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pro vyhledávání: '"Michael P Nicoll"'
Autor:
Michael P Nicoll, William Hann, Maitreyi Shivkumar, Laura E R Harman, Viv Connor, Heather M Coleman, João T Proença, Stacey Efstathiou
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005539 (2016)
Herpes simplex virus 1 (HSV-1) establishes life-long latent infection within sensory neurons, during which viral lytic gene expression is silenced. The only highly expressed viral gene product during latent infection is the latency-associated transcr
Externí odkaz:
https://doaj.org/article/f4caff8f8fb647f38af1659e1e2223c7
Publikováno v:
Journal of General Virology. 97:767-777
Herpes simplex virus type 1 (HSV-1) establishes a latent infection in sensory neurons from which the virus can periodically reactivate. Whilst latency establishment is thought to result from a failure to express immediate-early genes, we have previou
Autor:
Janet S. May, Philip G. Stevenson, Ricardo Milho, Stacey Efstathiou, Michael P. Nicoll, Maitreyi Shivkumar
Publikováno v:
Journal of Virology
Herpes simplex virus 1 (HSV-1) is a ubiquitous and important human pathogen. It is known to persist in trigeminal ganglia (TG), but how it reaches this site has been difficult to determine, as viral transmission is sporadic, pathogenesis is complicat
Autor:
Viv Connor, Stacey Efstathiou, João T. Proença, Maitreyi Shivkumar, William Hann, Heather M. Coleman, Michael P. Nicoll, Laura E. R. Harman
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005539 (2016)
PLoS Pathogens
PLoS Pathogens
Herpes simplex virus 1 (HSV-1) establishes life-long latent infection within sensory neurons, during which viral lytic gene expression is silenced. The only highly expressed viral gene product during latent infection is the latency-associated transcr
Publikováno v:
Journal of Virology. 86:8848-8858
Herpes simplex virus 1 (HSV-1) can establish life-long latent infection in sensory neurons, from which periodic reactivation can occur. During latency, viral gene expression is largely restricted to the latency-associated transcripts (LATs). While no
Autor:
Chris M. Preston, João T. Proença, Michael P. Nicoll, Stacey Efstathiou, Heather M. Coleman, Jane Arthur, Viv Connor
Publikováno v:
The Journal of General Virology
Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Cre reporter mouse syste
Publikováno v:
Fems Microbiology Reviews
Herpes simplex virus type 1 is a neurotropic herpesvirus that establishes latency within sensory neurones. Following primary infection, the virus replicates productively within mucosal epithelial cells and enters sensory neurones via nerve termini. T