Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Michael P. Vitek"'
Autor:
Katherine I. Swenson-Fields, Christopher J. Ward, Micaila E. Lopez, Shaneann Fross, Anna L. Heimes Dillon, James D. Meisenheimer, Adib J. Rabbani, Emily Wedlock, Malay K. Basu, Kyle P. Jansson, Peter S. Rowe, Jason R. Stubbs, Darren P. Wallace, Michael P. Vitek, Timothy A. Fields
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
We and others have previously shown that the presence of renal innate immune cells can promote polycystic kidney disease (PKD) progression. In this study, we examined the influence of the inflammasome, a key part of the innate immune system, on PKD.
Externí odkaz:
https://doaj.org/article/9c08d54c8b8b492abf160be7de40df31
Autor:
Bo Wang, Feng-Wan Zhang, Wei-Xiao Wang, Yan-Yan Zhao, Su-Yue Sun, Jin-Hong Yu, Michael P. Vitek, George F. Li, Rui Ma, Shiwei Wang, Zhiliang Hu, Wei Chen
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The emergence of pandrug-resistant bacteria breaks through the last line of defense and raises fear among people of incurable infections. In the post-antibiotic era, the pharmaceutical field turns to seek non-conventional anti-infective agents. Antim
Externí odkaz:
https://doaj.org/article/54d1407efd0247b6b27e18b2d1ea2399
Autor:
Celimene Galiger, Meike Dahlhaus, Michael Peter Vitek, Klaus-Michael Debatin, Christian Beltinger
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Neuroblastoma (NB) is the most common extracranial solid tumor in childhood and has a poor prognosis in high-risk cases, requiring novel therapies. Pathways that depend on phospho-signaling maintain the aggressiveness of NB. Protein phosphatase 2 (PP
Externí odkaz:
https://doaj.org/article/33792a088fca4dea8283062f59d25b98
Autor:
Reinaldo B. Oriá, Raul S. Freitas, Cássia R. Roque, José Carlos R. Nascimento, Ana Paula Silva, João O. Malva, Richard L. Guerrant, Michael P. Vitek
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1086 (2023)
Apolipoprotein E (apoE) mimetic peptides are engineered fragments of the native apoE protein’s LDL-receptor binding site that improve the outcomes following a brain injury and intestinal inflammation in a variety of models. The vicious cycle of ent
Externí odkaz:
https://doaj.org/article/27e4080c75d24c9d91fc6f8a9bacae1e
Publikováno v:
ASN Neuro, Vol 13 (2021)
Metabolic adaptations in the brain are critical to the establishment and maintenance of normal cellular functions and to the pathological responses to disease processes. Here, we have focused on specific metabolic pathways that are involved in immune
Externí odkaz:
https://doaj.org/article/28b6f04885ce4b78a02b9fd83096d6c7
Autor:
Michael P. Vitek, Joseph A. Araujo, Michael Fossel, Barry D. Greenberg, Gareth R. Howell, Stacey J. Sukoff Rizzo, Nicholas T. Seyfried, Andrea J. Tenner, Paul R. Territo, Manfred Windisch, Lisa J. Bain, April Ross, Maria C. Carrillo, Bruce T. Lamb, Rebecca M. Edelmayer
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Over 5 million Americans and 50 million individuals worldwide are living with Alzheimer's disease (AD). The progressive dementia associated with AD currently has no cure. Although clinical trials in patients are ultimately required to find s
Externí odkaz:
https://doaj.org/article/0eb0a3dc83454bcf9a7b7193168aa3c0
Autor:
Koichi Sato, Takashi Ohama, Tatsuya Usui, Yoshitaka Hippo, Tetsuya Matsuura, Michael P. Vitek, Masanobu Oshima, Hiroko Oshima, Hiroaki Nagano, Shoichi Hazama, Shigefumi Yoshino, Hiroko Takenouchi, Yusuke Sakai, Masashi Sakurai, Hideyoshi Kawasaki, Kazuhiro Yoshimura, Shunya Tsuji, Ryotaro Yabe, Shuhei Enjoji
Gastric cancer is the fifth most common malignancy and the third leading cause of cancer-related deaths worldwide. Chemotherapies against gastric cancer often fail, with cancer recurrence due potentially to the persistence of cancer stem cells. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a864b489e0b4324020de729a78cd2f2
https://doi.org/10.1158/1541-7786.c.6540399.v1
https://doi.org/10.1158/1541-7786.c.6540399.v1
Autor:
Koichi Sato, Takashi Ohama, Tatsuya Usui, Yoshitaka Hippo, Tetsuya Matsuura, Michael P. Vitek, Masanobu Oshima, Hiroko Oshima, Hiroaki Nagano, Shoichi Hazama, Shigefumi Yoshino, Hiroko Takenouchi, Yusuke Sakai, Masashi Sakurai, Hideyoshi Kawasaki, Kazuhiro Yoshimura, Shunya Tsuji, Ryotaro Yabe, Shuhei Enjoji
This file contains detailed material and methods, and supplemental data related with Fig. 1g, Fig. 2a, b, Fig. 3c, d, Fig. 4a, b, c, Fig. 5c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7502b222c7bf4262af1a17c9faaee87c
https://doi.org/10.1158/1541-7786.22512972
https://doi.org/10.1158/1541-7786.22512972
Autor:
Brian J. Druker, Dale J. Christensen, María D. Odero, Michael P. Vitek, Rosalie Sears, Jeffrey W. Tyner, Jessica Oddo, Christopher A. Eide, Raffaella Pippa, Ryan J. MacKenzie, Anupriya Agarwal
PDF file - 73KB, CML (Table 1) and AML (Table 2) Patient sample information.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0377ba428f825d16101282d07fc3f0
https://doi.org/10.1158/1078-0432.22449378
https://doi.org/10.1158/1078-0432.22449378
Autor:
Brian J. Druker, Dale J. Christensen, María D. Odero, Michael P. Vitek, Rosalie Sears, Jeffrey W. Tyner, Jessica Oddo, Christopher A. Eide, Raffaella Pippa, Ryan J. MacKenzie, Anupriya Agarwal
PDF file - 58KB, Combination index (CI) values.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185b438edbe87c73cbe82aed37ba8bb1
https://doi.org/10.1158/1078-0432.22449381
https://doi.org/10.1158/1078-0432.22449381