Autor:
Mary C. Moran, Michael P. Cahill, Matthew G. Brewer, Takeshi Yoshida, Sara Knowlden, Nelissa Perez-Nazario, Patrick M. Schlievert, Lisa A. Beck
Publikováno v:
mSphere, Vol 4, Iss 6 (2019)
ABSTRACT Staphylococcus aureus is the leading cause of skin and soft tissue infections, bacteremia, infective endocarditis, osteoarticular, pleuropulmonary, and device-related infections. Virulence factors secreted by S. aureus, including superantige
Externí odkaz:
https://doaj.org/article/926d2a27531c49c49fb534421f094da9
Autor:
Patrick M. Schlievert, Michael P. Cahill, Bruce S. Hostager, Amanda J. Brosnahan, Aloysius J. Klingelhutz, Francoise A. Gourronc, Gail A. Bishop, Donald Y. M. Leung
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Mucosal and skin tissues form barriers to infection by most bacterial pathogens. Staphylococcus aureus causes diseases across these barriers in part dependent on the proinflammatory properties of superantigens. We showed, through use of a CR
Externí odkaz:
https://doaj.org/article/49782844522c4c8c856aa6a48efa7298
Autor:
Joseph A. Merriman, Elizabeth A. Mueller, Michael P. Cahill, Lisa A. Beck, Amy S. Paller, Jon M. Hanifin, Peck Y. Ong, Lynda Schneider, Denise C. Babineau, Gloria David, Alexandre Lockhart, Keli Artis, Donald Y. M. Leung, Patrick M. Schlievert
Publikováno v:
mSphere, Vol 1, Iss 6 (2016)
ABSTRACT Atopic dermatitis (AD) is an inflammatory skin condition strongly associated with Staphylococcus aureus colonization and infection. S. aureus strains shift in populations in ~10-year intervals depending on virulence factors. Shifts in S. aur
Externí odkaz:
https://doaj.org/article/ddbc7e8f76974b67a73cc7df517e4788
Autor:
Christopher E. Pelt, MD, Salika Shakir, PhD, D(ABMM), Michael J. Cahill, MSc, Jakrapun Pupaibool, MD, Barbara C. Cahill, MD
Publikováno v:
Arthroplasty Today, Vol 27, Iss , Pp 101350- (2024)
Periprosthetic joint infection (PJI) can present challenges in diagnosis and treatment, particularly in the setting of atypical causative organisms such as fungi and mycobacteria. Herein, we present a case and provide a review of the diagnosis and tr
Externí odkaz:
https://doaj.org/article/499d352c0e6c4a868fe05254ecc5c22b
Autor:
Kathryn J. Bjornson, Michael E. Cahill
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102829- (2024)
Summary: Dendritic spines are protrusions on dendrites forming the postsynaptic aspect of excitatory connections within the brain. Spine morphology is associated with synaptic functional strength and the spatial regulation of protein nanodomains with
Externí odkaz:
https://doaj.org/article/0e0b2d3a7f50429fac88a684b47b372f
Autor:
Kathryn J. Bjornson, Amanda M. Vanderplow, Yezi Yang, Danielle R. Anderson, Bailey A. Kermath, Michael E. Cahill
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107566- (2023)
Summary: The effects of repeated stress on cognitive impairment are thought to be mediated, at least in part, by reductions in the stability of dendritic spines in brain regions critical for proper learning and memory, including the hippocampus. Smal
Externí odkaz:
https://doaj.org/article/73280224e82645998199eac1d6281f3e
Autor:
Louise N. Cooney, Kevin D. O’Shea, Hannah J. Winfield, Michael M. Cahill, Larry T. Pierce, Florence O. McCarthy
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1191 (2023)
The evolution of bisindolyl maleimides and indolyl maleimide derivatives and their unique biological activities have stimulated great interest in medicinal chemistry programs. Bisindolylmaleimide (BIM)-type compounds arise from natural sources such a
Externí odkaz:
https://doaj.org/article/0598606e4a584275865e2453fc532b12
Autor:
Bashar M. Thejer, Partho P. Adhikary, Amandeep Kaur, Sarah L. Teakel, Ashleigh Van Oosterum, Ishith Seth, Marina Pajic, Katherine M. Hannan, Megan Pavy, Perlita Poh, Jalal A. Jazayeri, Thiri Zaw, Dana Pascovici, Marina Ludescher, Michael Pawlak, Juan C. Cassano, Lynne Turnbull, Mitra Jazayeri, Alexander C. James, Craig P. Coorey, Tara L. Roberts, Simon J. Kinder, Ross D. Hannan, Ellis Patrick, Mark P. Molloy, Elizabeth J. New, Tanja N. Fehm, Hans Neubauer, Ewa M. Goldys, Leslie A. Weston, Michael A. Cahill
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-24 (2020)
Abstract Background Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. It contains phosphorylated tyrosines which evolutionarily preceded deuterostome gastr
Externí odkaz:
https://doaj.org/article/2bd658d87bfa450aac0f899967a1efce
Autor:
Bashar M. Thejer, Partho P. Adhikary, Sarah L. Teakel, Johnny Fang, Paul A. Weston, Saliya Gurusinghe, Ayad G. Anwer, Martin Gosnell, Jalal A. Jazayeri, Marina Ludescher, Lesley-Ann Gray, Michael Pawlak, Robyn H. Wallace, Sameer D. Pant, Marie Wong, Tamas Fischer, Elizabeth J. New, Tanja N. Fehm, Hans Neubauer, Ewa M. Goldys, Jane C. Quinn, Leslie A. Weston, Michael A. Cahill
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-19 (2020)
Abstract Background Progesterone receptor membrane component 1 (PGRMC1) is often elevated in cancers, and exists in alternative states of phosphorylation. A motif centered on PGRMC1 Y180 was evolutionarily acquired concurrently with the embryological
Externí odkaz:
https://doaj.org/article/d57b2568cb0049e990fdf5278618e4ac
Autor:
Elizabeth A. Kiernan, Tao Wang, Amanda M. Vanderplow, Sneha Cherukuri, Michael E. Cahill, Jyoti J. Watters
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Sleep disordered breathing (SDB) affects 3–5% of the pediatric population, including neonates who are highly susceptible due to an underdeveloped ventilatory control system, and REM-dominated sleep. Although pediatric SDB is associated with poor co
Externí odkaz:
https://doaj.org/article/639224b42e7242f18014a1fb178a86a8