Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Michael P Hagan"'
Publikováno v:
Viruses, Vol 16, Iss 6, p 895 (2024)
This review accompanies the Special Issue on the subject of physical virology, which features work presented at the recent Gordon Research Conference (GRC) on this topic [...]
Externí odkaz:
https://doaj.org/article/7b35ba3d5e1746ae8b98080aa689c0ac
Autor:
Michael F Hagan, Farzaneh Mohajerani
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 5, p e1010652 (2023)
Liquid condensate droplets with distinct compositions of proteins and nucleic acids are widespread in biological cells. While it is known that such droplets, or compartments, can regulate irreversible protein aggregation, their effect on reversible s
Externí odkaz:
https://doaj.org/article/cc7ca46a37b845cd8a48273482ceb8d3
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Systems of confined active filaments within a deformable vesicle are of relevance for development of active materials constructed from anisotropic particles. The authors propose a framework to control the transformations of the vesicle shape and fila
Externí odkaz:
https://doaj.org/article/95941c63ed69400f874eaa35b518bb5d
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 16, Iss , Pp 85-88 (2020)
This study aimed to establish an efficient planning technique for low dose whole lung treatment that can be implemented rapidly and safely. The treatment technique developed here relied only on chest radiograph and a simple empirical monitor unit cal
Externí odkaz:
https://doaj.org/article/6c3b8c657f4e4505aa4635deecf5ad61
Autor:
Sanjay Dharmavaram, Selene Baochen She, Guillermo Lázaro, Michael Francis Hagan, Robijn Bruinsma
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 8, p e1006602 (2019)
The formation of a membrane-enveloped virus starts with the assembly of a curved layer of capsid proteins lining the interior of the plasma membrane (PM) of the host cell. This layer develops into a spherical shell (capsid) enveloped by a lipid-rich
Externí odkaz:
https://doaj.org/article/64d9dac45c8c4d028ad54c6076e1b948
Autor:
Paul Dent, Steven Grant, Paul B. Fisher, David T. Curiel, Adly Yacoub, Michael P. Hagan, Hossein Hamed, Mohamed Rahmani, Clint Mitchell, Guo Zhang, Margaret A. Park
Supplementary Material from Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341421c16c147e6328121a88b3ad3b96
https://doi.org/10.1158/1535-7163.22484975.v1
https://doi.org/10.1158/1535-7163.22484975.v1
Autor:
Paul Dent, Steven Grant, Paul B. Fisher, David T. Curiel, Adly Yacoub, Michael P. Hagan, Hossein Hamed, Mohamed Rahmani, Clint Mitchell, Guo Zhang, Margaret A. Park
Prior studies have noted that inhibitors of mitogen-activated protein kinase (MAPK) kinase 1/2 (MEK1/2) enhanced geldanamycin lethality in malignant hematopoietic cells by promoting mitochondrial dysfunction. The present studies focused on defining t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de42d1df34864f0761a6e2471285f1d5
https://doi.org/10.1158/1535-7163.c.6531689.v1
https://doi.org/10.1158/1535-7163.c.6531689.v1
Autor:
Charlotte F. Kelley, Emily M. Messelaar, Tania L. Eskin, Shiyu Wang, Kangkang Song, Kalanit Vishnia, Agata N. Becalska, Oleg Shupliakov, Michael F. Hagan, Dganit Danino, Olga S. Sokolova, Daniela Nicastro, Avital A. Rodal
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2597-2609 (2015)
F-BAR domain proteins regulate and sense membrane curvature by interacting with negatively charged phospholipids and assembling into higher-order scaffolds. However, regulatory mechanisms controlling these interactions are poorly understood. Here, we
Externí odkaz:
https://doaj.org/article/f4e783064bf04fd8931e25a2b98a39f3
Autor:
Ruchika Gutt, Sheetal Malhotra, Katherine Faricy-Anderson, Steve P. Lee, George Dawson, Edwinette Moses, Lori Hoffman-Hogg, Helen Fosmire, Abhishek A Solanki, Michael P Hagan, Maria D. Kelly, Ronald H. Shapiro
Publikováno v:
JCO Oncology Practice. 17:e1913-e1922
PURPOSE: Most Veterans Health Administration hospitals do not have radiation oncology (RO) departments on-site. The purpose of this study is to determine the impact of on-site RO on referral patterns and timeliness of palliative radiation therapy (PR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7718a00b8c4f92d8a68b37490b1e63
https://doi.org/10.1200/op.20.00981
https://doi.org/10.1200/op.20.00981
Autor:
Farzaneh Mohajerani, Michael F Hagan
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 7, p e1006351 (2018)
Bacterial microcompartments are large, roughly icosahedral shells that assemble around enzymes and reactants involved in certain metabolic pathways in bacteria. Motivated by microcompartment assembly, we use coarse-grained computational and theoretic
Externí odkaz:
https://doaj.org/article/a44e07b3b33a4e81b770c6f5493b3b7c