Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Michael P. McConnell"'
Autor:
Morteza Naghavi, Anthony P. Reeves, Kyle Atlas, Chenyu Zhang, Thomas Atlas, Claudia I. Henschke, David F. Yankelevitz, Matthew J. Budoff, Dong Li, Sion K. Roy, Khurram Nasir, Sabee Molloi, Zahi Fayad, Michael V. McConnell, Ioannis Kakadiaris, David J. Maron, Jagat Narula, Kim Williams, Prediman K. Shah, Daniel Levy, Nathan D. Wong
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Coronary artery calcium (CAC) scans contain valuable information beyond the Agatston Score which is currently reported for predicting coronary heart disease (CHD) only. We examined whether new artificial intelligence (AI) applied to CAC scan
Externí odkaz:
https://doaj.org/article/5dcdbca0040f43b1b76088122904b1dd
Autor:
David M. Squirrell, BMedSci (Hons), MBChB (Hons), Song Yang, PhD, Li Xie, PhD, Songyang Ang, BEng, Mohammadi Moghadam, PhD, Ehsan Vaghefi, PhD, Michael V. McConnell, MD MSEE
Publikováno v:
JACC: Advances, Vol 3, Iss 12, Pp 101410- (2024)
Background: High systolic blood pressure (SBP) is one of the leading modifiable risk factors for premature cardiovascular death. The retinal vasculature exhibits well-documented adaptations to high SBP and these vascular changes are known to correlat
Externí odkaz:
https://doaj.org/article/cfe53be54ec644e086e2448dfcfce760
Autor:
Chen Sun, Kunal Kathuria, Sarah B. Emery, ByungJun Kim, Ian E. Burbulis, Joo Heon Shin, Brain Somatic Mosaicism Network, Daniel R. Weinberger, John V. Moran, Jeffrey M. Kidd, Ryan E. Mills, Michael J. McConnell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract When somatic cells acquire complex karyotypes, they often are removed by the immune system. Mutant somatic cells that evade immune surveillance can lead to cancer. Neurons with complex karyotypes arise during neurotypical brain development,
Externí odkaz:
https://doaj.org/article/3c1b3462f5dc401c808fdd785991305a
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/c40866f9013a42d98d358c195d9110ce
Publikováno v:
Vaccines, Vol 12, Iss 1, p 68 (2024)
The emergence and global dissemination of bacterial strains from numerous species with resistance to multiple antibiotic classes has increased in recent years, both in the healthcare and the community setting [...]
Externí odkaz:
https://doaj.org/article/7c110fecf62545a49f453f30cb2b8bd4
Autor:
Nadine Michel, Heather M. Raimer Young, Naomi D. Atkin, Umar Arshad, Reem Al-Humadi, Sandeep Singh, Arkadi Manukyan, Lana Gore, Ian E. Burbulis, Yuh-Hwa Wang, Michael J. McConnell
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Neurons are overproduced during cerebral cortical development. Neural progenitor cells (NPCs) divide rapidly and incur frequent DNA double-strand breaks (DSBs) throughout cortical neurogenesis. Although half of the neurons born during neurod
Externí odkaz:
https://doaj.org/article/afbddd025bee472c8522a305ded18559
Autor:
Mireia López-Siles, Zaira Moure, Aly Salimo Muadica, Sergio Sánchez, Raquel Cruces, Alicia Ávila, Noelia Lara, Pamela Carolina Köster, Alejandro Dashti, Jesús Oteo-Iglesias, David Carmena, Michael J. McConnell
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
BackgroundExtended-spectrum ß-lactamase-producing Enterobacterales (ESBL-E) are a serious threat among emerging antibiotic resistant bacteria. Particularly, the number of cases of ESBL-E infections reported in children has been increasing in recent
Externí odkaz:
https://doaj.org/article/d525c71757884b8185c5e9f196477947
Autor:
Sean Bae, Silviu Borac, Yunus Emre, Jonathan Wang, Jiang Wu, Mehr Kashyap, Si-Hyuck Kang, Liwen Chen, Melissa Moran, Julie Cannon, Eric S. Teasley, Allen Chai, Yun Liu, Neal Wadhwa, Michael Krainin, Michael Rubinstein, Alejandra Maciel, Michael V. McConnell, Shwetak Patel, Greg S. Corrado, James A. Taylor, Jiening Zhan, Ming Jack Po
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-10 (2022)
Bae et al. prospectively evaluated smartphone camera-based techniques for measuring heart rate and respiratory rate. They found measurements were accurate across a range of pre-defined subgroups.
Externí odkaz:
https://doaj.org/article/2ebc5cc2cff14e5ca029e6e31d25fd42
Autor:
María Pérez-Vázquez, Carla López-Causapé, Andrés Corral-Lugo, Michael J. McConnell, Jesús Oteo-Iglesias, Antonio Oliver, Antonio J. Martín-Galiano
Publikováno v:
Microorganisms, Vol 11, Iss 10, p 2486 (2023)
Mutations leading to upregulation of efflux pumps can produce multiple drug resistance in the pathogen Pseudomonas aeruginosa. Changes in their DNA binding regions, i.e., palindromic operators, can compromise pump depression and subsequently enhance
Externí odkaz:
https://doaj.org/article/f8211252f8564f5b8d3b80c57eeafdc5
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2023)
Acinetobacter baumannii is an important causative agent of hospital acquired infections. In addition to acquired resistance to many currently-available antibiotics, it is intrinsically resistant to fosfomycin. It has previously been shown that AmpD a
Externí odkaz:
https://doaj.org/article/c20a091c32684238bb7e9d3602e91cb3