Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Michael P W Grocott"'
Autor:
Ahilanandan Dushianthan, Paul Mouncey, Daniel Martin, Lamprini Lampro, Tasnin Shahid, Victoria Goss, Amelia Francis Johnson, William Herbert, Angelica Cazley, Mark Lamond, William Jones, Karen Salmon, Florence Neyroud, Magdalena Minnion, Julian Lentaigne, Grielof Koster, Madhuri Panchal, Anthony D Postle, Helen Moyses, Michael P W Grocott, Martin Feelisch
Publikováno v:
NIHR Open Research, Vol 4 (2024)
Background MecROX is a mechanistic sub-study of the UK-ROX trial which was designed to evaluate the clinical and cost-effectiveness of a conservative approach to oxygen therapy for invasively ventilated adults in intensive care. This is based on the
Externí odkaz:
https://doaj.org/article/2d78ef0bea914040a6d45e0af39db2f2
Autor:
Stephanie O. Ibekwe, Jean Deschamps, Michael P W Grocott, Yafen Liang, Andrew Shaw, Tjorvi E. Perry, POQI IX Collaborators
Publikováno v:
Perioperative Medicine, Vol 12, Iss 1, Pp 1-12 (2023)
Abstract Background The right ventricle (RV) plays a central role in the maintenance of effective cardiac pump function. Despite overwhelming evidence that perioperative RV dysfunction (RVD) and failure (RVF) are associated with poor clinical outcome
Externí odkaz:
https://doaj.org/article/d5bb09bec23d44a4ac2e8a248c61ea2e
Autor:
David Baldwin, Michael P W Grocott, Andrew Bates, Natalie Pattison, Rebecca Cusack, Julie Highfield, Hannah Golding, Sophie Rushbrook
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Introduction Post-traumatic symptoms are common among patients discharged from intensive care units (ICUs), adversely affecting well-being, increasing healthcare utilisation and delaying return to work. Non-pharmacological approaches (eg, music, ther
Externí odkaz:
https://doaj.org/article/a3c0a22fc481472c82861984da796407
Autor:
Michael P W Grocott, Helen Roberts, Andrew Bates, Jane Murphy, Sandy Jack, Judit Varkonyi-Sepp, Stephen Eu Ruen Lim, Samantha Jane Meredith
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction Physical activity (PA) and replete nutritional status are key to maintaining independence and improving frailty status among frail older adults. In response to the COVID-19 pandemic, healthcare has increasingly turned to virtual modes of
Externí odkaz:
https://doaj.org/article/3af05e6c555b40739fa37c9a57e313f5
Autor:
Luke Bracegirdle, Matthew Stubbs, Rezaur Rahman, Alexander I R Jackson, Helmi C Burton-Papp, Robert Chambers, Sanjay Gupta, Michael P W Grocott, Ahilanandan Dushianthan
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0296379 (2023)
BackgroundCOVID-19 placed immense strain on healthcare systems, necessitating innovative responses to the surge of critically ill patients, particularly those requiring mechanical ventilation. In this report, we detail the establishment of a dedicate
Externí odkaz:
https://doaj.org/article/d5240a7f310b4d9088bc99257cefe132
Autor:
Luke Bracegirdle, Alexander Jackson, Ryan Beecham, Maria Burova, Elsie Hunter, Laura G Hamilton, Darshni Pandya, Clare Morden, Michael P W Grocott, Andrew Cumpstey, Ahilanandan Dushianthan, REACT COVID-19 Investigators
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0269471 (2022)
BackgroundAcute hypoxic respiratory failure (AHRF) is a hallmark of severe COVID-19 pneumonia and often requires supplementary oxygen therapy. Critically ill COVID-19 patients may require invasive mechanical ventilation, which carries significant mor
Externí odkaz:
https://doaj.org/article/ad01b35dad54432f96c15fc8c3e7674f
Autor:
Michael P W Grocott, Andrew Bates, June Davis, Clare Shaw, Andrew Scott, Chloe Grimmett, Malcolm West, Sandy Jack, Stephen Wootton, Anna Campbell, Samantha Leggett, Judit Varkonyi-Sepp, Rachael Barlow, Joanna Ashcroft, Helen Moyes, Lesley Hawkins, Denny Z H Levett, Fran Williams
Publikováno v:
BMJ Open, Vol 11, Iss 8 (2021)
Externí odkaz:
https://doaj.org/article/22148c1c8844411f8e16080e4f1a60ee
Autor:
Ahilanandan Dushianthan, Rebecca Cusack, Grielof Koster, Michael P W Grocott, Anthony D Postle
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221595 (2019)
Although the distribution of cellular membrane phospholipid composition is well characterised in human erythrocytes, in-vivo turnover and dynamic flux of phospholipids between plasma and erythrocytes in physiological and in particular during disease
Externí odkaz:
https://doaj.org/article/3deef218d1ef47538a2b4c56c98660f2
Autor:
Malcolm A West, Lisa Loughney, Daniel Lythgoe, Christopher P Barben, Valerie L Adams, William E Bimson, Michael P W Grocott, Sandy Jack, Graham J Kemp
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e111526 (2014)
BackgroundIn the United Kingdom, patients with locally advanced rectal cancer routinely receive neoadjuvant chemoradiotherapy. However, the effects of this on physical fitness are unclear. This pilot study is aimed to investigate the effect of neoadj
Externí odkaz:
https://doaj.org/article/105201bbcbf64986a28872b082cf8d9f
Autor:
Mario Siervo, Heather L Riley, Bernadette O Fernandez, Carl A Leckstrom, Daniel S Martin, Kay Mitchell, Denny Z H Levett, Hugh E Montgomery, Monty G Mythen, Michael P W Grocott, Martin Feelisch, Caudwell Xtreme Everest Research Group
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94915 (2014)
The mechanisms by which low oxygen availability are associated with the development of insulin resistance remain obscure. We thus investigated the relationship between such gluco-insular derangements in response to sustained (hypobaric) hypoxemia, an
Externí odkaz:
https://doaj.org/article/edf230d14fea46c18f716739ea9c1474